Zu "K05854" wurden 65 Artikel gefunden!
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Human LYN (V-Yes-1 Yamaguchi Sarcoma Viral Related...
Artikelnummer: ELK-ELK3494.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human LYN. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human LYN. Next,...
| Schlagworte: | LYN, JTK8, p53Lyn, p56Lyn, EC=2.7.10.2, Tyrosine-protein kinase Lyn, Lck/Yes-related novel protein tyrosine kinase,... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Bafetinib
Artikelnummer: Cay19169-1
Bcr-Abl, a fusion protein with deregulated tyrosine kinase activity, is highly expressed in chronic myelogenous leukemia (CML). Bafetinib is a rationally developed tyrosine kinase inhibitor based on the chemical structure of imatinib (Cay-13139), with modifications added to improve binding and potency against...
| Schlagworte: | INNO-406, NS-187,... |
| Anwendung: | Bcr-Abl tyrosine kinase inhibitor, Lyn tyrosine kinase inhibitor |
| CAS | 859212-16-1 |
| MW: | 576.6 D |
ab 60,00 €
Anti-Lyn, clone LYN-01
Artikelnummer: ARG63066.50
Protein function: Non-receptor tyrosine-protein kinase that transmits signals from cell surface receptors and plays an important role in the regulation of innate and adaptive immune responses, hematopoiesis, responses to growth factors and cytokines, integrin signaling, but also responses to DNA damage and genotoxic...
| Schlagworte: | Anti-LYN, Anti-JTK8, Anti-p56Lyn, Anti-p53Lyn, EC=2.7.10.2, Anti-Tyrosine-protein kinase Lyn, Anti-Lck/Yes-related novel... |
| Anwendung: | IP, WB, ICC, IF |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat |
ab 436,00 €
A-419259 (hydrochloride)
Artikelnummer: Cay18168-10
A-419259 is an inhibitor of Src family kinases, including Src, LCK, Lyn, and Hck (IC50s = 9, 50 = 3,000 nM) and PKC (IC50 = >33 µM). A-419259 inhibits growth of Philadelphia chromosome-positive (Ph+) K-562 and Meg-01 myeloid leukemia cells (IC50s = 0.1-0.3 and 0.1 µM, respectively), but not Ph- TF-1 and HEL cells....
| Schlagworte: | RK-20449, 7-[trans-4-(4-methyl-1-piperazinyl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine,... |
| Anwendung: | Src family kinase ( Src, Lck, Lyn, Hck) inhibitor |
| CAS | 1435934-25-0 |
| MW: | 592 D |
ab 60,00 €
MLR-1023
Artikelnummer: Cay21496-10
MLR-1023 is an allosteric activator of Lyn kinase (EC50 = 63 nM). It has no significant activity against a panel of related kinases. MLR-1023 is orally bioavailable and reduces blood glucose levels in mice subjected to an oral glucose tolerance test. This effect is insulin-dependent, with MLR-1023 increasing insulin...
| Schlagworte: | CP 26,154, NSC 314335, 5-(3-methylphenoxy)-2(1H)-pyrimidinone |
| Anwendung: | Allosteric Lyn kinase activator |
| CAS | 41964-07-2 |
| MW: | 202.2 D |
ab 68,00 €
Anti-LYN, Internal
Artikelnummer: ARG64573.100
Protein function: Non-receptor tyrosine-protein kinase that transmits signals from cell surface receptors and plays an important role in the regulation of innate and adaptive immune responses, hematopoiesis, responses to growth factors and cytokines, integrin signaling, but also responses to DNA damage and genotoxic...
| Schlagworte: | Anti-LYN, Anti-JTK8, Anti-p53Lyn, Anti-p56Lyn, EC=2.7.10.2, Anti-Tyrosine-protein kinase Lyn, Anti-Lck/Yes-related novel... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
784,00 €
Anti-LYN
Artikelnummer: A302-683A
LYN is a tyrosine protein kinase that acts as an effector of EpoR (erythropoietin receptor) in controlling KIT expression and may play a central role in erythroid differentiation during the switch between proliferation and maturation. LYN acts as the mediator that relays suppressing signals from the chemokine...
| Schlagworte: | Anti-Tyrosine-protein kinase |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
LYNB, active human recombinant protein
Artikelnummer: BPS-40472
Active recombinant full-length human LYN B was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag. The gene accession number is BC059394.
| Schlagworte: | LYN, JTK8, p53Lyn, p56Lyn, EC=2.7.10.2, Tyrosine-protein kinase Lyn, Lck/Yes-related novel protein tyrosine kinase,... |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 85 kD |
862,00 €
Anti-LYN (C-Terminal Region)
Artikelnummer: NSJ-R32899
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Tyrosine-protein kinase Lyn is a protein that in humans is encoded in humans by the LYN gene. It is mapped to 8q12.1. Lyn is a member of the Src family of protein tyrosine kinases. In various hematopoietic cells, Lyn has emerged as a key enzyme involved in the...
| Schlagworte: | Anti-LYN, Anti-JTK8, Anti-p53Lyn, Anti-p56Lyn, EC=2.7.10.2, Anti-Tyrosine-protein kinase Lyn, Anti-Lck/Yes-related novel... |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
755,00 €
Anti-LYN
Artikelnummer: NSJ-R34674-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: V-yes-1 Yamaguchi sarcoma viral related oncogene, LYN Protein function: Non-receptor tyrosine-protein kinase that transmits signals from cell surface receptors and plays an important role in the...
| Schlagworte: | Anti-LYN, Anti-JTK8, Anti-p56Lyn, Anti-p53Lyn, EC=2.7.10.2, Anti-Tyrosine-protein kinase Lyn, Anti-Lck/Yes-related novel... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
755,00 €
Anti-Lyn
Artikelnummer: NSJ-F44015-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Lyn acts as a positive regulator of cell movement while negatively regulating adhesion to stromal cells by inhibiting the ICAM-1-binding activity of beta-2 integrins. Acts as the mediator that relays suppressing signals from the chemokine receptor CXCR4 to beta-2 integrin...
| Schlagworte: | Anti-Lyn, Anti-p56Lyn, Anti-p53Lyn, EC=2.7.10.2, Anti-Tyrosine-protein kinase Lyn, Anti-V-yes-1 Yamaguchi sarcoma viral... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse |
ab 326,00 €
Anti-Lyn
Artikelnummer: NSJ-F52727-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Non-receptor tyrosine-protein kinase that transmits signals from cell surface receptors and plays an important role in the regulation of innate and adaptive immune responses, hematopoiesis, responses to growth factors and cytokines, integrin signaling, but also responses...
| Schlagworte: | Anti-Lyn, Anti-p56Lyn, Anti-p53Lyn, EC=2.7.10.2, Anti-Tyrosine-protein kinase Lyn, Anti-V-yes-1 Yamaguchi sarcoma viral... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 326,00 €