Zu "K05410" wurden 69 Artikel gefunden!
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Anti-Recombinant Phospho-TBK1/NAK (Ser172), clone A843
Artikelnummer: E-AN302119L.100
TBK1(tumor necrosis factor (TNF) receptor-associated factor NF-kB activator (TANK)-binding kinase 1), also named as NF-kB-activating kinase (NAK), T2K, is a multimeric kinase that modulates inflammation and autophagy. It is a ubiquitously expressed serine-threonine kinase belonging to the 'noncanonical IkB kinases'...
| Schlagworte: | Anti-T2K, Anti-TBK1, Anti-TANK-binding kinase 1, Anti-NF-kappa-B-activating kinase, Anti-Serine/threonine-protein kinase... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
ab 304,00 €
MRT67307 (hydrochloride)
Artikelnummer: Cay19916-1
MRT67307 is a kinase inhibitor that has been shown to inhibit TBK1, MARK1-4, IKKepsilon, and NUAK1 (IC50 values are 19, 27-52, 160, and 230 nM, respectively), the salt-inducible kinases (SIKs, IC50s = 250, 67, and 430 nM for SIK1, SIK2, and SIK3, respectively) and ULK1 and ULK2 (IC50s = 45 and 38 nM, respectively)....
| Schlagworte: | N-[3-[[5-cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]-cyclobutanecarboxamide |
| Anwendung: | IKKe / TBK-1 inhibitor |
| MW: | 464.6 D |
ab 49,00 €
Amlexanox
Artikelnummer: AG-CR1-3579-M010
Soluble in DMSO or dimethylformamide. Antiallergic. Anti-inflammatory. Antagonizes the angiogenic and mitogenic activity of FGF-1 through S100A13. Inhibits FGF-1 release. Binds to HSP90. Inhibits C-terminal chaperone activity. Induces an increase in nonsense-containing mRNAs amount in treated cells, leading to...
| Schlagworte: | 2-Amino-7-(1-methylethyl)-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxylic acid, AA 673, Amoxanox, CHX 3674 |
| Anwendung: | TBK1 / IKKE inhibitor |
| CAS | 68302-57-8 |
| MW: | 298,3 D |
ab 22,00 €
Anti-NAK / TBK1
Artikelnummer: ARG57528.100
Protein function: Serine/threonine kinase that plays an essential role in regulating inflammatory responses to foreign agents. Following activation of toll-like receptors by viral or bacterial components, associates with TRAF3 and TANK and phosphorylates interferon regulatory factors (IRFs) IRF3 and IRF7 as well as...
| Schlagworte: | Anti-T2K, Anti-NAK, Anti-TBK1, EC=2.7.11.1, Anti-TANK-binding kinase 1, Anti-NF-kappa-B-activating kinase,... |
| Anwendung: | ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
658,00 €
Anti-TBK1
Artikelnummer: A300-093A
Protein function: Serine/threonine kinase that plays an essential role in regulating inflammatory responses to foreign agents. Following activation of toll-like receptors by viral or bacterial components, associates with TRAF3 and TANK and phosphorylates interferon regulatory factors (IRFs) IRF3 and IRF7 as well as...
| Schlagworte: | Anti-NAK, Anti-T2K, Anti-TBK1, EC=2.7.11.1, Anti-TANK-binding kinase 1, Anti-NF-kappa-B-activating kinase,... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
TBK1 (human, recombinant)
Artikelnummer: Cay22817-50
TANK-binding kinase 1 (TBK1) is a non-canonical inhibitor of NF-kappaB kinase (IKK) that has an essential role in regulating inflammatory responses to pathogens. Following activation of toll-like receptors by viral DNA, TBK1 interacts with various partners such as STING, MAVS, and TANK to phosphorylate and activate...
| Schlagworte: | T2K, T2K, TANK-binding kinase 1, TANK-binding kinase 1, NF-kappa-B-activating kinase, NF-kappa-B-activating kinase,... |
| Anwendung: | ELISA, WB, enzyme activity |
| Exprimiert in: | Insect cells |
| Ursprungsart: | human |
992,00 €
Mouse Tbk1 ELISA Kit
Artikelnummer: G-MOFI00399.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
698,00 €
Anti-TBK1, clone 108A429
Artikelnummer: 200-301-I22
Anti-TBK1 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-TBK1 from Human, Mouse, cow,dog and rat based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-TBK1 from other sources has not been determined. Protein function:...
| Schlagworte: | Anti-T2K, Anti-NAK, Anti-TBK1, EC=2.7.11.1, Anti-TANK-binding kinase 1, Anti-NF-kappa-B-activating kinase,... |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse |
819,00 €
Anti-TBK1
Artikelnummer: NSJ-R31230
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Serine/threonine-protein kinase TANK-binding kinase 1 or NF-kappa-B-activating kinase is an enzyme that in humans is encoded by the TBK1 gene. The gene was assigned to human chromosome 12q14.2. Serine/threonine kinases plays an essential role in regulating...
| Schlagworte: | Anti-T2K, Anti-TANK-binding kinase 1, Anti-NF-kappa-B-activating kinase, Anti-Serine/threonine-protein kinase TBK1, TBK1... |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-TBK1
Artikelnummer: NSJ-R36186-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: TANK-binding kinase 1, NAK, NF-kB-activating kinase Protein function: Serine/threonine kinase that plays an essential role in regulating inflammatory responses to foreign agents. Following...
| Schlagworte: | Anti-NAK, Anti-T2K, Anti-TBK1, EC=2.7.11.1, Anti-TANK-binding kinase 1, Anti-NF-kappa-B-activating kinase,... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €
Anti-Tbk1
Artikelnummer: NSJ-F45532-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Serine/threonine protein involved in the signaling cascade converging to the activation of the transcription factor NF-kappa-B. May function as an IKK kinase, playing an essential role in the transcription of a subset of a TNF-alpha-induced genes. Also mediates production...
| Schlagworte: | Anti-T2K, Anti-Tbk1, EC=2.7.11.1, Anti-TANK-binding kinase 1, Anti-Serine/threonine-protein kinase TBK1, Tbk1 Antibody |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse |
ab 361,00 €
Anti-TBK1
Artikelnummer: NSJ-F50864-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway,...
| Schlagworte: | Anti-NAK, Anti-T2K, Anti-TBK1, EC=2.7.11.1, Anti-TANK-binding kinase 1, Anti-NF-kappa-B-activating kinase,... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €