Zu "K05853" wurden 66 Artikel gefunden!
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Thapsigargin
Artikelnummer: Cay10522-1
Thapsigargin is an inhibitor of sarcoplasmic/endoplasmic reticulum Ca2+-ATPase (SERCA, IC50 = ~30 nM for the rat liver microsomal enzyme), an ER stress inducer, and a sesquiterpene lactone that has been found in Thapsia. It increases intracellular calcium levels in isolated rat hepatocytes (EC50 = ~80 nM) and...
| Schlagworte: | (3S,3aS,4R,6R,7S,8R)-6-acetoxy-4-(butyryloxy)-3,3a-dihydroxy-3,6,9-trimethyl-8-(((Z)-2-methylbut-2-enoyl)oxy)-2-oxo-2,3,3a... |
| Anwendung: | SERCA inhibitor |
| CAS | 67526-95-8 |
| MW: | 650.8 D |
ab 94,00 €
Thapsigargin (high purity)
Artikelnummer: AG-CN2-0003-M001
Colorless to white amorphous powder. Soluble in DMSO or 100% ethanol. Chemical. CAS: 67526-95-8. Formula: C34H50O12. MW: 650.8. Isolated from Thapsia garganica. Intracellular Ca2+ signaling probe. Specific and sensitive inhibitor of SERCA. Non-TPA/PMA tumor promoter. Histamine release inducer. Apoptosis inducer....
| Anwendung: | SERCA inhibitor, Ca2+ releaser |
| CAS | 67526-95-8 |
| MW: | 650,8 D |
ab 77,00 €
Mouse ATP2A2 (ATPase, Ca++ Transporting, Cardiac Muscle,...
Artikelnummer: ELK-ELK6340.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse ATP2A2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse ATP2A2....
| Schlagworte: | SERCA2, Calcium pump 2, SR Ca(2+)-ATPase 2, Endoplasmic reticulum class 1/2 Ca(2+) ATPase, Sarcoplasmic/endoplasmic... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 365,00 €
Human ATP2A2 (ATPase, Ca++ Transporting, Cardiac Muscle,...
Artikelnummer: ELK-ELK3283.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human ATP2A2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human ATP2A2....
| Schlagworte: | ATP2B, SERCA2, Calcium pump 2, SR Ca(2+)-ATPase 2, Endoplasmic reticulum class 1/2 Ca(2+) ATPase, Sarcoplasmic/endoplasmic... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Rat ATP2A2 (ATPase, Ca++ Transporting, Cardiac Muscle,...
Artikelnummer: ELK-ELK7804.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat ATP2A2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat ATP2A2. Next,...
| Schlagworte: | SERCA2, Atp2a2, EC=7.2.2.10, Calcium pump 2, SR Ca(2+)-ATPase 2, Endoplasmic reticulum class 1/2 Ca(2+) ATPase,... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
ab 365,00 €
Cyclopiazonic Acid
Artikelnummer: Cay11326-1
Cyclopiazonic acid is a mycotoxin that has been found in Penicillium and Aspergillus and an inhibitor of sarcoplasmic/endoplasmic reticulum Ca2+-ATPase (SERCA, IC50 = 0.6 µM). In vivo, cyclopiazonic acid (11-14 mg/kg) induces ptosis, hypothermia, tremor, and cachexia, as well as induces lethality (LD50 = 13 mg/kg),...
| Schlagworte: | CPA, NSC 117181,... |
| Anwendung: | SERCA inhibitor, Mycotoxin |
| CAS | 18172-33-3 |
| MW: | 336.4 D |
ab 34,00 €
Thapsigargin
Artikelnummer: LKT-T2801.5
Thapsigargin is isolated from Thapsia garganica. It is a cell permeable intracellular calcium releaser and tumor promoter.
| Schlagworte: | Thapsigargine, Tg |
| Anwendung: | SERCA inhibitor, Ca releaser |
| CAS | 67526-95-8 |
| MW: | 650,75 D |
ab 169,00 €
Anti-SERCA2
Artikelnummer: A300-406A
Protein function: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Isoform 2 is involved in the regulation of the contraction/relaxation cycle (PubMed:16402920). Acts as a regulator of TNFSF11-mediated...
| Schlagworte: | Anti-ATP2B, Anti-SERCA2, Anti-ATP2A2, EC=3.6.3.8, Anti-Calcium pump 2, Anti-SR Ca(2+)-ATPase 2, Anti-Endoplasmic reticulum... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Cyclopiazonic acid
Artikelnummer: LKT-C9809.5
An inhibitor of the sarco/endoplasmic reticulum calcium pump that has produced hypokinesia, hypothermia, catalepsy, ptosis, and sedation without loss of righting reflex, tremor, gait disturbance, dyspnoea, opisthotonus, atypical convulsion, and prolonged barbiturate-induced sleep in mice.
| Schlagworte: | CPA |
| Anwendung: | Calcium pump inhibitor |
| CAS | 18172-33-3 |
| MW: | 336,39 D |
ab 221,00 €
CDN1163
Artikelnummer: Cay31123-1
CDN1163 is an allosteric activator of sarcoplasmic/endoplasmic reticulum Ca2+-ATPase 2 (SERCA2) that enhances calcium uptake in endoplasmic reticulum (ER) vesicles when used at concentrations ranging from 1 to 10 µM. It decreases peroxide-induced cell death in HEK293 cells. CDN1163 (50 mg/kg) increases calcium...
| Schlagworte: | 4-(1-methylethoxy)-N-(2-methyl-8-quinolinyl)-benzamide |
| Anwendung: | Allosteric SERCA2 activator |
| CAS | 892711-75-0 |
| MW: | 320.4 D |
ab 43,00 €
Anti-SERCA2 ATPase
Artikelnummer: ARG10653.50
Protein function: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Isoform 2 is involved in the regulation of the contraction/relaxation cycle (PubMed:16402920). Acts as a regulator of TNFSF11-mediated...
| Schlagworte: | Anti-ATP2B, Anti-ATP2A2, Anti-SERCA2, EC=3.6.3.8, Anti-Calcium pump 2, Anti-SR Ca(2+)-ATPase 2, Anti-Endoplasmic reticulum... |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
528,00 €
Human SERCA3 / Sarcoplasmic / endoplasmic reticulum...
Artikelnummer: G-HUFI02100.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
641,00 €