Zu "K05733" wurden 52 Artikel gefunden!
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Anti-Recombinant PAK3, clone A320
Artikelnummer: E-AN301617L.100
The p21-activated kinase (PAK) family of serine/threonine kinases is engaged in multiple cellular processes, including cytoskeletal reorganization, MAPK signaling, apoptotic signaling, control of phagocyte NADPH oxidase, and Plays a role in dendrite spine morphogenesis as well as synapse formation.
| Schlagworte: | Anti-PAK3, Anti-Beta-PAK, Anti-Oligophrenin-3, Anti-p21-activated kinase 3, Anti-Serine/threonine-protein kinase PAK 3,... |
| Anwendung: | WB, IHC, IF, FCM |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat, mouse |
ab 304,00 €
FRAX486
Artikelnummer: Cay24682-5
FRAX486 is an inhibitor of group I p21-activated kinases (PAKs, IC50s = 8.25, 39.5, and 55.3 nM for PAK1, PAK2, and PAK3, respectively). It is selective for group I PAKs over PAK4, a group II PAK (IC50 = 779 nM). FRAX486 (20 mg/kg) reverses decreases in the mean density of apical dendritic spines in the temporal...
| Schlagworte: | 6-(2,4-dichlorophenyl)-8-ethyl-2-[[3-fluoro-4-(1-piperazinyl)phenyl]amino]-pyrido[2,3-d]pyrimidin-7(8H)-one |
| Anwendung: | PAK1 / PAK2 / PAK3 inhibitor |
| CAS | 1232030-35-1 |
| MW: | 513.4 D |
ab 54,00 €
Anti-phospho-PAK1 / PAK2 / PAK3 (Thr423/Thr402/Thr421)
Artikelnummer: ARG51663.100
Protein function: Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, or cell cycle regulation. Plays a role in dendrite spine morphogenesis as well as synapse formation and plasticity. Acts as downstream effector of the...
| Schlagworte: | Anti-phospho-PAK3, Anti-phospho-OPHN3, Anti-phospho-PAK-3, Anti-phospho-Beta-PAK, EC=2.7.11.1,... |
| Anwendung: | ICC, IF, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 471,00 €
Anti-PAK3
Artikelnummer: NSJ-R31839
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Serine/threonine-protein kinase PAK 3 is an enzyme that in humans is encoded by the PAK3 gene. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine...
| Schlagworte: | Anti-PAK3, Anti-PAK-3, Anti-OPHN3, Anti-Beta-PAK, EC=2.7.11.1, Anti-Oligophrenin-3, Anti-p21-activated kinase 3,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-PAK3
Artikelnummer: NSJ-F43370-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Key regulator of synapse formation and plasticity in the hippocampus. Protein function: Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, or cell cycle regulation. Plays a role...
| Schlagworte: | Anti-Pak3, Anti-PAK-3, Anti-Pak-3, Anti-Beta-PAK, EC=2.7.11.1, Anti-p21-activated kinase 3, Anti-CDC42/RAC effector kinase... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 361,00 €
Anti-PAK3
Artikelnummer: NSJ-F50892-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. PAK3, a member of the STE20 subfamily of Ser/Thr protein kinases, acts on a variety of targets. PAK3 interacts tightly with GTP-bound but not GDP-bound CDC42/p21 and RAC1. It shows highly specific binding to the SH3 domains of phospholipase C-gamma and of adapter protein...
| Schlagworte: | Anti-PAK3, Anti-OPHN3, Anti-PAK-3, Anti-Beta-PAK, EC=2.7.11.1, Anti-Oligophrenin-3, Anti-p21-activated kinase 3,... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
FRAX597
Artikelnummer: Cay22205-25
FRAX597 is an inhibitor of p21-activated kinase (PAK) that is selective for group I PAKs (IC50s = 7.7, 12.8, and 19.3 nM for PAK 1, 2, and 3, respectively) over group II PAKs (IC50 > 10 µM for PAK4 and 50 = 70 nM), prevents proliferation of transformed Schwann cells by halting the cell cycle in the G1 phase, and...
| Schlagworte: | 6-[2-chloro-4-(5-thiazolyl)phenyl]-8-ethyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-pyrido[2,3-d]pyrimidin-7(8H)-one |
| Anwendung: | p21-activated kinase inhibitor |
| CAS | 1286739-19-2 |
| MW: | 558.1 D |
ab 57,00 €
Anti-PAK3, clone ADFC-16
Artikelnummer: NSJ-RQ4788
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of...
| Schlagworte: | Anti-PAK3, Anti-PAK-3, Anti-OPHN3, Anti-Beta-PAK, EC=2.7.11.1, Anti-Oligophrenin-3, Anti-p21-activated kinase 3,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-PAK1/2/3 (pS144/pS141/pS139), clone CFF-16
Artikelnummer: NSJ-RQ4789
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. PAK proteins, a family of serine/threonine p21-activating kinases, serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities. Protein function: Serine/threonine...
| Schlagworte: | Anti-PAK3, Anti-PAK-3, Anti-OPHN3, Anti-Beta-PAK, EC=2.7.11.1, Anti-Oligophrenin-3, Anti-p21-activated kinase 3,... |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
790,00 €
Anti-PAK3
Artikelnummer: ATA-HPA060219.100
Protein function: Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, or cell cycle regulation. Plays a role in dendrite spine morphogenesis as well as synapse formation and plasticity. Acts as downstream effector of the...
| Schlagworte: | Anti-PAK3, Anti-PAK-3, Anti-OPHN3, Anti-Beta-PAK, EC=2.7.11.1, Anti-Oligophrenin-3, Anti-p21-activated kinase 3,... |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
Anti-PAK3
Artikelnummer: CSB-PA103384.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: PAK3. Antigen Species: Human
| Schlagworte: | Anti-PAK3, Anti-PAK-3, Anti-OPHN3, Anti-Beta-PAK, EC=2.7.11.1, Anti-Oligophrenin-3, Anti-p21-activated kinase 3,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
Anti-PAK3
Artikelnummer: CSB-PA438958.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: PAK3. Antigen Species: Human
| Schlagworte: | Anti-PAK3, Anti-PAK-3, Anti-OPHN3, Anti-Beta-PAK, EC=2.7.11.1, Anti-Oligophrenin-3, Anti-p21-activated kinase 3,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €