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Zu "K05734" wurden 38 Artikel gefunden!
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Artikelnummer: BPS-82181
The Chemi-Verse(TM) PAK4 Kinase Assay Kit is designed to measure PAK4 (p21-activated kinase 4) serine/threonine kinase activity for screening and profiling applications using ADP-Glo(TM) as a detection reagent. The assay kit comes in a convenient 96-well format, with enough purified recombinant PAK4 kinase, kinase...
Schlagworte: | PAK4, PAK-4, KIAA1142, EC=2.7.11.1, p21-activated kinase 4, Serine/threonine-protein kinase PAK 4, |
Anwendung: | Enzyme kinetics, screen small molecule inhibitor screening, drug discovery, HTS |
Spezies-Reaktivität: | human |
789,00 €
Artikelnummer: ELK-ELK4309.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PAK4. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PAK4. Next,...
Schlagworte: | PAK4, PAK-4, KIAA1142, EC=2.7.11.1, p21-activated kinase 4, Serine/threonine-protein kinase PAK 4 |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: Cay19186-5
p21-Activated kinases (PAKs) are STE20 serine/threonine kinases that are vital to normal cell function. Binding of various upstream partners to PAKs results in release of an autoinhibitory domain that blocks activity of the kinase domain. PAKs are upregulated in several human cancers and are potential therapeutic...
Schlagworte: | PF-309,... |
Anwendung: | ATP-competitive PAK4 inhibitor |
CAS | 898044-15-0 |
MW: | 490.6 D |
ab 84,00 €
Artikelnummer: A300-356A
Protein function: Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, growth, proliferation or cell survival. Activation by various effectors including growth factor receptors or active CDC42 and RAC1 results in a...
Schlagworte: | Anti-PAK4, Anti-PAK-4, Anti-KIAA1142, EC=2.7.11.1, Anti-p21-activated kinase 4, Anti-Serine/threonine-protein kinase PAK 4 |
Anwendung: | WB, IP |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 164,00 €
Artikelnummer: 600-401-DJ3
Anti-PAK4 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with PAK4 from other sources has not been determined. Protein function: Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton...
Schlagworte: | Anti-PAK4, Anti-PAK-4, Anti-KIAA1142, EC=2.7.11.1, Anti-p21-activated kinase 4, Anti-Serine/threonine-protein kinase PAK 4 |
Anwendung: | ELISA, IHC, IFM, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
684,00 €
Artikelnummer: 0252-100
Schlagworte: | Serine/threonine-protein kinase PAK 4, EC=2.7.11.1 |
Anwendung: | WB |
Wirt: | Mouse |
Spezies-Reaktivität: | human, mouse, rat, dog |
383,00 €
Artikelnummer: NSJ-F43855-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Pak4 activates the JNK pathway. Plays a role in the reorganization of the actin cytoskeleton and in the formation of filopodia. Phosphorylates and inactivates the protein phosphatase SSH1, leading to increased inhibitory phosphorylation of the actin binding/depolymerizing...
Schlagworte: | Anti-Pak4, Anti-PAK-4, Anti-Kiaa1142, EC=2.7.11.1, Anti-p21-activated kinase 4, Anti-Serine/threonine-protein kinase PAK... |
Anwendung: | WB, FC, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 326,00 €
Artikelnummer: LKT-P2000.1
PAK4 inhibitor.
Schlagworte: | PF-3758309 |
Anwendung: | PAK4 inhibitor |
CAS | 1279034-84-2 |
MW: | 563.55 D |
ab 139,00 €
Artikelnummer: NSJ-F50893-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3, PAK4, PAK5, and PAK6. PAK proteins serve as targets for the small...
Schlagworte: | Anti-PAK4, Anti-PAK-4, Anti-KIAA1142, EC=2.7.11.1, Anti-p21-activated kinase 4, Anti-Serine/threonine-protein kinase PAK... |
Anwendung: | IHC, WB, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 326,00 €
Artikelnummer: NSJ-RQ4826
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. PAK proteins, a family of serine/threonine p21-activating kinases, serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities. Protein function: Serine/threonine...
Schlagworte: | Anti-PAK4, Anti-PAK-4, Anti-KIAA1142, EC=2.7.11.1, Anti-p21-activated kinase 4, Anti-Serine/threonine-protein kinase PAK... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
755,00 €
Artikelnummer: Cay29458-5
GNE-2861 is an inhibitor of the group 2 p21-activated kinases (PAKs, IC50s = 7.5, 126, and 36 nM for PAK4, -5, and -6, respectively). It is selective for group 2 PAKs over group 1 PAKs (IC50s = 5.42, 0.97, and >10 µM for PAK1, -2, and -3, respectively), as well as JAK3, KHS1, MAP4K4, and MINK1 at 1 µM. GNE-2861...
Schlagworte: | 1-[2-[1-(2-amino-4-pyrimidinyl)-2-[(2-methoxyethyl)amino]-1H-benzimidazol-6-yl]ethynyl]-cyclohexanol |
Anwendung: | Group 2 p21-activated kinase (PAK4, PAK5, PAK6) inhibitor |
CAS | 1394121-05-1 |
MW: | 406.5 D |
406,00 €
Artikelnummer: ARG43159.50
Protein function: Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, growth, proliferation or cell survival. Activation by various effectors including growth factor receptors or active CDC42 and RAC1 results in a...
Schlagworte: | Anti-PAK4, Anti-PAK-4, Anti-PAK-4, Anti-KIAA1142, Anti-p21-activated kinase 4, Anti-p21-activated kinase 4,... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
520,00 €