Zu "K05696" wurden 72 Artikel gefunden!
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CX-08005
Artikelnummer: Cay42730-1
CX-08005 is an inhibitor of protein tyrosine phosphatase 1B (PTP1B, IC50 = 0. µM). It is selective for PTP1B over Src homology region 2 domain-containing phosphatase 1 (SHP-1), dual-specificity phosphatase 3 (DUSP3), and leukocyte common antigen-related (LAR) phosphatase at 10 µM but does inhibit T cell protein...
| Schlagworte: | 2-[[[2-(tetradecyloxy)phenyl]amino]carbonyl]-benzoic acid |
| Anwendung: | PTP1B inhibitor |
| CAS | 1256341-22-6 |
| MW: | 453.62 D |
ab 39,00 €
Anti-PTPN1
Artikelnummer: ABS-KC-3217.100
Protein function: Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK, inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c- src-induced signal transduction cascades....
| Schlagworte: | Anti-Tyrosine-protein phosphatase non-receptor type 1, Anti-Protein-tyrosine phosphatase 1B, Anti-PTP-1B, PTPN1 Antibody |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 206,00 €
Anti-PTPN1
Artikelnummer: ABS-OC-552.100
Protein function: Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK, inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c- src-induced signal transduction cascades....
| Schlagworte: | Anti-Tyrosine-protein phosphatase non-receptor type 1, Anti-Protein-tyrosine phosphatase 1B, Anti-PTP-1B, PTPN1 Antibody |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 206,00 €
TCS 401
Artikelnummer: TGM-T7381-100mg
Description: TCS 401 is a selective inhibitor of protein-tyrosine phosphatase 1B (PTP1B) with a Ki value of 0.29 µM. Target: Phosphatase. Smiles: Cl.OC(=O)C(=O)Nc1sc2CNCCc2c1C(O)=O. References: Du Z D , Hu L T , Zhao G Q , et al. Protein tyrosine phosphatase 1B regulates the activity of retinal pigment epithelial...
| Anwendung: | Selective PTP1B inhibitor |
| CAS | 243966-09-8 |
| MW: | 306.72 D |
ab 45,00 €
PTP1B Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPY-04125-100ug
Description: PTP1B, also known as PTPN1, belongs to the protein-tyrosine phosphatase (PTP) family. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are...
| Schlagworte: | PTPN1, PTP1B, protein tyrosine phosphatase, non-receptor type 1 |
| MW: | 38.1 kD |
ab 450,00 €
MSI-1436
Artikelnummer: TGM-T12116-100mg
Description: MSI-1436 is a selective, non-competitive inhibitor of the enzyme protein-tyrosine phosphatase 1B (PTB1B) with an IC50 of approximately 1 µM. Target: Others. Smiles: O[C@H]1[C@@]2([C@@]([C@]3(C)[C@@](C1)(C[C@@H](NCCCNCCCCN...
| Schlagworte: | Trodusquemine, Aminosterol-1436 |
| Anwendung: | Targets tyrosine-protein phosphatase non-receptor type 1 [EC:3.1.3.48] (PTPN1, PTP1B) |
| CAS | 186139-09-3 |
| MW: | 685.06 D |
ab 19.831,00 €
Cyclopenol
Artikelnummer: TGM-T125421-1mg
Target: Others. Smiles: CN1C(=O)c2ccccc2NC(=O)[C@]11O[C@@H]1c1cccc(O)c1
| Anwendung: | Fungal metabolite, PTP1B inhibitor |
| CAS | 20007-85-6 |
| MW: | 310.309 D |
ab 457,00 €
Ertiprotafib
Artikelnummer: TGM-T15243-25mg
Description: Ertiprotafib (PTP 112), a selective and potent inhibitor of protein tyrosine phosphate 1B (PTP1B) and IkappaB kinase beta (IKK-beta), is a novel insulin sensitizer with potential anticancer activity for the study of type 2 diabetes and breast cancer. Target: IkappaB/IKK, Phosphatase. Smiles:...
| Schlagworte: | PTP-112, PTP112, PTP 112 |
| Anwendung: | Targets tyrosine-protein phosphatase non-receptor type 1 [EC:3.1.3.48] (PTPN1, PTP1B) |
| CAS | 251303-04-5 |
| MW: | 559.51 D |
ab 83,00 €
Bakuchiol
Artikelnummer: TGM-T3400-1mL
Description: Bakuchiol possesses anti-tumor,and anti-helmenthic properties. It has cytotoxic activity, mainly due to its DNA polymerase1 inhibiting activity. Bakuchiol has anti-bacterial activity against oral pathogens, has great potential for use in food additives and mouthwash for preventing and treating dental...
| Anwendung: | PTP1B inhibitor |
| CAS | 10309-37-2 |
| MW: | 256.38 D |
ab 49,00 €
PTP1B-IN-2
Artikelnummer: TGM-T4256-100mg
Description: PTP1B-IN-2 is an effective protein tyrosine phosphatase 1B (PTP1B) inhibitor(IC50=50 nM). Target: Phosphatase. Smiles: COC(=O)CN(c1ccc(CN(c2ccc(OCc3ccc(C)cc3)c(c2)C(=O)OC)S(=O)(=O)Cc2ccccc2)cc1)S(C)(=O)=O. References: Liu P, et al. Discovery of novel, high potent, ABC type PTP1B inhibitors with TCPTP...
| Anwendung: | PTP1B inhibitor |
| CAS | 1919853-46-5 |
| MW: | 680.79 D |
ab 42,00 €
Anti-PTPN1
Artikelnummer: CSB-PA003883.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-PTPN1, Anti-PTP1B, Anti-PTP-1B, EC=3.1.3.48, Anti-Protein-tyrosine phosphatase 1B, Anti-Tyrosine-protein phosphatase... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat, monkey |
ab 126,00 €
Anti-Phospho-PTPN1 (Ser50)
Artikelnummer: CSB-PA129081.100
Host Species: Rabbit. Isotype: IgG. Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits...
| Schlagworte: | Anti-phospho-PTPN1, Anti-phospho-PTP1B, Anti-phospho-PTP-1B, EC=3.1.3.48, Anti-phospho-Protein-tyrosine phosphatase 1B,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat, monkey |
340,00 €