Zu "K05770" wurden 46 Artikel gefunden!
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TSPO Protein, Pig, Recombinant (His & Myc & SUMO)
Artikelnummer: TGM-TMPH-03128-10ug
Description: Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Can bind protoporphyrin IX and may play a role in the transport of porphyrins...
| Schlagworte: | Translocator protein , TSPO , Peripheral-type benzodiazepine receptor (PBR) , BZRP |
| MW: | 38.6 kD |
ab 497,00 €
TSPO Protein, Mouse, Recombinant (His)
Artikelnummer: TGM-TMPH-04349-100ug
Description: TSPO Protein, Mouse, Recombinant (His) is expressed in in vitro E. coli expression system with N-10xHis. The accession number is P50637.
| Schlagworte: | Mitochondrial benzodiazepine receptor , Translocator protein , Tspo , Mbr , PKBS , Peripheral-type benzodiazepine receptor... |
| MW: | 21.7 kD |
ab 491,00 €
FGIN-1-43
Artikelnummer: Cay42245-10
A translocator protein ligand, binds to translocator protein in a cell-free assay (Ki = 3.6 nM), enhances pregnenolone synthesis in C6 rat glioma cells (EC50 = 10 nM). Formulation: A solid. InChI:...
| Schlagworte: | 5-chloro-2-(4-chlorophenyl)-N,N-dihexyl-1H-indole-3-acetamide |
| Anwendung: | Translocator protein (TSPO) ligand |
| CAS | 145040-29-5 |
| MW: | 487.5 D |
ab 91,00 €
PK11195
Artikelnummer: Cay10525-10
Benzodiazepines bind two types of receptors, the central gamma-aminobutyric acid A receptor and the peripheral translocator protein (TSPO). PK11195 binds the peripheral benzodiazepine receptor, TSPO, with selectivity and high affinity (Ki = 3.1 nM in cerebellum, 4.1 nM in spinal cord). PK11195, which lacks the...
| Schlagworte: | RP 52028, 1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide |
| Anwendung: | TSPO blocking, TSPO detection |
| CAS | 85532-75-8 |
| MW: | 352.9 D |
ab 126,00 €
Anti-TSPO / PBR (isoform), C-terminal
Artikelnummer: ARG64025.100
Protein function: Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism (PubMed:24814875), but its precise physiological role is controversial. It is apparently not required...
| Schlagworte: | Anti-PBR, Anti-PKBS, Anti-BZRP, Anti-TSPO, Anti-Translocator protein, Anti-Mitochondrial benzodiazepine receptor,... |
| Anwendung: | ELISA, IHC (paraffin), WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
871,00 €
Anti-PBR, C-terminal
Artikelnummer: ARG64874.100
Protein function: Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Was initially identified as peripheral-type benzodiazepine receptor, can also bind isoquinoline carboxamides. Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid...
| Schlagworte: | Anti-PBR, Anti-Bzrp, Anti-PKBS, Anti-Tspo, Anti-Translocator protein, Anti-Mitochondrial benzodiazepine receptor,... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | mouse |
871,00 €
Mouse Translocator protein / Tspo ELISA Kit
Artikelnummer: G-MOFI00416.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
698,00 €
Anti-TSPO
Artikelnummer: NSJ-R35565-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Translocator protein (18kDa), PBR, peripheral benzodiazepine receptor Protein function: Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Promotes the...
| Schlagworte: | Anti-PBR, Anti-BZRP, Anti-TSPO, Anti-PKBS, Anti-Translocator protein, Anti-Mitochondrial benzodiazepine receptor,... |
| Anwendung: | WB, IHC, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €
Anti-Pbr
Artikelnummer: NSJ-R35566-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Peripheral benzodiazepine receptor, translocator protein (18kDa), Tspo Protein function: Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Was initially...
| Schlagworte: | Anti-PBR, Anti-Bzrp, Anti-PKBS, Anti-Tspo, Anti-Translocator protein, Anti-Mitochondrial benzodiazepine receptor,... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | mouse |
836,00 €
PK 11195
Artikelnummer: AG-CR1-0008-M010
Selective peripheral benzodiazepine antagonist, Apoptosis enhancer, Glucose-induced insulin secretion inhibitor, Induces mitochondria cytochrome c release, Anticancer compound, Antiproliferative, Pharmacological tool in autophagy.
| Schlagworte: | 1-(2-Chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide |
| Anwendung: | Benzodiazepine antagonist, Apoptosis enhancer |
| CAS | 85532-75-8 |
| MW: | 352,9 D |
ab 61,00 €
AWD 131-138
Artikelnummer: Cay16235-10
AWD 131-138 is a partial agonist of the GABAA receptor that acts at the benzodiazepine binding site, dose-dependently stimulating GABA currents with a threshold of 0.3-1.0 µM. This effect is blocked by the benzodiazepine antagonist flumazenil (Cay-14252). AWD 131-138 displays a broad spectrum of anticonvulsant...
| Schlagworte: | ELB138, Imepitoin, 1-(4-chlorophenyl)-1,5-dihydro-4-(4-morpholinyl)-2H-imidazol-2-one |
| Anwendung: | Partial benzodiazepine receptor agonist |
| CAS | 188116-07-6 |
| MW: | 279.7 D |
ab 164,00 €
AC-5216
Artikelnummer: Cay18522-1
AC-5216 is a high affinity agonist of the 18 kDa translocator protein (TSPO, previously called the peripheral benzodiazepine receptor) that exhibits a Ki value of 0.297 nM in rat whole brain and IC50 values of 2.73 and 3.04 nM, respectively, against human and rat glial TSPO. AC-5216 produces anxiolytic and...
| Schlagworte: | Emapunil, XBD-173, N-ethyl-7,8-dihydro-7-methyl-8-oxo-2-phenyl-N-(phenylmethyl)-9H-purine-9-acetamide |
| Anwendung: | TSPO agonist |
| CAS | 226954-04-7 |
| MW: | 401.5 D |
ab 54,00 €