Zu "K05743" wurden 44 Artikel gefunden!
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TH263
Artikelnummer: Cay37295-10
TH263 is an inactive analog of the inhibitor of LIM kinase 1 (LIMK1) and LIMK2 TH257 (Cay-34236) that has been used as a negative control for the kinase activity of LIMK1 and LIMK2.Formal Name: N-(phenylmethyl)-4-[[(phenylmethyl)amino]sulfonyl]-benzamide. CAS Number: 313520-94-4. Molecular Formula: C21H20N2O3S....
| Schlagworte: | N-(phenylmethyl)-4-[[(phenylmethyl)amino]sulfonyl]-benzamide |
| Anwendung: | TH257 inactive kinase inhibitor analog, control |
| CAS | 313520-94-4 |
| MW: | 380.5 D |
ab 117,00 €
BMS-5
Artikelnummer: SYN-1024-M005
Soluble in DMSO. Kinases, such as LIM kinase 1 (LIMK1) and LIM kinase 2 (LIMK2), have been identified as participating in signal pathways affecting actin dynamics by deactivating cofilin. Over expression of LMK1 has been found in invasive breast and prostate cancer cell lines and suppression of LIMK 2 expression has...
| Schlagworte: | BMS5 |
| Anwendung: | LIMK1 / LIMK2 inhibitor |
| CAS | 1338247-35-0 |
| MW: | 431,3 D |
ab 106,00 €
Anti-LIMK1
Artikelnummer: A302-670A
Protein function: Serine/threonine-protein kinase that plays an essential role in the regulation of actin filament dynamics. Acts downstream of several Rho family GTPase signal transduction pathways. Activated by upstream kinases including ROCK1, PAK1 and PAK4, which phosphorylate LIMK1 on a threonine residue...
| Schlagworte: | Anti-LIMK, Anti-LIMK1, Anti-LIMK-1, EC=2.7.11.1, Anti-LIM domain kinase 1 |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Anti-LIMK1
Artikelnummer: A302-671A
Protein function: Serine/threonine-protein kinase that plays an essential role in the regulation of actin filament dynamics. Acts downstream of several Rho family GTPase signal transduction pathways. Activated by upstream kinases including ROCK1, PAK1 and PAK4, which phosphorylate LIMK1 on a threonine residue...
| Schlagworte: | Anti-LIMK, Anti-LIMK1, Anti-LIMK-1, EC=2.7.11.1, Anti-LIM domain kinase 1 |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Anti-LIM Kinase
Artikelnummer: 600-401-855
Protein function: Serine/threonine-protein kinase that plays an essential role in the regulation of actin filament dynamics. Acts downstream of several Rho family GTPase signal transduction pathways. Activated by upstream kinases including ROCK1, PAK1 and PAK4, which phosphorylate LIMK1 on a threonine residue...
| Schlagworte: | Anti-LIMK, Anti-LIMK1, Anti-LIMK-1, EC=2.7.11.1, Anti-LIM domain kinase 1 |
| Anwendung: | ELISA, IFM, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
684,00 €
Anti-LIM Kinase 1 / LIMK1
Artikelnummer: NSJ-R32135
0.5mg/ml if reconstituted with 0.2ml sterile DI water. LIM domain kinase 1 is an enzyme that in humans is encoded by the LIMK1 gene. There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc...
| Schlagworte: | Anti-LIMK, Anti-LIMK1, Anti-LIMK-1, EC=2.7.11.1, Anti-LIM domain kinase 1, LIM Kinase 1 Antibody / LIMK1 |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
755,00 €
BMS-3
Artikelnummer: AG-CR1-2901-M025
Off-white solid. Soluble in DMSO (5mg/ml). Potent LIMK (Lim kinase) inhibitor. Has IC50 values of 5nM and 6nM for LIMK1 and LIMK2, respectively.
| Schlagworte: | N-(5-(1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl)thiazol-2- yl)cyclopropanecarboxamide |
| Anwendung: | Potent LIMK inhibitor |
| CAS | 1338247-30-5 |
| MW: | 429,3 D |
ab 88,00 €
BMS-3
Artikelnummer: Cay19421-10
BMS-3 is a potent inhibitor of activated LIM domain kinases LIMK1 and LIMK2 (IC50s = 5 and 6 nM, respectively). It is used to study the role of activated LIMK isoforms in the signaling of Rho family GTPases to cytoskeletal proteins, including cofilin and tubulin.Formal Name:...
| Schlagworte: | N-[5-[1-(2,6-dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl]-2-thiazolyl]-cyclopropanecarboxamide |
| Anwendung: | LIMK1 / LIMK2 inhibitor |
| CAS | 1338247-30-5 |
| MW: | 429.3 D |
ab 43,00 €
Anti-LIMK1
Artikelnummer: E-AB-13381.120
There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM...
| Schlagworte: | Anti-LIMK, Anti-LIMK1, Anti-LIMK-1, EC=2.7.11.1, Anti-LIM domain kinase 1, LIMK1 Polyclonal Antibody |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 71,00 €
Anti-LIMK1, clone 175CT3.2.5
Artikelnummer: NSJ-F40237-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. Stimulates axonal outgrowth and may be involved in brain development. Isoform 3 has a...
| Schlagworte: | Anti-LIMK, Anti-LIMK1, Anti-LIMK-1, EC=2.7.11.1, Anti-LIM domain kinase 1, LIMK1 Antibody |
| Anwendung: | WB, ELISA |
| Wirt: | Mouse |
| Spezies-Reaktivität: | mouse |
ab 326,00 €
BMS-5
Artikelnummer: Cay21072-10
BMS-5 is a potent inhibitor of activated LIM domain kinases LIMK1 and LIMK2 with IC50 values of 7 and 8 nM, respectively. LIMK1 and LIMK2 participate in signal pathways affecting actin dynamics by deactivating cofilin. This compound can be used to study the role of activated LIMK isoforms in the signaling of Rho...
| Schlagworte: | LIM Kinase Inhibitor I, LIMKi 3,... |
| Anwendung: | LIMK1 / LIMK2 inhibitor |
| CAS | 1338247-35-0 |
| MW: | 431.3 D |
ab 65,00 €
Anti-phospho-LIMK1 (Thr508)
Artikelnummer: ABE-35-1122-50
Protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. Isoform 3 has a dominant negative effect on actin cytoskeletal changes. May be involved in brain development. Protein function:...
| Schlagworte: | Anti-phospho-LIMK, Anti-phospho-LIMK1, Anti-phospho-LIMK-1, Anti-phospho-LIM domain kinase 1, Polyclonal Antibody to LIMK1... |
| Anwendung: | WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
574,00 €