Zu "K05770" wurden 47 Artikel gefunden!
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TSPO Ligand-1
Artikelnummer: Cay45402-10
TSPO ligand-1 is an intermediate in the synthesis of 2-phenylindolglyoxylamide derivatives that bind translocator protein, formerly known as translocator protein (18 kDa) (TSPO). It has been used in the synthesis of fluorescent probes that are selective for translocator protein. TSPO ligand-1 has also been used in...
| Schlagworte: | Translocator Protein Ligand-1, alpha-oxo-2-phenyl-1H-indole-3-acetyl chloride |
| Anwendung: | 2-phenylindolglyoxylamide derivative intermediate, TSPO binding |
| CAS | 4560-08-1 |
| MW: | 283.71 D |
ab 64,00 €
TSPO Protein, Pig, Recombinant (His & Myc & SUMO)
Artikelnummer: TGM-TMPH-03128-10ug
Description: Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Can bind protoporphyrin IX and may play a role in the transport of porphyrins...
| Schlagworte: | Translocator protein , TSPO , Peripheral-type benzodiazepine receptor (PBR) , BZRP |
| MW: | 38.6 kD |
ab 497,00 €
TSPO Protein, Mouse, Recombinant (His)
Artikelnummer: TGM-TMPH-04349-100ug
Description: TSPO Protein, Mouse, Recombinant (His) is expressed in in vitro E. coli expression system with N-10xHis. The accession number is P50637.
| Schlagworte: | Mitochondrial benzodiazepine receptor , Translocator protein , Tspo , Mbr , PKBS , Peripheral-type benzodiazepine receptor... |
| MW: | 21.7 kD |
ab 491,00 €
PK11195
Artikelnummer: Cay10525-10
Benzodiazepines bind two types of receptors, the central gamma-aminobutyric acid A receptor and the peripheral translocator protein (TSPO). PK11195 binds the peripheral benzodiazepine receptor, TSPO, with selectivity and high affinity (Ki = 3.1 nM in cerebellum, 4.1 nM in spinal cord). PK11195, which lacks the...
| Schlagworte: | RP 52028, 1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide |
| Anwendung: | TSPO blocking, TSPO detection |
| CAS | 85532-75-8 |
| MW: | 352.9 D |
ab 126,00 €
Anti-TSPO / PBR (isoform), C-terminal
Artikelnummer: ARG64025.100
Protein function: Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism (PubMed:24814875), but its precise physiological role is controversial. It is apparently not required...
| Schlagworte: | Anti-PBR, Anti-PKBS, Anti-BZRP, Anti-TSPO, Anti-Translocator protein, Anti-Mitochondrial benzodiazepine receptor,... |
| Anwendung: | ELISA, IHC (paraffin), WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
871,00 €
Anti-PBR, C-terminal
Artikelnummer: ARG64874.100
Protein function: Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Was initially identified as peripheral-type benzodiazepine receptor, can also bind isoquinoline carboxamides. Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid...
| Schlagworte: | Anti-PBR, Anti-Bzrp, Anti-PKBS, Anti-Tspo, Anti-Translocator protein, Anti-Mitochondrial benzodiazepine receptor,... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | mouse |
871,00 €
Mouse Translocator protein / Tspo ELISA Kit
Artikelnummer: G-MOFI00416.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
698,00 €
Anti-TSPO
Artikelnummer: NSJ-R35565-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Translocator protein (18kDa), PBR, peripheral benzodiazepine receptor Protein function: Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Promotes the...
| Schlagworte: | Anti-PBR, Anti-BZRP, Anti-TSPO, Anti-PKBS, Anti-Translocator protein, Anti-Mitochondrial benzodiazepine receptor,... |
| Anwendung: | WB, IHC, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €
Anti-Pbr
Artikelnummer: NSJ-R35566-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Peripheral benzodiazepine receptor, translocator protein (18kDa), Tspo Protein function: Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Was initially...
| Schlagworte: | Anti-PBR, Anti-Bzrp, Anti-PKBS, Anti-Tspo, Anti-Translocator protein, Anti-Mitochondrial benzodiazepine receptor,... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | mouse |
836,00 €
PK 11195
Artikelnummer: AG-CR1-0008-M010
Selective peripheral benzodiazepine antagonist, Apoptosis enhancer, Glucose-induced insulin secretion inhibitor, Induces mitochondria cytochrome c release, Anticancer compound, Antiproliferative, Pharmacological tool in autophagy.
| Schlagworte: | 1-(2-Chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide |
| Anwendung: | Benzodiazepine antagonist, Apoptosis enhancer |
| CAS | 85532-75-8 |
| MW: | 352,9 D |
ab 61,00 €
AWD 131-138
Artikelnummer: Cay16235-10
AWD 131-138 is a partial agonist of the GABAA receptor that acts at the benzodiazepine binding site, dose-dependently stimulating GABA currents with a threshold of 0.3-1.0 µM. This effect is blocked by the benzodiazepine antagonist flumazenil (Cay-14252). AWD 131-138 displays a broad spectrum of anticonvulsant...
| Schlagworte: | ELB138, Imepitoin, 1-(4-chlorophenyl)-1,5-dihydro-4-(4-morpholinyl)-2H-imidazol-2-one |
| Anwendung: | Partial benzodiazepine receptor agonist |
| CAS | 188116-07-6 |
| MW: | 279.7 D |
ab 164,00 €
AC-5216
Artikelnummer: Cay18522-1
AC-5216 is a high affinity agonist of the 18 kDa translocator protein (TSPO, previously called the peripheral benzodiazepine receptor) that exhibits a Ki value of 0.297 nM in rat whole brain and IC50 values of 2.73 and 3.04 nM, respectively, against human and rat glial TSPO. AC-5216 produces anxiolytic and...
| Schlagworte: | Emapunil, XBD-173, N-ethyl-7,8-dihydro-7-methyl-8-oxo-2-phenyl-N-(phenylmethyl)-9H-purine-9-acetamide |
| Anwendung: | TSPO agonist |
| CAS | 226954-04-7 |
| MW: | 401.5 D |
ab 54,00 €