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Mouse IRF3 (Interferon Regulatory Factor 3) ELISA Kit
Mouse IRF3 (Interferon Regulatory Factor 3) ELISA Kit

Artikelnummer: ELK-ELK2854.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse IRF3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse IRF3. Next,...
Schlagworte: Irf3, IRF-3, Interferon regulatory factor 3
Anwendung: ELISA
Spezies-Reaktivität: mouse
ab 365,00 €
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Human IRF3 (Interferon Regulatory Factor 3) ELISA Kit
Human IRF3 (Interferon Regulatory Factor 3) ELISA Kit

Artikelnummer: ELK-ELK2074.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human IRF3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human IRF3. Next,...
Schlagworte: IRF-3, Interferon regulatory factor 3
Anwendung: ELISA
Spezies-Reaktivität: human
ab 365,00 €
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STING Agonist C11
STING Agonist C11

Artikelnummer: Cay27886-1

STING agonist C11 is an agonist of the stimulator of interferon genes (STING) pathway. It induces secretion of type I IFN from THF and MM6 cells when used at a concentration of 50 µM. STING agonist C11 induces phosphorylation of IFN regulatory factor 3 (IRF3) and increases expression of IFIT1 and viperin, but not...
Schlagworte: N-[(methylamino)carbonyl]-alpha-[[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]thio]-benzeneacetamide
Anwendung: Stimulator of interferon genes (STING) pathway agonist
CAS 875863-22-2
MW: 382.4 D
ab 83,00 €
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KIN1148
KIN1148

Artikelnummer: Cay38980-1

KIN1148 is an IFN regulating factor 3 (IRF3) activator and adjuvant. It increases the mRNA expression of the genes encoding IFN-stimulated gene 54 (ISG54) and 2'-5'-oligoadenylate synthase-like (OASL) protein in PH5CH8 cells and increases chemokine (C-X-C motif) ligand 10 (CXCL10) production in phorbol 12-myristate...
Schlagworte: N-benzo[1,2-d:3,4-d']bisthiazol-2-yl-2-naphthalenecarboxamide
Anwendung: IRF3 activator, adjuvant
CAS 1428729-56-9
MW: 361.4 D
ab 104,00 €
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Anti-IRF3
Anti-IRF3

Artikelnummer: A300-426A

Protein function: Key transcriptional regulator of type I interferon (IFN)-dependent immune responses which plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an...
Schlagworte: Anti-IRF3, Anti-IRF-3, Anti-Interferon regulatory factor 3
Anwendung: WB, IHC
Wirt: Rabbit
Spezies-Reaktivität: human
ab 164,00 €
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Anti-IRF3
Anti-IRF3

Artikelnummer: A303-384A

Protein function: Key transcriptional regulator of type I interferon (IFN)-dependent immune responses which plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an...
Schlagworte: Anti-Irf3, Anti-IRF-3, Anti-Interferon regulatory factor 3
Anwendung: WB, IP
Wirt: Rabbit
Spezies-Reaktivität: mouse
ab 164,00 €
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Cridanimod (sodium salt)
Cridanimod (sodium salt)

Artikelnummer: Cay27884-10

Cridanimod is an inducer of type I interferon (IFN) production. It induces IRF3 phosphorylation, IFN-beta production, and NF-kappaB activation in wild-type, but not in stimulator of interferon genes (STING) mutant, murine macrophages. In vivo, cridanimod (112-1,792 mg/kg) increases plasma levels of IFN in weanling...
Schlagworte: 10-Carboxymethyl-9-Acridanone, 9-oxo-10(9H)-acridineacetic acid, monosodium salt
Anwendung: Type I interferon (IFN) production inducer, IRF3 phosphorylation inducer
CAS 58880-43-6
MW: 275.2 D
ab 43,00 €
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Anti-IRF3
Anti-IRF3

Artikelnummer: ARG56578.50

Protein function: Key transcriptional regulator of type I interferon (IFN)-dependent immune responses which plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an...
Schlagworte: Anti-IRF3, Anti-IRF-3, Anti-Interferon regulatory factor 3
Anwendung: ICC, IF, IHC (paraffin), WB
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
520,00 €
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Anti-IRF3, clone 3F10
Anti-IRF3, clone 3F10

Artikelnummer: ARG56940.50

Protein function: Key transcriptional regulator of type I interferon (IFN)-dependent immune responses which plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an...
Schlagworte: Anti-IRF3, Anti-IRF-3, Anti-Interferon regulatory factor 3
Anwendung: WB, IP
Wirt: Mouse
Spezies-Reaktivität: human
488,00 €
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Anti-phospho-IRF3 (Ser396)
Anti-phospho-IRF3 (Ser396)

Artikelnummer: ARG57516.50

Protein function: Key transcriptional regulator of type I interferon (IFN)-dependent immune responses which plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an...
Schlagworte: Anti-phospho-IRF3, Anti-phospho-IRF-3, Anti-phospho-Interferon regulatory factor 3
Anwendung: WB
Wirt: Rabbit
Spezies-Reaktivität: human
488,00 €
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KIN1408
KIN1408

Artikelnummer: Cay21790-10

KIN1408 is a small molecule activator of the RIG-1-like receptor (RLR) pathway that has antiviral activity. It induces interferon regulatory factor 3 (IRF3) activation and translocation into the nucleus in a concentration-dependent manner in HEK293 cells without inducing cellular toxicity. KIN1408 induces expression...
Schlagworte: 7-[[4-(difluoromethoxy)phenyl][(5-methoxy-2-benzothiazolyl)amino]methyl]-8-quinolinol
Anwendung: IRF3 activator
CAS 1903800-11-2
MW: 479.5 D
ab 125,00 €
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IRF3 (human, recombinant)
IRF3 (human, recombinant)

Artikelnummer: Cay22811-100

Interferon regulatory factor 3 (IRF3) is a member of the IRF family. It plays a crucial role in activation of innate immunity and inflammation in response to viral infection, functioning as a molecular switch for antiviral activity. Double-stranded RNA generated during a viral infection leads to IRF3 activation by...
Schlagworte: IRF-3 {ECO:0000303|PubMed:9566918}, IRF-3 {ECO:0000303|PubMed:9566918}, Interferon regulatory factor 3...
Anwendung: Cell based assays, electrophoresis, IP, MS, WB
649,00 €
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