Zu "K05697" wurden 91 Artikel gefunden!
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Anti-PTPN6
Artikelnummer: ABS-KC-2611.100
Protein function: Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon...
| Schlagworte: | Anti-Tyrosine-protein phosphatase non-receptor type 6, Anti-Hematopoietic cell protein-tyrosine phosphatase,... |
| Anwendung: | IP |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 206,00 €
Anti-PTPN6
Artikelnummer: ABS-KC-2659.100
Protein function: Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon...
| Schlagworte: | Anti-Tyrosine-protein phosphatase non-receptor type 6, Anti-Hematopoietic cell protein-tyrosine phosphatase,... |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 206,00 €
Anti-PTPN6
Artikelnummer: ABS-OC-325.100
Protein function: Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon...
| Schlagworte: | Anti-Tyrosine-protein phosphatase non-receptor type 6, Anti-Hematopoietic cell protein-tyrosine phosphatase,... |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 206,00 €
Anti-PTPN6
Artikelnummer: ABS-KC-6191.100
Protein function: Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon...
| Schlagworte: | Anti-Tyrosine-protein phosphatase non-receptor type 6, Anti-Hematopoietic cell protein-tyrosine phosphatase,... |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 232,00 €
2-Bromo-4'-hydroxyacetophenone
Artikelnummer: TGM-T7084-500mg
Description: 2-Bromo-4'-hydroxyacetophenone(PTP Inhibitor I) is a cell-permeable, protein tyrosine phosphatase (PTP) inhibitor that covalently blocks the catalytic domain of the Src homology region 2 domain-containing phosphatase (SHP-1(DeltaSH2)) with a Ki value of 43 µM and PTP1B with a Ki value of 42 µM [1]....
| Schlagworte: | SHP-1 Inhibitor II, PTP Inhibitor I, alpha-Bromo-4-hydroxyacetophenone, 4-Hydroxyphenacyl bromide |
| Anwendung: | Cell-permeable, protein tyrosine phosphatase inhibitor, SHP-1/PTP1B inhibitor |
| CAS | 2491-38-5 |
| MW: | 215.04 D |
34,00 €
SC-43
Artikelnummer: TGM-T8478-100mg
Description: SC-43 is a potent and orally active agonist of SHP-1 (PTPN6). SC-43 inhibits the phosphorylation of STAT3 and induces cell apoptosis, and with anti-fibrotic and anticancer effects. Target: STAT, Apoptosis, Phosphatase. Smiles: FC(F)(F)c1cc(NC(=O)Nc2cccc(Oc3ccc(cc3)C#N)c2)ccc1Cl. References: Ming-Hung...
| Anwendung: | SHP-1 activator |
| CAS | 1400989-25-4 |
| MW: | 431.8 D |
ab 97,00 €
PTP1C Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPJ-00465-10ug
Description: Protein-Tyrosine Phosphatase 1C (PTP1C) belongs to the protein-tyrosine phosphatase family.which is known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTP1C is highly expressed in leukocyte...
| Schlagworte: | SH-PTP1, Hematopoietic Cell Protein-Tyrosine Phosphatase, HCP, Protein-Tyrosine Phosphatase SHP-1, Protein-Tyrosine... |
| MW: | 34 kD |
ab 181,00 €
SHP-1 Protein, Mouse, Recombinant (aa 207-597, His & GST)
Artikelnummer: TGM-TMPY-03296-100ug
Description: PTPN6 is an enzyme that belongs to the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of PTPN6 contains two tandem Src homolog (SH2)...
| Schlagworte: | SH-PTP1, Hcph, 70Z-SHP, Ptp1C, protein tyrosine phosphatase, non-receptor type 6, me, hcp, PTPTY-42, SHP-1 |
| MW: | 72.7 kD |
699,00 €
3alpha-Aminocholestane
Artikelnummer: TGM-T14037-1mg
Description: 3alpha-Aminocholestane (5alpha-Cholestan-3alpha-amine) is a potent inhibitor of inositol-5'-phosphatase 1 (SHIP1) containing the SH2 structural domain (IC50 : 2.5 µM) for research and immune-related diseases. Target: Phosphatase. Smiles:...
| Schlagworte: | 5alpha-Cholestan-3alpha-amine |
| Anwendung: | SHP-1 inhibitor |
| CAS | 2206-20-4 |
| MW: | 387.68 D |
49,00 €
Sodium stibogluconate
Artikelnummer: TGM-T13013-100mg
Description: Sodium stibogluconate (Stibogluconate trisodium nonahydrate) is a potent inhibitor of protein tyrosine phosphatase. Target: Phosphatase. Smiles: O=[Sb](O[C@]1([H])[C@H](O)CO)(O[C@@H](C(O)=O)[C@H]1O)O[Sb](O[C@]2([H])[C@H](O)CO)(O[C@@H](C(O)=O)[C@H]2O)=O.O.O.O.O.O.O.O.O.O.[Na+].[Na+].[Na+]. References:...
| Schlagworte: | Stibogluconate trisodium nonahydrate |
| Anwendung: | Targets tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48] (PTPN6, SHP1) |
| CAS | 16037-91-5 |
| MW: | 907.88 D |
49,00 €
TPI-1
Artikelnummer: TGM-T3962-100mg
Description: TPI-1 is a SHP-1 inhibitor. Target: Glucocorticoid Receptor, Phosphatase. Smiles: Clc1ccc(Cl)c(c1)C1=CC(=O)C=CC1=O. References: Kundu S, et al. Novel SHP-1 inhibitors tyrosine phosphatase inhibitor-1 and analogs with preclinical anti-tumor activities as tolerated oral agents. J Immunol. 2010 Jun...
| Schlagworte: | TPI 1, TPI1 |
| Anwendung: | SHP1 inhibitor |
| CAS | 79756-69-7 |
| MW: | 253.08 D |
ab 48,00 €
Anti-PTPN6
Artikelnummer: CSB-PA004085.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-HCP, Anti-PTPN6, Anti-PTP-1C, Anti-SH-PTP1, EC=3.1.3.48, Anti-Protein-tyrosine phosphatase 1C, Anti-Protein-tyrosine... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 126,00 €