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Zu "K06128" wurden 24 Artikel gefunden!
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Artikelnummer: Cay17630-1
Lysophospholipase 1 (LYPLA1) is a protein palmitoyl thioesterase responsible for depalmitoylation of the oncogene HRas. Palmitoylation of such oncogenes is thought to be required for trafficking and malignant transformation, making LYPLA1 a target for downregulating oncogenic signaling. ML-211 is a carbamate-based...
Schlagworte: | [4-(1,1-dimethylethyl)-1-piperidinyl][4-(hydroxydiphenylmethyl)-2H-1,2,3-triazol-2-yl]-methanone |
Anwendung: | LYPLA1 / LYPLA2 inhibitor |
CAS | 2205032-89-7 |
MW: | 418.5 D |
ab 50,00 €
Artikelnummer: Cay18523-1
Lysophospholipase 1 (LYPLA1) is a protein palmitoyl thioesterase responsible for depalmitoylation of the oncogene HRas. Palmitoylation of such oncogenes is thought to be required for trafficking and malignant transformation, making LYPLA1 a target for downregulating oncogenic signaling. ML-348 is a reversible LYPLA1...
Schlagworte: | CID 3238952, SID 160654487, N-[2-chloro-5-(trifluoromethyl)phenyl]-4-(2-furanylcarbonyl)-1-piperazineacetamide |
Anwendung: | Reversible LYPLA1 inhibitor |
CAS | 899713-86-1 |
MW: | 415.8 D |
ab 43,00 €
Artikelnummer: G-CAB4419.100
WB 1:500 - 1:2000. Protein function: Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity toward KCNMA1. Has low lysophospholipase activity. [The UniProt Consortium]
Schlagworte: | Anti-APT1, Anti-APT-1, Anti-LPL-I, Anti-hAPT1, Anti-LYPLA1, Anti-LysoPLA I, EC=3.1.2.-, Anti-Lysophospholipase I,... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 352,00 €
Artikelnummer: G-PACO28090.50
Lypla1 Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Mouse and for use in ELISA, IF applications. Lypla1 Antibody is a high quality polyclonal antibody for research use only.. Protein function: Acts as a acyl-protein thioesterase hydrolyzing fatty acids from S-acylated cysteine...
Schlagworte: | Anti-Apt1, Anti-LPL-I, Anti-APT-1, Anti-Lypla1, Anti-LysoPLA I, EC=3.1.2.-, Anti-Lysophospholipase I,... |
Anwendung: | ELISA, IF |
Wirt: | Rabbit |
Spezies-Reaktivität: | mouse |
363,00 €
Artikelnummer: ATA-HPA050941.100
Protein function: Acts as a acyl-protein thioesterase (PubMed:19439193, PubMed:20418879). Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS (PubMed:20418879). Has depalmitoylating activity toward KCNMA1 (PubMed:22399288). Could also depalmitoylate ADRB2...
Schlagworte: | Anti-APT1, Anti-APT-1, Anti-LPL-I, Anti-hAPT1, Anti-LYPLA1, Anti-LysoPLA I, EC=3.1.2.-, Anti-Lysophospholipase I,... |
Anwendung: | IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 335,00 €
Artikelnummer: ARG44432.50
Protein function: Acts as a acyl-protein thioesterase (PubMed:19439193, PubMed:20418879). Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS (PubMed:20418879). Has depalmitoylating activity toward KCNMA1 (PubMed:22399288). Could also depalmitoylate ADRB2...
Schlagworte: | Anti-APT1, Anti-APT-1, Anti-hAPT1, Anti-LPL-I, Anti-APT-1, Anti-hAPT1, Anti-LPL-I, Anti-LYPLA1, Anti-LysoPLA I,... |
Anwendung: | FC, IHC (paraffin), WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
520,00 €
Artikelnummer: ELK-ES2735.100
This gene encodes a member of the alpha/beta hydrolase superfamily. The encoded protein functions as a homodimer, exhibiting both depalmitoylating as well as lysophospholipase activity, and may be involved in Ras localization and signaling. Alternate splicing results in multiple transcript variants. Pseudogenes of...
Schlagworte: | Anti-APT1, Anti-APT-1, Anti-LPL-I, Anti-hAPT1, Anti-LYPLA1, Anti-LysoPLA I, EC=3.1.2.-, Anti-Lysophospholipase 1,... |
Anwendung: | WB, IHC, IF, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 169,00 €
Artikelnummer: 350053.500
LYPLA1 is lysophospholipase that acts on biological membranes to regulate the multifunctional lysophospholipids. This protein hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS and also has depalmitoylating activity. Source: Recombinant protein...
Schlagworte: | Apt1, LPL-I, APT-1, Lypla1, LysoPLA I, EC=3.1.2.-, Lysophospholipase 1, Lysophospholipase I, Acyl-protein thioesterase 1 |
Ursprungsart: | mouse |
MW: | 26.8 kD |
ab 568,00 €
Artikelnummer: VHPS-5437
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Schlagworte: | APT1, LPL-I, APT-1, hAPT1, LYPLA1, LysoPLA I, EC=3.1.2.-, Lysophospholipase 1, Lysophospholipase I, Acyl-protein... |
Anwendung: | RNA quantification |
43,00 €
Artikelnummer: VMPS-3623
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Schlagworte: | Apt1, APT-1, LPL-I, Lypla1, LysoPLA I, EC=3.1.2.-, Lysophospholipase I, Lysophospholipase 1, Acyl-protein thioesterase 1 |
Anwendung: | RNA quantification |
43,00 €
Artikelnummer: VRPS-3440
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Schlagworte: | Apt1, APT-1, LPL-I, Lypla1, LysoPLA I, EC=3.1.2.-, Lysophospholipase I, Lysophospholipase 1, Acyl-protein thioesterase 1 |
Anwendung: | RNA quantification |
52,00 €
Artikelnummer: 038028-APC.200
Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene hydrolyzes lysophosphatidylcholine in both monomeric and micellar forms. The use of alternate polyadenylation sites has been found for this gene. There are alternatively...
Schlagworte: | Anti-APT1, Anti-LPL-I, Anti-hAPT1, Anti-APT-1, Anti-LYPLA1, Anti-LysoPLA I, EC=3.1.2.-, Anti-Lysophospholipase 1,... |
Anwendung: | FLISA, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
993,00 €