Zu "K05853" wurden 96 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
Thapsigargin
Artikelnummer: Cay10522-1
Thapsigargin is an inhibitor of sarcoplasmic/endoplasmic reticulum Ca2+-ATPase (SERCA, IC50 = ~30 nM for the rat liver microsomal enzyme), an ER stress inducer, and a sesquiterpene lactone that has been found in Thapsia. It increases intracellular calcium levels in isolated rat hepatocytes (EC50 = ~80 nM) and...
| Schlagworte: | (3S,3aS,4R,6R,7S,8R)-6-acetoxy-4-(butyryloxy)-3,3a-dihydroxy-3,6,9-trimethyl-8-(((Z)-2-methylbut-2-enoyl)oxy)-2-oxo-2,3,3a... |
| Anwendung: | SERCA inhibitor |
| CAS | 67526-95-8 |
| MW: | 650.8 D |
ab 89,00 €
Thapsigargin (high purity)
Artikelnummer: AG-CN2-0003-M001
Colorless to white amorphous powder. Soluble in DMSO or 100% ethanol. Chemical. CAS: 67526-95-8. Formula: C34H50O12. MW: 650.8. Isolated from Thapsia garganica. Intracellular Ca2+ signaling probe. Specific and sensitive inhibitor of SERCA. Non-TPA/PMA tumor promoter. Histamine release inducer. Apoptosis inducer....
| Anwendung: | SERCA inhibitor, Ca2+ releaser |
| CAS | 67526-95-8 |
| MW: | 650,8 D |
ab 55,00 €
Anti-Recombinant SERCA2, clone 6B4
Artikelnummer: E-AN301264L.100
This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in...
| Schlagworte: | Anti-ATP2A2, Anti-Calcium pump 2, Anti-Endoplasmic reticulum class 1/2 Ca(2+) ATPase, Anti-Sarcoplasmic/endoplasmic... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 258,00 €
Cyclopiazonic Acid
Artikelnummer: Cay11326-1
Cyclopiazonic acid is a mycotoxin that has been found in Penicillium and Aspergillus and an inhibitor of sarcoplasmic/endoplasmic reticulum Ca2+-ATPase (SERCA, IC50 = 0.6 µM). In vivo, cyclopiazonic acid (11-14 mg/kg) induces ptosis, hypothermia, tremor, and cachexia, as well as induces lethality (LD50 = 13 mg/kg),...
| Schlagworte: | CPA, NSC 117181,... |
| Anwendung: | SERCA inhibitor, mycotoxin |
| CAS | 18172-33-3 |
| MW: | 336.4 D |
ab 38,00 €
CDN1163
Artikelnummer: Cay31123-1
CDN1163 is an allosteric activator of sarcoplasmic/endoplasmic reticulum Ca2+-ATPase 2 (SERCA2) that enhances calcium uptake in endoplasmic reticulum (ER) vesicles when used at concentrations ranging from 1 to 10 µM. It decreases peroxide-induced cell death in HEK293 cells. CDN1163 (50 mg/kg) increases calcium...
| Schlagworte: | 4-(1-methylethoxy)-N-(2-methyl-8-quinolinyl)-benzamide |
| Anwendung: | Allosteric SERCA2 activator |
| CAS | 892711-75-0 |
| MW: | 320.4 D |
ab 49,00 €
Thapsigargin
Artikelnummer: LKT-T2801.5
Thapsigargin is isolated from Thapsia garganica. It is a cell permeable intracellular calcium releaser and tumor promoter.
| Schlagworte: | Thapsigargine, Tg |
| Anwendung: | SERCA inhibitor, Ca releaser |
| CAS | 67526-95-8 |
| MW: | 650,75 D |
ab 177,00 €
Anti-SERCA2
Artikelnummer: A300-406A
Protein function: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Isoform 2 is involved in the regulation of the contraction/relaxation cycle (PubMed:16402920). Acts as a regulator of TNFSF11-mediated...
| Schlagworte: | Anti-ATP2B, Anti-SERCA2, Anti-ATP2A2, EC=3.6.3.8, Anti-Calcium pump 2, Anti-SR Ca(2+)-ATPase 2, Anti-Endoplasmic reticulum... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Cyclopiazonic acid
Artikelnummer: LKT-C9809.5
An inhibitor of the sarco/endoplasmic reticulum calcium pump that has produced hypokinesia, hypothermia, catalepsy, ptosis, and sedation without loss of righting reflex, tremor, gait disturbance, dyspnoea, opisthotonus, atypical convulsion, and prolonged barbiturate-induced sleep in mice.
| Schlagworte: | CPA |
| Anwendung: | Calcium pump inhibitor |
| CAS | 18172-33-3 |
| MW: | 336,39 D |
ab 231,00 €
Human SERCA3 / Sarcoplasmic / endoplasmic reticulum...
Artikelnummer: G-HUFI02100.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Anti-ATP2A1
Artikelnummer: NSJ-R30155
0.5mg/ml if reconstituted with 0.2ml sterile DI water. SERCA1, also called ATP2A1, is an enzyme that in humans is encoded by the ATP2A1 gene. This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. The SERCA1 gene is mapped...
| Schlagworte: | Anti-ATP2A1, Anti-SERCA1, EC=3.6.3.8, Anti-Calcium pump 1, Anti-SR Ca(2+)-ATPase 1, Anti-Endoplasmic reticulum class 1/2... |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-ATP2A2
Artikelnummer: NSJ-R30156
0.5mg/ml if reconstituted with 0.2ml sterile DI water. SERCA2, also called ATP2A2 or ATP2B, encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. They are closely related to the plasma membrane Ca(2+)-ATPases, or PMCAs. SERCA2...
| Schlagworte: | Anti-ATP2B, Anti-ATP2A2, Anti-SERCA2, EC=3.6.3.8, Anti-Calcium pump 2, Anti-SR Ca(2+)-ATPase 2, Anti-Endoplasmic reticulum... |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-ATP2A3
Artikelnummer: NSJ-R30157
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Sarcoplasmic/endoplasmic reticulum calcium ATPase 3, also known as SERCA3, is anenzyme that in humans is encoded by the ATP2A3 gene. It is mapped to 17p13.2. This gene encodes one of the SERCA Ca2+-ATPases, which are intracellular pumps located in the...
| Schlagworte: | Anti-ATP2A3, Anti-SERCA3, EC=3.6.3.8, Anti-Calcium pump 3, Anti-SR Ca(2+)-ATPase 3, Anti-Sarcoplasmic/endoplasmic... |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €