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Anti-ADAM17 (human) (blocking), clone D1(A12)
Anti-ADAM17 (human) (blocking), clone D1(A12)

Artikelnummer: AG-27B-6000PF-C100

Protein function: Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor...
Schlagworte: Anti-CSVP, Anti-ADAM17, Anti-CD156b, Anti-ADAM 17, EC=3.4.24.86, Anti-TNF-alpha convertase, Anti-Snake venom-like...
Anwendung: FA (blocking)
Wirt: Human
Spezies-Reaktivität: human
572,00 €
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Anti-Adam17
Anti-Adam17

Artikelnummer: NSJ-RQ7140

0.5mg/ml if reconstituted with 0.2ml sterile DI water. ADAM17 (ADAM metallopeptidase domain 17), also called TACE (tumor necrosis factor-alpha-converting enzyme), is a 70-kDa enzyme that belongs to the ADAM protein family of disintegrins and metalloproteases. Expression studies showed that the encoded protein...
Schlagworte: Anti-Tace, Anti-Adam17, Anti-CD156b, Anti-ADAM 17, Anti-TNF-alpha convertase, Anti-TNF-alpha-converting enzyme,...
Anwendung: WB, Direct ELISA
Wirt: Rabbit
Spezies-Reaktivität: mouse, rat
755,00 €
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Mouse ADAM17 (A Disintegrin And Metalloprotease 17) ELISA Kit
Mouse ADAM17 (A Disintegrin And Metalloprotease 17) ELISA...

Artikelnummer: ELK-ELK5476.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse ADAM17. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse ADAM17....
Schlagworte: Tace, Adam17, CD156b, ADAM 17, TNF-alpha convertase, TNF-alpha-converting enzyme, Disintegrin and metalloproteinase...
Anwendung: ELISA
Spezies-Reaktivität: mouse
ab 365,00 €
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Rat ADAM17 (A Disintegrin And Metalloprotease 17) ELISA Kit
Rat ADAM17 (A Disintegrin And Metalloprotease 17) ELISA Kit

Artikelnummer: ELK-ELK6759.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat ADAM17. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat ADAM17. Next,...
Schlagworte: Tace, Adam17, CD156b, ADAM 17, TNF-alpha convertase, TNF-alpha-converting enzyme, Disintegrin and metalloproteinase...
Anwendung: ELISA
Spezies-Reaktivität: rat
ab 365,00 €
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Human ADAM17 (A Disintegrin And Metalloprotease 17) ELISA Kit
Human ADAM17 (A Disintegrin And Metalloprotease 17) ELISA...

Artikelnummer: ELK-ELK1317.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human ADAM17. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human ADAM17....
Schlagworte: CSVP, CD156b, ADAM17, ADAM 17, TNF-alpha convertase, Snake venom-like protease, TNF-alpha-converting enzyme, Disintegrin...
Anwendung: ELISA
Spezies-Reaktivität: human
ab 303,00 €
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TAPI-1
TAPI-1

Artikelnummer: Cay18505-500

TNF-alpha converting enzyme (TACE, also known as ADAM17) is a zinc metalloprotease that cleaves the membrane-bound precursor of TNF-alpha to give the mature soluble form of TNF-alpha. It also mediates the proteolytic release of several other cell-surface proteins, including TNF-alpha receptors (TNFRs). TAPI-1, known...
Schlagworte: TAPI, N-[2-[2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-N-(2-aminoethyl)-...
Anwendung: ADAM17 inhibitor
CAS 171235-71-5
MW: 499.6 D
ab 189,00 €
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TAPI-2
TAPI-2

Artikelnummer: Cay14695-1

The extracellular domains of many different types of transmembrane proteins, including growth factors, growth factor receptors and cell adhesion molecules, are proteolytically released (shed) in response to environmental cues. TNF protease inhibitor 2 (TAPI-2) is a broad-spectrum inhibitor of TNF-alpha converting...
Schlagworte: TNF Protease Inhibitor 2,...
Anwendung: TAPI-2 Inhibitor
CAS 187034-31-7
MW: 415.5 D
ab 201,00 €
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TMI-005
TMI-005

Artikelnummer: Cay29016-1

TMI-005 is an inhibitor of disintegrin and metalloproteinase domain-containing protein 17/TNF-alpha converting enzyme (ADAM17/TACE), matrix metalloproteinase-1 (MMP-1), and MMP-13 (IC50s = 20, 33, and 8.1 nM, respectively). It inhibits LPS-induced TNF-alpha release in isolated human whole blood (IC50 = 144 ng/ml)....
Schlagworte: Apratastat, (3S)-N-hydroxy-4-[[4-[(4-hydroxy-2-butyn-1-yl)oxy]phenyl]sulfonyl]-2,2-dimethyl-3-thiomorpholinecarboxamide
Anwendung: ADAM17 / MMP-1 / MMP-13 inhibitor
CAS 287405-51-0
MW: 414.5 D
ab 60,00 €
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Anti-ADAM17 (human), clone D1(A12) (rec.) (blocking) (Fab Fragment) (His)
Anti-ADAM17 (human), clone D1(A12) (rec.) (blocking) (Fab...

Artikelnummer: AG-27B-6003PF-C100

ADAM17 (Disintegrin and metalloproteinase domain-containing protein 17), also called TACE (Tumor necrosis factor-alpha-converting enzyme) is the prototype of the ADAM family of ectodomain shedding proteases (sheddase). ADAM17 is understood to be involved in the processing of TNF-alpha at the surface of the cell and...
Schlagworte: Anti-CSVP, Anti-CD156b, Anti-ADAM17, Anti-ADAM 17, EC=3.4.24.86, Anti-TNF-alpha convertase, Anti-Snake venom-like...
462,00 €
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Anti-TACE / ADAM17
Anti-TACE / ADAM17

Artikelnummer: ARG54323.50

Protein function: Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor...
Schlagworte: Anti-CSVP, Anti-ADAM17, Anti-CD156b, Anti-ADAM 17, EC=3.4.24.86, Anti-TNF-alpha convertase, Anti-Snake venom-like...
Anwendung: WB, ICC, IF
Wirt: Rabbit
Spezies-Reaktivität: human
608,00 €
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Anti-ADAM17 / TACE, C-terminal
Anti-ADAM17 / TACE, C-terminal

Artikelnummer: ARG63476.100

Protein function: Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor...
Schlagworte: Anti-CSVP, Anti-CD156b, Anti-ADAM17, Anti-ADAM 17, EC=3.4.24.86, Anti-TNF-alpha convertase, Anti-Snake venom-like...
Anwendung: ELISA, WB
Wirt: Goat
Spezies-Reaktivität: human
784,00 €
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Human TACE / ADAM17 ELISA Kit
Human TACE / ADAM17 ELISA Kit

Artikelnummer: G-HUFI01209.96

Anwendung: ELISA
Spezies-Reaktivität: human
641,00 €
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