Zu "K06059" wurden 72 Artikel gefunden!
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ADAM17 Fluorescent Assay Kit
Artikelnummer: BPS-78000
The ADAM17 Fluorescent Assay Kit is provided in a convenient 96-well format, with purified ADAM17, ADAM Fluorogenic Substrate, and ADAM assay buffer for 96 enzyme reactions. The key to the ADAM17 Fluorescent Assay Kit is the fluorogenic substrate. Using this kit, only one simple step on a microtiter plate is...
| Schlagworte: | Disintegrin And Metalloproteinase Domain-Containing Protein, Tumor Necrosis Factor, Alpha, Converting Enzyme, Snake... |
| Anwendung: | Enzyme kinetics, drug discovery, HTS |
| Spezies-Reaktivität: | human |
737,00 €
TAPI-1
Artikelnummer: Cay18505-1
TNF-alpha converting enzyme (TACE, also known as ADAM17) is a zinc metalloprotease that cleaves the membrane-bound precursor of TNF-alpha to give the mature soluble form of TNF-alpha. It also mediates the proteolytic release of several other cell-surface proteins, including TNF-alpha receptors (TNFRs). TAPI-1, known...
| Schlagworte: | TAPI, N-[2-[2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-N-(2-aminoethyl)-... |
| Anwendung: | ADAM17 inhibitor |
| CAS | 171235-71-5 |
| MW: | 499.6 D |
ab 221,00 €
TAPI-2
Artikelnummer: Cay14695-1
The extracellular domains of many different types of transmembrane proteins, including growth factors, growth factor receptors and cell adhesion molecules, are proteolytically released (shed) in response to environmental cues. TNF protease inhibitor 2 (TAPI-2) is a broad-spectrum inhibitor of TNF-alpha converting...
| Schlagworte: | TNF Protease Inhibitor 2,... |
| Anwendung: | TAPI-2 Inhibitor |
| CAS | 187034-31-7 |
| MW: | 415.5 D |
ab 223,00 €
TMI-005
Artikelnummer: Cay29016-1
TMI-005 is an inhibitor of disintegrin and metalloproteinase domain-containing protein 17/TNF-alpha converting enzyme (ADAM17/TACE), matrix metalloproteinase-1 (MMP-1), and MMP-13 (IC50s = 20, 33, and 8.1 nM, respectively). It inhibits LPS-induced TNF-alpha release in isolated human whole blood (IC50 = 144 ng/ml)....
| Schlagworte: | Apratastat, (3S)-N-hydroxy-4-[[4-[(4-hydroxy-2-butyn-1-yl)oxy]phenyl]sulfonyl]-2,2-dimethyl-3-thiomorpholinecarboxamide |
| Anwendung: | ADAM17 / MMP-1 / MMP-13 inhibitor |
| CAS | 287405-51-0 |
| MW: | 414.5 D |
ab 67,00 €
Anti-ADAM17 (human), clone D1(A12) (rec.) (blocking) (Fab...
Artikelnummer: AG-27B-6003PF-C100
ADAM17 (Disintegrin and metalloproteinase domain-containing protein 17), also called TACE (Tumor necrosis factor-alpha-converting enzyme) is the prototype of the ADAM family of ectodomain shedding proteases (sheddase). ADAM17 is understood to be involved in the processing of TNF-alpha at the surface of the cell and...
| Schlagworte: | Anti-CSVP, Anti-CD156b, Anti-ADAM17, Anti-ADAM 17, EC=3.4.24.86, Anti-TNF-alpha convertase, Anti-Snake venom-like... |
462,00 €
Anti-TACE / ADAM17
Artikelnummer: ARG54323.50
Protein function: Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor...
| Schlagworte: | Anti-CSVP, Anti-ADAM17, Anti-CD156b, Anti-ADAM 17, EC=3.4.24.86, Anti-TNF-alpha convertase, Anti-Snake venom-like... |
| Anwendung: | WB, ICC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
641,00 €
Anti-ADAM17 / TACE, C-terminal
Artikelnummer: ARG63476.100
Protein function: Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor...
| Schlagworte: | Anti-CSVP, Anti-CD156b, Anti-ADAM17, Anti-ADAM 17, EC=3.4.24.86, Anti-TNF-alpha convertase, Anti-Snake venom-like... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
871,00 €
Human TACE/ADAM17 ELISA Kit
Artikelnummer: G-HUFI01209.96
ELISA Type: Sandwich. Detection Range: 31.25-2000µg/mL. Sensitivity: 18.75µg/mL. Sample Types: Serum, Plasma. Protein function: Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form (PubMed:9034191). Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface...
| Schlagworte: | CSVP, CD156b, ADAM17, ADAM 17, TNF-alpha convertase, Snake venom-like protease, TNF-alpha-converting enzyme, Disintegrin... |
| Anwendung: | Sandwich ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Anti-ADAM17
Artikelnummer: NSJ-R32847
0.5mg/ml if reconstituted with 0.2ml sterile DI water. ADAM17 (ADAM metallopeptidase domain 17), also called TACE (tumor necrosis factor-alpha-converting enzyme), is an enzyme that belongs to the ADAM protein family of disintegrins and metalloproteases. Expression studies showed that the encoded protein cleaves...
| Schlagworte: | Anti-CSVP, Anti-CD156b, Anti-ADAM17, Anti-ADAM 17, Anti-TNF-alpha convertase, Anti-Snake venom-like protease,... |
| Anwendung: | WB, ELISA (direct) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-ADAM17
Artikelnummer: NSJ-R34736-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: A disintegrin and metalloproteinase domain 17, TACE Protein function: Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of...
| Schlagworte: | Anti-CSVP, Anti-ADAM17, Anti-CD156b, Anti-ADAM 17, EC=3.4.24.86, Anti-TNF-alpha convertase, Anti-Snake venom-like... |
| Anwendung: | WB, ELISA (peptide), IHC (paraffin) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €
Anti-ADAM17
Artikelnummer: NSJ-F44300-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. ADAM17 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and...
| Schlagworte: | Anti-CSVP, Anti-ADAM17, Anti-CD156b, Anti-ADAM 17, EC=3.4.24.86, Anti-TNF-alpha convertase, Anti-Snake venom-like... |
| Anwendung: | WB, FC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Anti-ADAM17
Artikelnummer: NSJ-F44301-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75...
| Schlagworte: | Anti-CSVP, Anti-ADAM17, Anti-CD156b, Anti-ADAM 17, EC=3.4.24.86, Anti-TNF-alpha convertase, Anti-Snake venom-like... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €