Zu "K05742" wurden 34 Artikel gefunden!
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EIPA
Artikelnummer: TGM-TQ0157-1mL
Description: EIPA (L593754) (L593754, MH 12-43) is a TRPP3 channel inhibitor (IC50: 10.5 µM). It also inhibits Na+/H+-exchanger (NHE) and macropinocytosis. Target: TRP/TRPV Channel, Sodium Channel. Smiles: CCN(C(C)C)c1nc(N)c(nc1Cl)C(=O)NC(N)=N. References: Dai XQ, et al. Inhibition of TRPP3 channel by MK-870 and...
| Schlagworte: | L593754, MH 12-43 |
| Anwendung: | NHE inhibitor |
| CAS | 1154-25-2 |
| MW: | 299.76 D |
ab 31,00 €
5-(N-ethyl-N-isopropyl)-Amiloride
Artikelnummer: Cay14406-5
Sodium-hydrogen exchangers (NHE) are involved in maintaining sodium and pH balance in a variety of tissues. They are also known as sodium-hydrogen antiporters and solute carrier family 9 members. 5-(N-ethyl-N-isopropyl)-Amiloride (EIPA) is a potent inhibitor of several NHE isoforms, inhibiting NHE1, NHE2, NHE3, and...
| Schlagworte: | EIPA, L-593,754, MH 12-43, 3-amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-2-pyrazinecarboxamide |
| Anwendung: | NHE inhibitor |
| CAS | 1154-25-2 |
| MW: | 299.8 D |
ab 78,00 €
BI-9627
Artikelnummer: TGM-T14566-10mg
Description: BI-9627 is a selective and potent sodium hydrogen exchange isomer 1 (NHE1) inhibitor.BI-9627 partially reverses the effects of DMA with IC50 values of 6 and 31 nM in the intracellular pH recovery (pHi) and human platelet lysis assays.BI-9627 is often used as a negative control for BI-0054, which can be...
| Anwendung: | NHE1 inhibitor |
| CAS | 1204329-34-9 |
| MW: | 356.34 D |
ab 52,00 €
KR-32568
Artikelnummer: TGM-T36569-100mg
Description: KR-32568 is a sodium/hydrogen exchanger 1 (NHE-1) inhibitor (IC50: 230 nM) with potent cardioprotective effects. At a concentration of 10 µM, it restored cardiac systolic function in an isolated ischemic rat heart model. Additionally, KR-32568 (0.3 mg/kg) reduced myocardial infarction size in a rat...
| Anwendung: | NHE-1 inhibitor |
| CAS | 852146-73-7 |
| MW: | 261.25 D |
ab 40,00 €
5-(N,N-dimethyl)-Amiloride (hydrochloride)
Artikelnummer: Cay19100-1
Sodium-hydrogen exchangers (NHE) are involved in maintaining sodium and pH balance in a variety of tissues. They are also known as sodium-hydrogen antiporters and solute carrier family 9 members. 5-(N,N-dimethyl)-Amiloride (DMA) inhibits NHE1, NHE2, and NHE3 with Ki values of 0.02, 0.25, and 14 µM, respectively....
| Schlagworte: | DMA, L-591,605, MK-685, 3-amino-N-(aminoiminomethyl)-6-chloro-5-(dimethylamino)-2-pyrazinecarboxamide, monohydrochloride |
| Anwendung: | Sodium-hydrogen exchangers (NHE) inhibitor |
| CAS | 2235-97-4 |
| MW: | 294.1 D |
ab 44,00 €
Cariporide
Artikelnummer: Cay16935-5
Cariporide is an inhibitor of sodium-hydrogen exchanger 1 (NHE-1, IC50 = 0.56 µM in an intracellular pH recovery assay). It is selective for NHE-1 over NHE-2 (IC50 = 28 µM in an intracellular pH recovery assay). Cariporide inhibits sodium propionate-induced swelling of isolated human platelets (IC50 = 0.023 µM). It...
| Schlagworte: | HOE 642, N-(aminoiminomethyl)-4-(1-methylethyl)-3-(methylsulfonyl)-benzamide |
| Anwendung: | NHE-1 inhibitor |
| CAS | 159138-80-4 |
| MW: | 283.3 D |
ab 85,00 €
Anti-NHE1
Artikelnummer: NSJ-R31571
0.5mg/ml if reconstituted with 0.2ml sterile DI water. NHE1, also known as SLC9A1, is an isoform of sodium-hydrogen antiporter that in humans is encoded by the SLC9A1 gene. It is mapped to 1p36.11. NHE1 is a ubiquitous membrane-bound enzyme involved in pH regulation of vertebrate cells. It is specifically inhibited...
| Schlagworte: | Anti-APNH, Anti-NHE-1, Anti-APNH1, Anti-SLC9A1, Anti-Na(+)/H(+) exchanger 1, Anti-Sodium/hydrogen exchanger 1, Anti-Solute... |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
772,00 €
Zoniporide (hydrochloride)
Artikelnummer: Cay16004-1
The sodium-hydrogen exchanger isoform-1 (NHE-1) is the most predominant isoform of the Na+/H+ exchanger and is expressed in the heart where it contributes to cardiomyocyte pH homeostasis. It plays an important role in the myocardial response to ischemia-reperfusion. Zoniporide inhibits human NHE-1 with an IC50 value...
| Schlagworte: | CP 597,396, N-(aminoiminomethyl)-5-cyclopropyl-1-(5-quinolinyl)-1H-pyrazole-4-carboxamide, monohydrochloride |
| Anwendung: | Na+-H+ exchange subtype 1 (NHE-1) inhibitor |
| CAS | 241800-97-5 |
| MW: | 356.8 D |
ab 52,00 €
KR-32568
Artikelnummer: Cay23968-5
KR-32568 is an inhibitor of the sodium-hydrogen exchanger isoform-1 (NHE-1, IC50 = 230 nM). It restores cardiac contractile function ex vivo in an isolated ischemic rat heart model when used at a concentration of 10 µM. KR-32568 (0.3 mg/kg) reduces myocardial infarct size in a rat model of ischemia and reperfusion...
| Schlagworte: | N-(aminoiminomethyl)-5-(5-fluoro-2-methylphenyl)-2-furancarboxamide |
| Anwendung: | NHE-1 inhibitor |
| CAS | 852146-73-7 |
| MW: | 261.3 D |
ab 94,00 €
BI-9627
Artikelnummer: Cay27640-5
BI-9627 is an inhibitor of sodium-hydrogen exchanger isoform 1 (NHE1), with IC50 values of 6 and 31 nM in intracellular pH recovery (pHi) and human platelet swelling assays, respectively. It is greater than 30-fold selective for NHE1 over NHE2 and is inactive at NHE3 up to 16 µM in a pHi assay. BI-9627 inhibits...
| Schlagworte: | 4-(1-acetyl-4-piperidinyl)-N-(aminoiminomethyl)-3-(trifluoromethyl)-benzamide |
| Anwendung: | NHE1 inhibitor |
| CAS | 1204329-34-9 |
| MW: | 356.3 D |
ab 52,00 €
Anti-Nhe-1
Artikelnummer: 600-401-DA7
Anti-Nhe-1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Nhe-1 from other sources has not been determined. Protein function: Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions....
| Schlagworte: | Anti-APNH, Anti-APNH1, Anti-NHE-1, Anti-SLC9A1, Anti-Na(+)/H(+) exchanger 1, Anti-Sodium/hydrogen exchanger 1, Anti-Solute... |
| Anwendung: | ELISA, IHC, IFM, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
834,00 €
Anti-Nhe-1
Artikelnummer: 600-401-DA8
Anti-Nhe-1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Nhe-1 from other sources has not been determined. Protein function: Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions....
| Schlagworte: | Anti-APNH, Anti-APNH1, Anti-NHE-1, Anti-SLC9A1, Anti-Na(+)/H(+) exchanger 1, Anti-Sodium/hydrogen exchanger 1, Anti-Solute... |
| Anwendung: | ELISA, IHC, IFM, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
834,00 €