Zu "K05871" wurden 76 Artikel gefunden!
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Anti-PTK2B / PYK2 / Protein tyrosine kinase 2 beta
Artikelnummer: NSJ-FY12929
Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. PTK2B antibody detects Protein tyrosine kinase 2 beta, also known as PYK2, a non-receptor tyrosine kinase involved in calcium-dependent signal transduction, cytoskeletal remodeling, and synaptic plasticity. Encoded by the PTK2B gene on...
| Schlagworte: | Anti-PTK2B, Anti-Focal adhesion kinase 2, Anti-Cell adhesion kinase beta, Anti-Proline-rich tyrosine kinase 2,... |
| Anwendung: | WB, IHC, ICC/IF, FC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Defactinib
Artikelnummer: Cay17737-1
Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase that plays a vital role in many oncogenic pathways. Defactinib is a dose-dependent inhibitor of FAK, with maximal inhibition of FAK autophosphorylation in cells achieved at 10 µM. It is less effective against the related kinase PYK2. Defactinib restores...
| Schlagworte: | PF-04554878, VS-6063,... |
| Anwendung: | FAK inhibitor |
| CAS | 1073154-85-4 |
| MW: | 510.5 D |
ab 56,00 €
PF-4618433
Artikelnummer: SYN-1163-M001
Soluble in DMSO. PF-4618433 shows improved PYK2 potency, reduced p38 activity, and superior overall selectivity relative to the prototype BIRB796. In the functional osteogenesis assays, cultures treated with increasing concentrations of PF-4618433 starting at day 1 and maintained throughout showed a dose-dependent...
| Schlagworte: | PF4618433 |
| Anwendung: | PYK2 inhibitor |
| CAS | 1166393-85-6 |
| MW: | 445,5 D |
ab 293,00 €
Anti-phospho-Pyk2 (Tyr402)
Artikelnummer: ARG51707.100
Protein function: Non-receptor protein-tyrosine kinase that regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion, spreading and bone remodeling. Plays a role in the regulation of the humoral immune response, and is required for normal levels of marginal B-cells in the...
| Schlagworte: | Anti-phospho-FAK2, Anti-phospho-CAKB, Anti-phospho-RAFTK, Anti-phospho-CADTK, Anti-phospho-PTK2B, Anti-phospho-FADK 2,... |
| Anwendung: | ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 471,00 €
Anti-Pyk2
Artikelnummer: ARG55580.100
Protein function: Non-receptor protein-tyrosine kinase that regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion, spreading and bone remodeling. Plays a role in the regulation of the humoral immune response, and is required for normal levels of marginal B-cells in the...
| Schlagworte: | Anti-CAKB, Anti-FAK2, Anti-PTK2B, Anti-CADTK, Anti-RAFTK, Anti-FADK 2, Anti-CAK-beta, EC=2.7.10.2, Anti-Focal adhesion... |
| Anwendung: | IHC (paraffin), ICC, IF, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
616,00 €
Anti-Pyk2
Artikelnummer: ARG55619.100
Protein function: Non-receptor protein-tyrosine kinase that regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion, spreading and bone remodeling. Plays a role in the regulation of the humoral immune response, and is required for normal levels of marginal B-cells in the...
| Schlagworte: | Anti-CAKB, Anti-Fak2, Anti-CADTK, Anti-Ptk2b, Anti-RAFTK, Anti-FADK 2, Anti-CAK-beta, EC=2.7.10.2, Anti-Focal adhesion... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse, rat |
616,00 €
Anti-PYK2
Artikelnummer: A304-226A
Protein function: Non-receptor protein-tyrosine kinase that regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion, spreading and bone remodeling. Plays a role in the regulation of the humoral immune response, and is required for normal levels of marginal B-cells in the...
| Schlagworte: | Anti-CAKB, Anti-FAK2, Anti-CADTK, Anti-PTK2B, Anti-RAFTK, Anti-FADK 2, Anti-CAK-beta, EC=2.7.10.2, Anti-Focal adhesion... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-PYK2
Artikelnummer: A304-227A
Protein function: Non-receptor protein-tyrosine kinase that regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion, spreading and bone remodeling. Plays a role in the regulation of the humoral immune response, and is required for normal levels of marginal B-cells in the...
| Schlagworte: | Anti-CAKB, Anti-FAK2, Anti-CADTK, Anti-PTK2B, Anti-RAFTK, Anti-FADK 2, Anti-CAK-beta, EC=2.7.10.2, Anti-Focal adhesion... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
PYK2, active human recombinant protein
Artikelnummer: BPS-40480
Active human PYK2 (GenBank Accession No. U33284), full length with N-terminal His tag, MW=120 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
| Schlagworte: | FAK2, CAKB, RAFTK, PTK2B, CADTK, FADK 2, CAK-beta, EC=2.7.10.2, Focal adhesion kinase 2, Cell adhesion kinase beta,... |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 120 kD |
536,00 €
Defactinib
Artikelnummer: LKT-D1722.100
FAK inhibitor.
| Schlagworte: | VS-6063, PF-04554878 |
| Anwendung: | FAK inhibitor |
| CAS | 1073154-85-4 |
| MW: | 510.49 D |
ab 151,00 €
PF-431396
Artikelnummer: Cay17665-10
Proline-rich tyrosine kinase 2 (PYK2) and focal adhesion kinase (FAK) are nonreceptor tyrosine kinases that constitute the focal adhesion kinase subfamily. PYK2 is expressed in both bone-forming osteoblasts and bone-resorbing osteoclasts where it has a positive role in osteoclast maturation and bone resorption....
| Schlagworte: | N-[2-[[[2-[(2,3-dihydro-2-oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]phenyl]-N-methyl-methane... |
| Anwendung: | FAK / PYK2 inhibitor |
| CAS | 717906-29-1 |
| MW: | 506.5 D |
ab 49,00 €
Anti-PTK2B
Artikelnummer: E-AB-15011.120
This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase...
| Schlagworte: | Anti-CAKB, Anti-FAK2, Anti-PTK2B, Anti-RAFTK, Anti-CADTK, Anti-FADK 2, Anti-CAK-beta, EC=2.7.10.2, Anti-Focal adhesion... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €