Zu "K05849" wurden 43 Artikel gefunden!
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KB-R7943 (mesylate)
Artikelnummer: Cay16352-10
The Na+/Ca2+ exchanger (NCX) is a major regulator of intracellular calcium concentration that is largely expressed in cardiac sarcolemma (NCX1) but also in brain and skeletal muscle (NCX2). KB-R7943 is an isothiourea derivative that selectively inhibits the reverse mode of NCX1 (IC50 = 1.2-2.4 µM), preventing...
| Schlagworte: | 2-[4-[(4-nitrophenyl)methoxy]phenyl]ethyl ester carbamimidothioic acid, monomethanesulfonate |
| Anwendung: | NCX1 inhibitor |
| CAS | 182004-65-5 |
| MW: | 427.5 D |
ab 73,00 €
SN-6
Artikelnummer: Cay42390-10
An NCX1 inhibitor (IC50 = 2.9 µM), selective for NCX1 over NCX2, NCX3, and NCKX2 (IC50s = 16, 8.6, and >30 µM, respectively) and a panel of 26 additional ion channels and receptors at 30 µM, inhibits bidirectional inward and outward currents and unidirectional outward currents in whole-cell voltage-clamp assays...
| Schlagworte: | 2-[[4-[(4-nitrophenyl)methoxy]phenyl]methyl]-4-thiazolidinecarboxylic acid, ethyl ester |
| Anwendung: | NCX1 inhibitor |
| CAS | 415697-08-4 |
| MW: | 402.47 D |
ab 119,00 €
SEA0400
Artikelnummer: Cay19876-1
SEA0400 is a selective inhibitor of the Na+/Ca2+ exchanger (IC50s = 5, 8.3, and 33 nM for inhibiting Na+-dependent Ca2+ uptake in rat astrocyte, microglia, and cortical neuron cell lines, respectively). It is reported to prevent dopaminergic neurotoxicity in an MPTP mouse model of Parkinson's disease and to...
| Schlagworte: | 2-[4-[(2,5-difluorophenyl)methoxy]phenoxy]-5-ethoxy-benzenamine |
| Anwendung: | Selective Na+/Ca2+ exchanger inhibitor |
| CAS | 223104-29-8 |
| MW: | 371.4 D |
ab 73,00 €
Human SLC8A1 / Sodium / calcium exchanger 1 ELISA Kit
Artikelnummer: G-HUFI00617.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Anti-SLC8A3
Artikelnummer: E-AB-13657.120
This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular...
| Schlagworte: | Anti-NCX3, Anti-SLC8A3, Anti-Sodium/calcium exchanger 3, Anti-Na(+)/Ca(2+)-exchange protein 3, Anti-Solute carrier family... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
ab 89,00 €
Anti-SLC8A3
Artikelnummer: E-AB-12798.120
This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Three mammalian isoforms in family 8 have been identified. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and...
| Schlagworte: | Anti-NCX3, Anti-SLC8A3, Anti-Sodium/calcium exchanger 3, Anti-Na(+)/Ca(2+)-exchange protein 3, Anti-Solute carrier family... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 89,00 €
Anti-SLC8A3
Artikelnummer: E-AB-15997.120
This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Three mammalian isoforms in family 8 have been identified. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and...
| Schlagworte: | Anti-NCX3, Anti-SLC8A3, Anti-Sodium/calcium exchanger 3, Anti-Na(+)/Ca(2+)-exchange protein 3, Anti-Solute carrier family... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 89,00 €
Anti-SLC8A3
Artikelnummer: E-AB-16847.120
This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular...
| Schlagworte: | Anti-NCX3, Anti-SLC8A3, Anti-Sodium/calcium exchanger 3, Anti-Na(+)/Ca(2+)-exchange protein 3, Anti-Solute carrier family... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
ab 89,00 €
Anti-SLC8A2
Artikelnummer: ATA-HPA050818.100
Protein function: Mediates the electrogenic exchange of Ca(2+) against Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes. Contributes to cellular Ca(2+) homeostasis in excitable cells. Contributes to the rapid decrease...
| Schlagworte: | Anti-SLC8A2, Anti-KIAA1087, Anti-Sodium/calcium exchanger 2, Anti-Na(+)/Ca(2+)-exchange protein 2, Anti-Solute carrier... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 246,00 €
Anti-SLC8A2
Artikelnummer: ATA-HPA054671.100
Protein function: Mediates the electrogenic exchange of Ca(2+) against Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes. Contributes to cellular Ca(2+) homeostasis in excitable cells. Contributes to the rapid decrease...
| Schlagworte: | Anti-SLC8A2, Anti-KIAA1087, Anti-Sodium/calcium exchanger 2, Anti-Na(+)/Ca(2+)-exchange protein 2, Anti-Solute carrier... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 246,00 €
Anti-SLC8A1
Artikelnummer: ATA-HPA070007.100
Protein function: Mediates the exchange of one Ca(2+) ion against three to four Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes (PubMed:1374913, PubMed:11241183, PubMed:1476165). Contributes to Ca(2+) transport during...
| Schlagworte: | Anti-SLC8A1, Anti-Sodium/calcium exchanger 1, Anti-Na(+)/Ca(2+)-exchange protein 1, Anti-Solute carrier family 8 member 1 |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 246,00 €
Sodium/calcium exchanger 1 (SLC8A1), partial, human,...
Artikelnummer: CSB-YP021723HU.1
Organism: Homo sapiens (Human). Source: Yeast. Expression Region: 396-627aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: VNTEVTENDP VSKIFFEQGT YQCLENCGTV ALTIIRRGGD LTNTVFVDFR TEDGTANAGS DYEFTEGTVV FKPGDTQKEI RVGIIDDDIF EEDENFLVHL SNVKVSSEAS EDGILEANHV STLACLGSPS TATVTIFDDD...
| Schlagworte: | SLC8A1, Sodium/calcium exchanger 1, Na(+)/Ca(2+)-exchange protein 1, Solute carrier family 8 member 1, Recombinant Human... |
| Anwendung: | Activity not tested |
| Exprimiert in: | Yeast |
| Ursprungsart: | human |
| MW: | 27.4 kD |
ab 292,00 €