Zu "K05697" wurden 111 Artikel gefunden!
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Sodium Stibogluconate
Artikelnummer: Cay16038-250
Sodium stibogluconate is a pentavalent antimony derivative that is highly active against Leishmania amastigotes in macrophages. Sodium stibogluconate has diverse effects on both this intracellular parasite and its host cell.Formal Name: 2,4:2',4'-O-(oxydistibylidyne)bis-D-gluconic acid, trisodium salt, nonahydrate....
| Schlagworte: | Antimony Sodium Gluconate, 2,4:2',4'-O-(oxydistibylidyne)bis-D-gluconic acid, trisodium salt, nonahydrate |
| Anwendung: | Antiprotozoal, leishmanicidal, pentavalent antimonial, protein tyrosine phosphatase inhibitor |
| CAS | 16037-91-5 |
| MW: | 907.9 D |
ab 73,00 €
TPI-1
Artikelnummer: Cay22480-1
TPI-1 is an inhibitor of protein tyrosine phosphatases. TPI-1 (10 ng/ml) increases phosphorylated substrates of the phosphatase SHP-1 in Jurkat T cells, including pLck-pY394, pZap70, and pSlp76. It is selective for SHP-1 over SHP-2, having low activity at the SHP-2 substrate pERK1/2. It increases pLck-pY394 levels...
| Schlagworte: | Tyrosine Phosphatase Inhibitor 1, 2-(2,5-dichlorophenyl)-2,5-cyclohexadiene-1,4-dione |
| Anwendung: | SHP1 inhibitor |
| CAS | 79756-69-7 |
| MW: | 253.1 D |
ab 56,00 €
NSC 87877
Artikelnummer: Cay14908-50
The Src homology region 2 domain-containing phosphatases (SHP) known as SHP-1 and SHP-2 act downstream of receptor and non-receptor tyrosine kinase to modulate signal transduction. NSC 87877 is a cell-permeable, inhibitor of both SHP-1 and SHP-2 (IC50 = 355 and 318 nM, respectively). It is much less effective...
| Schlagworte: | 8-hydroxy-7-[2-(6-sulfo-2-naphthalenyl)diazenyl]-5-quinolinesulfonic acid |
| Anwendung: | SHP-1 / SHP-2 inhibitor |
| CAS | 56990-57-9 |
| MW: | 459.4 D |
ab 57,00 €
Anti-SHP1, clone PTY11
Artikelnummer: ARG10057.100
Protein function: Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon...
| Schlagworte: | Anti-HCP, Anti-PTPN6, Anti-PTP-1C, Anti-SH-PTP1, EC=3.1.3.48, Anti-Protein-tyrosine phosphatase 1C, Anti-Protein-tyrosine... |
| Anwendung: | ELISA, ICC, IF, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
658,00 €
Anti-phospho-SHP-1 (Tyr536)
Artikelnummer: ARG51791.100
Protein function: Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon...
| Schlagworte: | Anti-phospho-HCP, Anti-phospho-PTPN6, Anti-phospho-PTP-1C, Anti-phospho-SH-PTP1, EC=3.1.3.48,... |
| Anwendung: | ICC, IF, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 471,00 €
Anti-PTPN6 / SHP1
Artikelnummer: ARG57507.100
Protein function: Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon...
| Schlagworte: | Anti-HCP, Anti-PTPN6, Anti-PTP-1C, Anti-SH-PTP1, EC=3.1.3.48, Anti-Protein-tyrosine phosphatase 1C, Anti-Protein-tyrosine... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
707,00 €
Anti-PTPN6 / SHP1, Internal
Artikelnummer: ARG64175.100
Protein function: Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon...
| Schlagworte: | Anti-HCP, Anti-PTPN6, Anti-PTP-1C, Anti-SH-PTP1, EC=3.1.3.48, Anti-Protein-tyrosine phosphatase 1C, Anti-Protein-tyrosine... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, mouse, rat |
871,00 €
Anti-PTPN6 / SHP1, Internal
Artikelnummer: ARG64215.100
Protein function: Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon...
| Schlagworte: | Anti-HCP, Anti-PTPN6, Anti-PTP-1C, Anti-SH-PTP1, EC=3.1.3.48, Anti-Protein-tyrosine phosphatase 1C, Anti-Protein-tyrosine... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
871,00 €
Anti-PTPN6/SHP1
Artikelnummer: A304-969A
Protein function: Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon...
| Schlagworte: | Anti-HCP, Anti-PTPN6, Anti-PTP-1C, Anti-SH-PTP1, EC=3.1.3.48, Anti-Protein-tyrosine phosphatase 1C, Anti-Protein-tyrosine... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-SHP-1
Artikelnummer: NSJ-R34303-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Protein tyrosine phosphatase, non-receptor type 6, HCP, Hematopoietic cell phosphatase, PTPN6 Protein function: Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT...
| Schlagworte: | Anti-HCP, Anti-PTPN6, Anti-PTP-1C, Anti-SH-PTP1, EC=3.1.3.48, Anti-Protein-tyrosine phosphatase 1C, Anti-Protein-tyrosine... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €
Anti-SHP-1
Artikelnummer: NSJ-R34361-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Hematopoietic cell phosphatase, HCP, PTPN6 Protein function: Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may...
| Schlagworte: | Anti-HCP, Anti-PTPN6, Anti-PTP-1C, Anti-SH-PTP1, EC=3.1.3.48, Anti-Protein-tyrosine phosphatase 1C, Anti-Protein-tyrosine... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, mouse, rat |
836,00 €
Anti-PTPN6
Artikelnummer: E-AB-10587.120
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem...
| Schlagworte: | Anti-HCP, Anti-PTPN6, Anti-PTP-1C, Anti-SH-PTP1, EC=3.1.3.48, Anti-Protein-tyrosine phosphatase 1C, Anti-Protein-tyrosine... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €