Zu "K06051" wurden 267 Artikel gefunden!
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DLL3 Knockout SHP-77 Cell Line
Artikelnummer: BPS-83570
DLL3 Knockout SHP-77 Cell line is a human small cell lung cancer (SCLC) cell line, in which DLL3 (Delta-like canonical Notch ligand 3) is not expressed due to CRISPR/Cas9 genome editing. This cell line was validated by flow cytometry. Small cell lung cancer (SCLC), an aggressive form of cancer, accounts for about...
| Schlagworte: | DLL3, Delta-like protein 3, Drosophila Delta homolog 3 |
| Anwendung: | T cell killing assay control, ADC control |
| Spezies-Reaktivität: | human |
6.269,00 €
Anti-Recombinant DLL3, clone A205
Artikelnummer: E-AN301506L.100
Delta-like protein 3 (DLL3), as a ligand of the Notch pathway, is specifically and highly expressed on the surface of SCLC (small cell lung cancer) cells. It plays an important role in tumor initiation, epithelial-mesenchymal transition, invasion and metastasis of SCLC. Inhibits primary neurogenesis. May be required...
| Schlagworte: | Anti-DLL3, Anti-Delta-like protein 3, Anti-Drosophila Delta homolog 3, Recombinant DLL3 Monoclonal Antibody |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 304,00 €
DLL1/Delta1, His, Human
Artikelnummer: GSC-Z05223-100
DLL1, a Notch signaling ligand, is significantly overexpressed in ERalpha luminal breast cancer. Intriguingly, DLL1 overexpression correlates with poor prognosis in ERalpha luminal breast cancer, but not in other subtypes of breast cancer. In addition, this effect is specific to DLL1, as other Notch ligands (DLL3,...
| Schlagworte: | DLL1, Delta-like protein 1, Drosophila Delta homolog 1 |
| Ursprungsart: | human |
| MW: | 57.6 kD |
ab 376,00 €
DLL4, Human
Artikelnummer: GSC-Z03812-100
DLL4 is a type I membrane protein in the Delta/Serrate/Lag2 (DSL) family of Notch ligands. It activates NOTCH1 and NOTCH4, and plays a role in angiogenesis by negatively regulating endothelial cell proliferation and migration, as well as angiogenic sprouting. It is essential for retinal progenitor proliferation and...
| Schlagworte: | DLL4, Delta-like protein 4, Drosophila Delta homolog 4 |
| Ursprungsart: | human |
| MW: | 54.28 kD |
ab 343,00 €
DLL3, His, Human
Artikelnummer: GSC-Z03813-100
DLL3, a transmembrane protein in the Delta/Serrate/Lag-2 (DSL) family of Notch ligands, inhibits primary neurogenesis and helps divert neurons along specific differentiation pathways. It also contributes to the formation of somite boundaries during paraxial mesoderm segmentation.
| Schlagworte: | DLL3, Delta-like protein 3, Drosophila Delta homolog 3 |
| Ursprungsart: | human |
| MW: | 50.4 kD |
ab 504,00 €
Anti-DLL1
Artikelnummer: ATA-HPA040221.100
Rabbit Polyclonal DLL1 Antibody against Human delta like canonical Notch ligand 1. Validated for Western Blot. Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Interspecies information: Highest antigen sequence indentity to the following orthologs: ENSMUSG00000014773: 94%,...
| Schlagworte: | Anti-Delta1, Anti-H-Delta-1, Anti-Delta-like protein 1, Anti-Drosophila Delta homolog 1 |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
DLL4 (human), recombinant protein (His Tag)
Artikelnummer: E-PDMH100443.1
Protein function: Involved in the Notch signaling pathway as Notch ligand (PubMed:11134954). Activates NOTCH1 and NOTCH4. Involved in angiogenesis, negatively regulates endothelial cell proliferation and migration and angiogenic sprouting (PubMed:20616313). Essential for retinal progenitor proliferation. Required...
| Schlagworte: | DLL4, Delta4, Delta-like protein 4, Drosophila Delta homolog 4, Recombinant Human DLL4 Protein(His Tag) |
| Exprimiert in: | Mammalian |
| Ursprungsart: | human |
ab 192,00 €
DLL1 (human):Fc (human) (rec.)
Artikelnummer: AG-40A-0116Y-C010
Signal peptide and extracellular domain of human DLL1 (aa 1-545) are fused at the C-terminus to the Fc portion of human IgG1. Lyophilized. Contains PBS. DLL1 (Delta-like protein, Delta1) is essential for postnatal arteriogenesis and contributes to tumor progression. DLL1 is involved in differentiation and...
| Schlagworte: | DLL1, Delta1, H-Delta-1, Delta-like protein 1, Drosophila Delta homolog |
| Anwendung: | Bioassay |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | human |
| MW: | 100 kD |
ab 253,00 €
DLL1 (human, rec.)
Artikelnummer: AG-40A-0073-C050
Signal peptide and extracellular domain of human DLL1 (amino acids 1-545) are fused at the C-terminus to a FLAG(R)-tag. Inhibits adipogenesis of mesenchymal stem cells. Liquid. 0.2µm-filtered solution in PBS. The Notch ligand delta-like protein 1 (DLL1) is essential for postnatal arteriogenesis and contributes to...
| Schlagworte: | Delta-like Protein 1, Delta1 |
| Anwendung: | Bioassays |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 70 kD |
ab 193,00 €
Anti-DELTA-4
Artikelnummer: 600-401-696
Protein function: Plays a role in the Notch signaling pathway. Activates Notch-1 and Notch-4. [The UniProt Consortium]
| Schlagworte: | Anti-DLL4, Anti-Delta4, Anti-Delta-like protein 4, Anti-Drosophila Delta homolog 4 |
| Anwendung: | ELISA, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
733,00 €
DLL4 (mouse):Fc (human, rec.)
Artikelnummer: AG-40A-0145-C050
Signal peptide and extracellular domain of mouse DLL4 (amino acids 1-532) is fused at the C-terminus to the Fc portion of human IgG1. Inhibits adipogenesis of 3T3L-1 cells. Liquid. 0.2µm-filtered solution in PBS. The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial...
| Schlagworte: | Delta-like Protein 4, Delta4 |
| Anwendung: | Bioassays |
| Exprimiert in: | Human cells |
| Ursprungsart: | mouse |
| MW: | 95 kD |
ab 138,00 €
DLL3 Lentivirus
Artikelnummer: BPS-78909
DLL3 (Delta-like protein 3) Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles ready to transduce nearly all types of mammalian cells, including primary and non-dividing cells. These particles contain human DLL3 (NM_016941.3) driven by a CMV promoter and a puromycin selection...
| Schlagworte: | DLL3, Delta3, Delta-like protein 3, Drosophila Delta homolog 3, |
| Anwendung: | Protein expression, cell pool / stable cell line generation (puromycin selection) |
| Spezies-Reaktivität: | human |
1.490,00 €