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Zu "K05410" wurden 49 Artikel gefunden!
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Artikelnummer: ELK-ELK4375.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human TBK1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human TBK1. Next,...
Schlagworte: | T2K, TANK-binding kinase 1, NF-kappa-B-activating kinase, Serine/threonine-protein kinase TBK1 |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: AG-CR1-3579-M010
Soluble in DMSO or dimethylformamide. Antiallergic. Anti-inflammatory. Antagonizes the angiogenic and mitogenic activity of FGF-1 through S100A13. Inhibits FGF-1 release. Binds to HSP90. Inhibits C-terminal chaperone activity. Induces an increase in nonsense-containing mRNAs amount in treated cells, leading to...
Schlagworte: | 2-Amino-7-(1-methylethyl)-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxylic acid, AA 673, Amoxanox, CHX 3674 |
Anwendung: | TBK1 / IKKE inhibitor |
CAS | 68302-57-8 |
MW: | 298,3 D |
ab 66,00 €
Artikelnummer: Cay19916-1
MRT67307 is a kinase inhibitor that has been shown to inhibit TBK1, MARK1-4, IKKepsilon, and NUAK1 (IC50 values are 19, 27-52, 160, and 230 nM, respectively), the salt-inducible kinases (SIKs, IC50s = 250, 67, and 430 nM for SIK1, SIK2, and SIK3, respectively) and ULK1 and ULK2 (IC50s = 45 and 38 nM, respectively)....
Schlagworte: | N-[3-[[5-cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]-cyclobutanecarboxamide |
Anwendung: | IKKe / TBK-1 inhibitor |
MW: | 464.6 D |
ab 43,00 €
Artikelnummer: BPS-40286
Recombinant human TBK1, full length, with N-terminal GST-tag, expressed in Sf9 insect cells via a baculovirus expression system.
Schlagworte: | T2K, TANK-binding kinase 1, NF-kappa-B-activating kinase, Serine/threonine-protein kinase TBK1, |
Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
Exprimiert in: | insect cells |
Ursprungsart: | human |
MW: | 105 kD |
555,00 €
Artikelnummer: ARG57528.100
Protein function: Serine/threonine kinase that plays an essential role in regulating inflammatory responses to foreign agents. Following activation of toll-like receptors by viral or bacterial components, associates with TRAF3 and TANK and phosphorylates interferon regulatory factors (IRFs) IRF3 and IRF7 as well as...
Schlagworte: | Anti-T2K, Anti-NAK, Anti-TBK1, EC=2.7.11.1, Anti-TANK-binding kinase 1, Anti-NF-kappa-B-activating kinase,... |
Anwendung: | ICC, IF, IHC (paraffin), WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
624,00 €
Artikelnummer: A300-093A
Protein function: Serine/threonine kinase that plays an essential role in regulating inflammatory responses to foreign agents. Following activation of toll-like receptors by viral or bacterial components, associates with TRAF3 and TANK and phosphorylates interferon regulatory factors (IRFs) IRF3 and IRF7 as well as...
Schlagworte: | Anti-NAK, Anti-T2K, Anti-TBK1, EC=2.7.11.1, Anti-TANK-binding kinase 1, Anti-NF-kappa-B-activating kinase,... |
Anwendung: | WB, IP |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 164,00 €
Artikelnummer: Cay22817-50
TANK-binding kinase 1 (TBK1) is a non-canonical inhibitor of NF-kappaB kinase (IKK) that has an essential role in regulating inflammatory responses to pathogens. Following activation of toll-like receptors by viral DNA, TBK1 interacts with various partners such as STING, MAVS, and TANK to phosphorylate and activate...
Schlagworte: | T2K, T2K, TANK-binding kinase 1, TANK-binding kinase 1, NF-kappa-B-activating kinase, NF-kappa-B-activating kinase,... |
Anwendung: | ELISA, WB, Enzyme activity |
Exprimiert in: | Insect cells |
Ursprungsart: | human |
896,00 €
Artikelnummer: G-MOFI00399.96
Anwendung: | ELISA |
Spezies-Reaktivität: | mouse |
694,00 €
Artikelnummer: 200-301-I22
Anti-TBK1 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-TBK1 from Human, Mouse, cow,dog and rat based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-TBK1 from other sources has not been determined. Protein function:...
Schlagworte: | Anti-T2K, Anti-NAK, Anti-TBK1, EC=2.7.11.1, Anti-TANK-binding kinase 1, Anti-NF-kappa-B-activating kinase,... |
Anwendung: | WB |
Wirt: | Mouse |
Spezies-Reaktivität: | human, mouse |
791,00 €
Artikelnummer: NSJ-R31230
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Serine/threonine-protein kinase TANK-binding kinase 1 or NF-kappa-B-activating kinase is an enzyme that in humans is encoded by the TBK1 gene. The gene was assigned to human chromosome 12q14.2. Serine/threonine kinases plays an essential role in regulating...
Schlagworte: | Anti-T2K, Anti-TANK-binding kinase 1, Anti-NF-kappa-B-activating kinase, Anti-Serine/threonine-protein kinase TBK1, TBK1... |
Anwendung: | WB, IHC (paraffin) |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
755,00 €
Artikelnummer: NSJ-R36186-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: TANK-binding kinase 1, NAK, NF-kB-activating kinase Protein function: Serine/threonine kinase that plays an essential role in regulating inflammatory responses to foreign agents. Following...
Schlagworte: | Anti-NAK, Anti-T2K, Anti-TBK1, EC=2.7.11.1, Anti-TANK-binding kinase 1, Anti-NF-kappa-B-activating kinase,... |
Anwendung: | WB, ELISA (peptide) |
Wirt: | Goat |
Spezies-Reaktivität: | human |
755,00 €
Artikelnummer: NSJ-F45532-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Serine/threonine protein involved in the signaling cascade converging to the activation of the transcription factor NF-kappa-B. May function as an IKK kinase, playing an essential role in the transcription of a subset of a TNF-alpha-induced genes. Also mediates production...
Schlagworte: | Anti-T2K, Anti-Tbk1, EC=2.7.11.1, Anti-TANK-binding kinase 1, Anti-Serine/threonine-protein kinase TBK1, Tbk1 Antibody |
Anwendung: | WB, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | mouse |
ab 326,00 €