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BIRT 377
BIRT 377

Artikelnummer: Cay43171-10

BIRT 377 is a negative allosteric modulator (NAM) of lymphocyte function-associated antigen-1 (LFA-1). It binds to LFA-1 at a site distal to residues involved in intercellular adhesion molecule interactions and induces a conformational change to its inactive state. BIRT 377 selectively inhibits the interaction of...
Schlagworte: (5R)-5-[(4-bromophenyl)methyl]-3-(3,5-dichlorophenyl)-1,5-dimethyl-2,4-imidazolidinedione
Anwendung: Negative allosteric lymphocyte function-associated antigen-1 (LFA-1) modulator
CAS 213211-10-0
MW: 442.13 D
ab 231,00 €
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Anti-CD11a (bovine), clone HUH73A
Anti-CD11a (bovine), clone HUH73A

Artikelnummer: WS0586B-100

The monoclonal antibody was produced in ascites fluid, clarified by filtration through a 0.2 micrometer filter.
Schlagworte: Anti-CD11a, Anti-ITGAL, Anti-LFA-1A, Anti-Integrin alpha-L, Anti-CD11 antigen-like family member A, Anti-Leukocyte...
Anwendung: FC, IHC, Cell Function
Wirt: Mouse
Spezies-Reaktivität: bison, bovine, caprine, dog, human, ovine
343,00 €
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Anti-LFA-1
Anti-LFA-1

Artikelnummer: NSJ-R36394-100UG

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Lymphocyte function-associated antigen 1, CD11A, integrin alpha L (ITGAL) Protein function: Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety...
Schlagworte: Anti-CD11A, Anti-ITGAL, Anti-CD11a, Anti-LFA-1A, Anti-Integrin alpha-L, Anti-CD11 antigen-like family member A,...
Anwendung: WB, IHC, ELISA (peptide)
Wirt: Goat
Spezies-Reaktivität: human
836,00 €
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Lifitegrast
Lifitegrast

Artikelnummer: Cay22588-10

Lifitegrast is an inhibitor of the protein-protein interaction between lymphocyte function-associated antigen-1 (LFA-1) and intercellular adhesion molecule-1 (ICAM-1). It binds to LFA-1 and blocks the adhesion of Jurkat T cells or HuT 78 cells to ICAM-1 (IC50s = 2.98 and 9 nM, respectively) and inhibits the...
Schlagworte: SAR 1118,...
Anwendung: CD11A blocker
CAS 1025967-78-5
MW: 615.5 D
ab 49,00 €
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Anti-CD11a / LFA-1
Anti-CD11a / LFA-1

Artikelnummer: NSJ-R32698

0.5mg/ml if reconstituted with 0.2ml sterile DI water. CD11a, also known as ITGAL or LFA-1, is a human gene which functions in the immune system. It is mapped to 16p11.2. CD11a is involved in cellular adhesion and costimulatory signaling. It is the target of the drug efalizumab. CD11a encodes the integrin alpha L...
Schlagworte: Anti-ITGAL, Anti-CD11a, Anti-CD11A, Anti-LFA-1A, Anti-Integrin alpha-L, Anti-CD11 antigen-like family member A,...
Anwendung: WB, FC, ICC
Wirt: Rabbit
Spezies-Reaktivität: human
790,00 €
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Anti-CD11a / LFA-1 alpha, clone I21/7
Anti-CD11a / LFA-1 alpha, clone I21/7

Artikelnummer: ARG20829.100

Schlagworte: Anti-Integrin alpha-L
Anwendung: FC, IHC (frozen), ICC, IF, IP, BL
Wirt: Rat
Spezies-Reaktivität: mouse
586,00 €
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Anti-CD11a / LFA-1 alpha (FITC), clone I21/7
Anti-CD11a / LFA-1 alpha (FITC), clone I21/7

Artikelnummer: ARG20830.100

Schlagworte: Anti-Integrin alpha-L
Anwendung: FC, IHC (frozen), ICC, IF, BL
Wirt: Rat
Spezies-Reaktivität: mouse
625,00 €
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Anti-CD11a / LFA-1 alpha (PE-Cy7), clone I21/7
Anti-CD11a / LFA-1 alpha (PE-Cy7), clone I21/7

Artikelnummer: ARG20834.50

Schlagworte: Anti-Integrin alpha-L
Anwendung: FC, IHC (frozen), ICC, IF, BL
Wirt: Rat
Spezies-Reaktivität: mouse
518,00 €
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Anti-CD11a / LFA-1 alpha (Biotin), clone 38
Anti-CD11a / LFA-1 alpha (Biotin), clone 38

Artikelnummer: ARG21252.50

Protein function: Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. [The UniProt Consortium]
Schlagworte: Anti-CD11a, Anti-CD11A, Anti-ITGAL, Anti-LFA-1A, Anti-Integrin alpha-L, Anti-CD11 antigen-like family member A,...
Anwendung: FC, IHC (frozen), FA (blocking), ELISA
Wirt: Mouse
Spezies-Reaktivität: human
427,00 €
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Anti-CD11a / LFA-1 alpha (PE), clone 38
Anti-CD11a / LFA-1 alpha (PE), clone 38

Artikelnummer: ARG21253.50

Protein function: Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. [The UniProt Consortium]
Schlagworte: Anti-CD11a, Anti-CD11A, Anti-ITGAL, Anti-LFA-1A, Anti-Integrin alpha-L, Anti-CD11 antigen-like family member A,...
Anwendung: FC, IHC (frozen), FA (blocking), ELISA
Wirt: Mouse
Spezies-Reaktivität: human
493,00 €
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Anti-CD11a, clone MEM-25 (APC)
Anti-CD11a, clone MEM-25 (APC)

Artikelnummer: ARG53758.100

Protein function: Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. [The UniProt Consortium]
Schlagworte: Anti-ITGAL, Anti-CD11A, Anti-CD11a, Anti-LFA-1A, Anti-Integrin alpha-L, Anti-CD11 antigen-like family member A,...
Anwendung: FC, IP, FA
Wirt: Mouse
Spezies-Reaktivität: human
734,00 €
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Anti-CD11a, clone MEM-25 (PE)
Anti-CD11a, clone MEM-25 (PE)

Artikelnummer: ARG53759.100

Protein function: Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. [The UniProt Consortium]
Schlagworte: Anti-ITGAL, Anti-CD11A, Anti-CD11a, Anti-LFA-1A, Anti-Integrin alpha-L, Anti-CD11 antigen-like family member A,...
Anwendung: FC
Wirt: Mouse
Spezies-Reaktivität: human
734,00 €
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