Zu "K06171" wurden 47 Artikel gefunden!
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Anti-NCSTN
Artikelnummer: ATA-HPA051793.100
Rabbit Polyclonal NCSTN Antibody against Human nicastrin. Validated for Western Blot. Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Interspecies information: Highest antigen sequence indentity to the following orthologs: ENSMUSG00000003458: 87%, ENSRNOG00000005355: 88%. Protein...
| Schlagworte: | Anti-NCSTN, Anti-KIAA0253, Anti-Nicastrin |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
Anti-Nicastrin
Artikelnummer: A304-464A
Protein function: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein) (PubMed:10993067, PubMed:12679784, PubMed:25043039, PubMed:26280335). The gamma-...
| Schlagworte: | Anti-NCSTN, Anti-KIAA0253, Anti-Nicastrin |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-Nicastrin
Artikelnummer: 600-401-DB1
Anti-Nicastrin Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Nicastrin from other sources has not been determined. Protein function: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage...
| Schlagworte: | Anti-NCSTN, Anti-KIAA0253, Anti-Nicastrin |
| Anwendung: | ELISA, IHC, IFM, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
848,00 €
Anti-Nicastrin
Artikelnummer: 600-401-DB2
Anti-Nicastrin Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Nicastrin from other sources has not been determined. Protein function: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage...
| Schlagworte: | Anti-NCSTN, Anti-KIAA0253, Anti-Nicastrin |
| Anwendung: | ELISA, IHC, IFM, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
848,00 €
Anti-Nicastrin
Artikelnummer: NSJ-R31374
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Nicastrin, also known as NCSTN, is aproteinthat is a part of the gamma secretase protein complex. It is mapped to 1q23.2. This gene is not catalytically active, but instead promotes the maturation and proper trafficking of the other proteins in the gamma...
| Schlagworte: | Anti-NCSTN, Anti-KIAA0253, Anti-Nicastrin, Nicastrin Antibody |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
790,00 €
Anti-NCSTN
Artikelnummer: E-AB-11441.120
This gene encodes a type I transmembrane glycoprotein that is an integral component of the multimeric gamma-secretase complex. The encoded protein cleaves integral membrane proteins, including Notch receptors and beta-amyloid precursor protein, and may be a stabilizing cofactor required for gamma-secretase complex...
| Schlagworte: | Anti-NCSTN, Anti-KIAA0253, Anti-Nicastrin, NCSTN Polyclonal Antibody |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
Anti-NCSTN
Artikelnummer: E-AB-15254.120
This gene encodes a type I transmembrane glycoprotein that is an integral component of the multimeric gamma-secretase complex. The encoded protein cleaves integral membrane proteins, including Notch receptors and beta-amyloid precursor protein, and may be a stabilizing cofactor required for gamma-secretase complex...
| Schlagworte: | Anti-NCSTN, Anti-KIAA0253, Anti-Nicastrin, NCSTN Polyclonal Antibody |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
MK-0752
Artikelnummer: Cay16706-5
gamma-Secretase is a protease complex that cleaves single-pass transmembrane proteins, such as Notch receptors and beta-amyloid precursor protein (APP), within the transmembrane domain. MK-0752 is a potent, reversible inhibitor of gamma-secretase, reducing the cleavage of APP to Abeta40 in human neuroblastoma...
| Schlagworte: | cis-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)-cyclohexanepropanoic acid |
| Anwendung: | gamma-secretase inhibitor |
| CAS | 471905-41-6 |
| MW: | 442.9 D |
ab 102,00 €
LY-450139
Artikelnummer: LKT-L9701.1
GHS-R1a agonist, gamma-secretase inhibitor.
| Schlagworte: | Semagacestat |
| Anwendung: | gamma-secretase inhibitor |
| CAS | 425386-60-3 |
| MW: | 361.44 D |
ab 104,00 €
Anti-NCSTN / Nicastrin
Artikelnummer: ARG40091.100
Protein function: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein) (PubMed:10993067, PubMed:12679784, PubMed:25043039, PubMed:26280335, PubMed:30598546,...
| Schlagworte: | Anti-NCSTN, Anti-KIAA0253, Anti-Nicastrin |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse, rat |
707,00 €
BMS-708163
Artikelnummer: LKT-B5075.1
gamma-Secretase inhibitor.
| Schlagworte: | Avagacestat, BMS708163 |
| Anwendung: | gamma-secretase inhibitor |
| CAS | 1146699-66-2 |
| MW: | 520.88 D |
ab 94,00 €
Anti-NCSTN
Artikelnummer: ATA-HPA054846.100
Protein function: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid- beta precursor protein) (PubMed:10993067, PubMed:12679784, PubMed:25043039, PubMed:26280335, PubMed:30598546,...
| Schlagworte: | Anti-NCSTN, Anti-KIAA0253, Anti-Nicastrin |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €