Zu "K05660" wurden 60 Artikel gefunden!
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Anti-ABCB5
Artikelnummer: 600-401-A77
Protein function: Plasma membrane transporter able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. Responsible for the resistance to doxorubicin of a subset of malignant melanomas. [The UniProt Consortium]
| Schlagworte: | Anti-ABCB5, Anti-ABCB5 P-gp, Anti-P-glycoprotein ABCB5, Anti-ATP-binding cassette sub-family B member 5 |
| Anwendung: | ELISA, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 180,00 €
CP 100,356 (hydrochloride)
Artikelnummer: Cay32853-5
CP 100,356 is an inhibitor of P-glycoprotein (P-gp, IC50 = 0.5 µM for inhibition of calcein AM transport in MDCKII monolayers). It is selective for P-gp over multidrug resistance-associated protein 2 (MRP2) at 15 µM, as well as the cytochrome P450 (CYP) isoforms CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4 (IC50s =...
| Schlagworte: | 4-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-6,7-dimethoxy-2-quinazolinamine,... |
| Anwendung: | P-glycoprotein inhibitor |
| CAS | 142715-48-8 |
| MW: | 597.1 D |
ab 93,00 €
Anti-ABCB5
Artikelnummer: ARG56227.100
Protein function: Drug efflux transporter present in a number of stem cells that acts as a regulator of cellular differentiation. Able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. Specifically present in limbal stem cells, where it plays a key role in corneal development...
| Schlagworte: | Anti-ABCB5, Anti-ABCB5 P-gp, Anti-P-glycoprotein ABCB5, Anti-ATP-binding cassette sub-family B member 5 |
| Anwendung: | WB, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
616,00 €
Anti-ABCB5, Internal
Artikelnummer: ARG64411.100
Protein function: Drug efflux transporter present in a number of stem cells that acts as a regulator of cellular differentiation. Able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. Specifically present in limbal stem cells, where it plays a key role in corneal development...
| Schlagworte: | Anti-ABCB5, Anti-ABCB5 P-gp, Anti-P-glycoprotein ABCB5, Anti-ATP-binding cassette sub-family B member 5 |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
871,00 €
Anti-ABCB5, clone 11A2
Artikelnummer: ARG66172.100
Protein function: Drug efflux transporter present in a number of stem cells that acts as a regulator of cellular differentiation. Able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. Specifically present in limbal stem cells, where it plays a key role in corneal development...
| Schlagworte: | Anti-ABCB5, Anti-ABCB5 P-gp, Anti-P-glycoprotein ABCB5, Anti-ATP-binding cassette sub-family B member 5 |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
616,00 €
Bacoside A3
Artikelnummer: Cay11824-5
Bacoside A3 is a triterpenoid saponin first isolated from B. monniera. Bacoside A3 inhibits the ATP-binding cassette transporter P-glycoprotein (P-gp), decreasing efflux 4-fold compared with control in vitro. An extract containing bacoside A3 and bacopaside II (4 and 1.3 µg/mg extract, respectively) administered for...
| Schlagworte: | Bacopa Pgp, (3beta,16beta,23R)-16,23:16,30-diepoxy-20-hydroxydammar-24-en-3-yl... |
| Anwendung: | P-glycoprotein inhibitor |
| CAS | 157408-08-7 |
| MW: | 929.1 D |
857,00 €
Human ABCB5 ELISA Kit
Artikelnummer: G-HUFI00914.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Anti-ATP-Binding Cassette Sub-Family B Member 1 (ABCB1)
Artikelnummer: 600-401-967
Protein function: Plasma membrane transporter able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. Responsible for the resistance to doxorubicin of a subset of malignant melanomas. [The UniProt Consortium]
| Schlagworte: | Anti-ABCB5, Anti-ABCB5 P-gp, Anti-P-glycoprotein ABCB5, Anti-ATP-binding cassette sub-family B member 5 |
| Anwendung: | ELISA, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, monkey, dog, mouse, rat |
ab 180,00 €
Anti-ABCB5
Artikelnummer: NSJ-R35491-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: ATP-binding cassette, sub-family B (MDR/TAP), member 5 Protein function: Drug efflux transporter present in a number of stem cells that acts as a regulator of cellular differentiation. Able to...
| Schlagworte: | Anti-ABCB5, Anti-ABCB5 P-gp, Anti-P-glycoprotein ABCB5, Anti-ATP-binding cassette sub-family B member 5, ABCB5 Antibody |
| Anwendung: | WB, ELISA (peptide), FC |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €
MC70
Artikelnummer: Cay21330-1
MC70 is a P-glycoprotein (P-gp) inhibitor. It inhibits the efflux of [3H]vinblastine by ATP binding cassette subfamily B member 1 (ABCB1) in Caco-2 colon cancer cells (EC50 = 0.05 µM). MC70 also inhibits the efflux of rhodamine-123 (Cay-16672) and calcein-AM (Cay-14948) by breast cancer resistant protein (BCRP) and...
| Schlagworte: | 4'-[(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)methyl]-[1,1'-biphenyl]-4-ol |
| Anwendung: | P-gp inhibitor |
| CAS | 1031367-64-2 |
| MW: | 375.5 D |
ab 85,00 €
Anti-ABCB5
Artikelnummer: NSJ-F49442-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. ABCB5 belongs to the ATP-binding cassette (ABC) transporter superfamily of integral membrane proteins. These proteins participate in ATP-dependent transmembrane transport of structurally diverse molecules ranging from small ions, sugars, and peptides to more complex...
| Schlagworte: | Anti-ABCB5, Anti-ABCB5 P-gp, Anti-P-glycoprotein ABCB5, Anti-ATP-binding cassette sub-family B member 5, ABCB5 Antibody |
| Anwendung: | WB, FC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
PGP-4008
Artikelnummer: Cay20901-1
PGP-4008 is a selective inhibitor of P-glycoprotein (P-gp) that does not affect the activity of multidrug resistance-related protein 1 (MRP1). It is effective in vitro and, when delivered intraperitoneally, in vivo, inhibiting tumor growth when given with doxorubicin (Cay-15007). PGP-4008 also enhances the ability...
| Schlagworte: | N-[2,3-dihydro-1-(phenylmethyl)-1H-pyrrolo[2,3-b]quinolin-4-yl]-benzeneacetamide |
| CAS | 365565-02-2 |
| MW: | 393.5 D |
ab 73,00 €