Zu "K05638" wurden 112 Artikel gefunden!
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Nrf2 Transcription Factor Assay Kit
Artikelnummer: Cay600590-96
Nuclear factor E2-related factor 2 (Nrf2) is a transcription factor that plays a key role in maintaining redox homeostasis via its interaction with a cysteine-rich protein Kelch-like ECH-associated protein 1 (Keap1). In resting cells, Nrf2 and Keap1 form a tight complex, which is targeted for degradation by...
| Schlagworte: | GABPA, HEBP1, NF-E2-related factor 2, Nuclear Factor Erythroid 2-related factor 2 |
| Anwendung: | DNA binding assay |
661,00 €
Human NFE2L2 (Nuclear Factor, Erythroid Derived 2 Like...
Artikelnummer: ELK-ELK6819.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human NFE2L2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human NFE2L2....
| Schlagworte: | Nrf-2, HEBP1, NFE2-related factor 2, NF-E2-related factor 2, Nuclear factor erythroid 2-related factor 2, Nuclear factor,... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Rat NFE2L2 (Nuclear Factor, Erythroid Derived 2 Like...
Artikelnummer: ELK-ELK8043.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat NFE2L2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat NFE2L2. Next,...
| Schlagworte: | NFE2-related factor 2, NF-E2-related factor 2, Nuclear factor, erythroid derived 2, like 2, Nuclear factor erythroid... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
ab 365,00 €
Mouse NFE2L2 (Nuclear Factor, Erythroid Derived 2 Like...
Artikelnummer: ELK-ELK8104.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse NFE2L2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse NFE2L2....
| Schlagworte: | NFE2-related factor 2, NF-E2-related factor 2, Nuclear factor, erythroid derived 2, like 2, Nuclear factor erythroid... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 365,00 €
Anti-Nrf2
Artikelnummer: ELK-EA259.50
Nuclear factor (erythroid-derived 2)-like 2, also known as NFE2L2 or Nrf2, is a transcription factor that in humans is encoded by the NFE2L2 gene. Small amounts of constitutive nuclear NRF2 maintain cellular homeostasis through regulation of basal expression of antioxidant response genes. Protein function:...
| Schlagworte: | Anti-HEBP1, Anti-Nrf-2, Anti-NFE2-related factor 2, Anti-NF-E2-related factor 2, Anti-Nuclear factor, erythroid derived 2,... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
169,00 €
Anti-Nrf2
Artikelnummer: ELK-EA346.100
Nuclear factor (erythroid-derived 2)-like 2, also known as NFE2L2 or Nrf2, is a transcription factor that in humans is encoded by the NFE2L2 gene. Small amounts of constitutive nuclear NRF2 maintain cellular homeostasis through regulation of basal expression of antioxidant response genes. Protein function:...
| Schlagworte: | Anti-HEBP1, Anti-Nrf-2, Anti-NFE2-related factor 2, Anti-NF-E2-related factor 2, Anti-Nuclear factor, erythroid derived 2,... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
283,00 €
L-Sulforaphane
Artikelnummer: Cay14797-10
L-Sulforaphane is an isothiocyanate derived from the natural compound glucoraphanin, which is abundant in cruciferous vegetables, including broccoli. It has powerful antioxidant, anti-inflammatory, and anti-carcinogenic effects. L-Sulforaphane, at 40 µM, activates nuclear factor erythroid 2-related factor 2- (Nrf2)...
| Schlagworte: | (R)-Sulforaphane, 1-isothiocyanato-4-[(R)-methylsulfinyl]-butane |
| Anwendung: | Nrf2 activator, Chemopreventive agent |
| CAS | 142825-10-3 |
| MW: | 177.3 D |
ab 61,00 €
4-octyl Itaconate
Artikelnummer: Cay25374-100
4-octyl Itaconate is a prodrug form of itaconate, an endogenous cellular metabolite produced via decarboxylation of cis-aconitate by the enzyme encoded by IRG1. It is hydrolyzed to itaconate by esterases in C2C12 cells and LPS-activated mouse macrophages where it acts as a regulator of macrophage function with...
| Schlagworte: | 2-methylene-butanedioic acid, 4-octyl ester |
| Anwendung: | Prodrug, Nrf2 stabilization |
| CAS | 3133-16-2 |
| MW: | 242.3 D |
ab 54,00 €
R-Sulforaphane
Artikelnummer: LKT-S8046.10
A chiral natural product from broccoli. Also an inducer of phase II enzymes.
| Schlagworte: | L-Sulforaphane |
| Anwendung: | Chemopreventive agent |
| CAS | 142825-10-3 |
| MW: | 177,29 D |
ab 458,00 €
ARE Reporter Kit (Nrf2 Antioxidant Pathway )
Artikelnummer: BPS-60514
The ARE Reporter kit is designed for monitoring the activity of the Nrf2 antioxidant pathway in cultured cells. The kit contains a transfection-ready ARE luciferase reporter vector, which is an Nrf2 pathway-responsive reporter. This reporter contains a firefly luciferase gene under the control of multimerized ARE...
| Schlagworte: | HEBP1, Nrf-2, NFE2-related factor 2, NF-E2-related factor 2, Nuclear factor erythroid 2-related factor 2, Nuclear factor,... |
| Anwendung: | Nrf2 pathway activity studies, activator/inhibitor screening |
956,00 €
CDDO methyl ester
Artikelnummer: Cay11883-5
The synthetic oleanane triterpenoid CDDO (Cay-81035) is a Nrf2 activator that inhibits proliferation and induces differentiation and apoptosis in various cancer cells. The C-28 methyl ester of CDDO (CDDO methyl ester) blocks the cellular synthesis of inducible nitric oxide synthase (iNOS) and inducible COX-2 in...
| Schlagworte: | Bardoxolone methyl, NSC 713200, RTA 402, TP-155, 2-cyano-3,12-dioxo-oleana-1,9(11)-dien-28-oic acid, methyl ester |
| Anwendung: | Apoptosis inducer |
| CAS | 218600-53-4 |
| MW: | 505.7 D |
ab 74,00 €
Nrf2 (Human) Reporter Assay System
Artikelnummer: IB-IB10001
Protein function: Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating...
| Schlagworte: | NRF2, HEBP1, NFE2L2, NFE2-related factor 2, NF-E2-related factor 2, Nuclear factor erythroid 2-related factor 2, Nuclear... |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.448,00 €