Zu "K05547" wurden 52 Artikel gefunden!
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3,3',5'-Triiodo-L-thyronine
Artikelnummer: Cay17598-50
3,3',5'-Triiodo-L-thyronine, also known as reverse T3 (rT3), is a thyroid hormone generated by deiodination of the prohormone thyroxine. It is about 1,000-fold less active at the thyroid hormone receptors TRalpha and TRbeta than 3,3',5-triiodo-L-thyronine (Cay-16028) and commonly described as inactive. However, high...
| Schlagworte: | 3,3',5'-T3, Reverse T3, rT3, O-(4-hydroxy-3,5-diiodophenyl)-3-iodo-L-tyrosine |
| Anwendung: | TR Delta alpha1 activator |
| CAS | 5817-39-0 |
| MW: | 651 D |
ab 114,00 €
Human THRa (Thyroid Hormone Receptor Alpha) ELISA Kit
Artikelnummer: ELK-ELK3974.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human THRa. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human THRa. Next,...
| Schlagworte: | THRA, EAR7, EAR-7, c-erbA-1, c-erbA-alpha, V-erbA-related protein 7, Thyroid hormone receptor alpha, Nuclear receptor... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Rat THRa (Thyroid Hormone Receptor Alpha) ELISA Kit
Artikelnummer: ELK-ELK6646.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat THRa. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat THRa. Next,...
| Schlagworte: | Thra, c-erbA-1, c-erbA-alpha, Thyroid hormone receptor alpha, Nuclear receptor subfamily 1 group A member 1 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
ab 365,00 €
3,5-Diiodo-L-thyronine
Artikelnummer: Cay35212-500
3,5-Diiodo-L-thyronine (3,5-T2) is a thyroid hormone metabolite. It binds to thyroid hormone receptor alpha1 (TRalpha1), TRbeta1, and TRbeta2 (EC50s = 0.8, 0.79, and 0.1 µM, respectively, in cell-free assays). 3,5-T2 (1 pM) stimulates oxygen consumption in perfused livers isolated from rats with hypothyroidism...
| Schlagworte: | 3,5-Diiodothyronine, 3,5-T2, NSC 90469, O-(4-hydroxyphenyl)-3,5-diiodo-L-tyrosine |
| Anwendung: | Thyroid hormone metabolite |
| CAS | 1041-01-6 |
| MW: | 525.1 D |
ab 77,00 €
L-Thyroxine
Artikelnummer: Cay14116-500
L-Thyroxine is a synthetic form of the thyroid hormone thyroxine. In vivo, L-thyroxine (0.9 and 2.7 µg) inhibits synthesis and release of thyrotropin induced by thyrotropin-releasing hormone (Cay-22917) from the anterior pituitary in mice. It also reverses decreases in levels of circulating thymic serum factor (FTS)...
| Schlagworte: | L-T4, Levothyroxine, NSC 36397, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine |
| Anwendung: | Thyroid hormone receptor agonist |
| CAS | 51-48-9 |
| MW: | 776.9 D |
ab 60,00 €
Thyroid Hormone Receptor Antagonist (1-850)
Artikelnummer: Cay17248-10
Thyroid hormone receptor antagonist (1-850) competitively blocks T3 binding to both TRalpha and TRbeta (IC50s = 1.5 µM), demonstrating ~1,000-fold lower affinity for TRalpha in intact cells compared with T3. This compound is specific, showing no effect on the activity of the related retinoic acid receptor...
| Schlagworte: | 2-[1-(4-nitrophenyl)-4-piperidinylidene]-acetic acid-2-[[[3-(trifluoromethyl)phenyl]amino]carbonyl]hydrazide |
| Anwendung: | THRB / THRA antagonist |
| CAS | 251310-57-3 |
| MW: | 463.4 D |
ab 61,00 €
3,3',5-Triiodo-L-thyronine (sodium salt hydrate)
Artikelnummer: Cay16028-250
3,3',5-Triiodo-L-thyronine (T3) is a thyroid hormone. It is produced by 5'-monodeiodination of the prohormone thyroxine (T4) in various tissues, including liver and kidney. T3 is an agonist of thyroid hormone receptors TRalpha and TRbeta (Kis = 2.3 nM for both) that modulates diverse biological properties, including...
| Schlagworte: | L-3,3',5-Triiodothyronine, Liothyronine, T3, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine, monosodium salt, hydrate |
| Anwendung: | Thyroid hormone receptor agonist |
| CAS | 345957-19-9 |
| MW: | 673 D |
ab 60,00 €
Anti-Thyroid Hormone Receptor alpha, Internal
Artikelnummer: ARG64299.100
Protein function: Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine. [The UniProt Consortium]
| Schlagworte: | Anti-EAR7, Anti-THRA, Anti-EAR-7, Anti-c-erbA-1, Anti-c-erbA-alpha, Anti-V-erbA-related protein 7, Anti-Thyroid hormone... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
784,00 €
Human THRA / Thyroid Hormone Receptor alpha ELISA Kit
Artikelnummer: G-HUFI01683.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
641,00 €
TRalpha (human) Reporter Assay Kit
Artikelnummer: IB-IB01002
This nuclear receptor assay system utilizes proprietary human cells engineered to provide constitutive, high-level expression of the human thyroid hormone receptor alpha (NR1A1), a ligand-dependent transcription factor commonly referred to as TRalpha. INDIGO's reporter cells include the luciferase reporter gene...
| Schlagworte: | THRA, EAR7, EAR-7, c-erbA-1, c-erbA-alpha, V-erbA-related protein 7, Thyroid hormone receptor alpha, Nuclear receptor... |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
3.802,00 €
TR (human) Reporter Assays Panel
Artikelnummer: IB-IB01201-48P
INDIGO's panel of TR reporter assays utilizes non-human mammalian cells engineered to express human thyroid hormone receptors alpha (NR1A3) and beta (NR1A2), ligand-dependent transcription factors commonly referred to as TRalpha and TRbeta. INDIGO's TR reporter cells include the luciferase reporter gene functionally...
| Schlagworte: | thyroid hormone receptor alpha (NR1A1), thyroid hormone receptor beta (NR1A2), Tralpha, TRbeta |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
1.894,00 €
Anti-Thyroid Hormone Receptor alpha 2, clone 1330
Artikelnummer: 209-301-E44
Anti-Thyroid Hormone Receptor alpha 2 Monoclonal Antibody is directed against human thyroid hormone receptor alpha 2 protein. Thyroid Hormone Receptor alpha 2 antibodies are puriifed by Protein G chromatography. Reactivity is expected from the following species based on 100% sequence homology: bovine, canine, mouse...
| Schlagworte: | Anti-EAR7, Anti-THRA, Anti-EAR-7, Anti-c-erbA-1, Anti-c-erbA-alpha, Anti-V-erbA-related protein 7, Anti-Thyroid hormone... |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
698,00 €