Zu "K05403" wurden 38 Artikel gefunden!
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TSI-13-57
Artikelnummer: Cay45498-1
An inhibitor of Mal homodimerization and TLR signaling, inhibits the secretion of TNF-alpha induced by agonists of TLR9, -7, -2, or -4 in RAW 264.7 macrophages (IC50s = 2.7, 6.03, 7.37, and 6.38 µM, respectively), reduces LPS-induced increases in TNF-alpha levels in mouse plasma at 100 and 200 mg/kg. SMILES:...
| Schlagworte: | 4,4'-[3-[4-[2-(1-piperidinyl)ethoxy]phenyl]-1H-pyrazole-1,5-diyl]bis-phenol |
| Anwendung: | MAL (TIRAP) homodimerization / TLR signaling inhibitor |
| CAS | 2257427-45-3 |
| MW: | 455.56 D |
ab 402,00 €
Anti-TIRAP / Toll/interleukin-1 receptor...
Artikelnummer: NSJ-FY12140
Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. TIRAP antibody detects Toll/interleukin-1 receptor domain-containing adapter protein, encoded by the TIRAP gene on chromosome 11q24.2. TIRAP antibody is used to study this adaptor protein, also known as Mal (MyD88 adaptor-like). TIRAP plays an...
| Schlagworte: | Anti-TIRAP, Anti-Adaptor protein Wyatt, Anti-MyD88 adapter-like protein, Anti-Toll/interleukin-1 receptor... |
| Anwendung: | IHC, FC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
790,00 €
Anti-TIRAP / Mal (Isoform b), C-terminal
Artikelnummer: ARG63640.100
Protein function: Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and...
| Schlagworte: | Anti-MAL, Anti-TIRAP, Anti-MyD88-2, Anti-Adaptor protein Wyatt, Anti-MyD88 adapter-like protein, Anti-TIR... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
871,00 €
Anti-TIRAP, Internal
Artikelnummer: ARG63941.100
Protein function: Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and...
| Schlagworte: | Anti-MAL, Anti-TIRAP, Anti-MyD88-2, Anti-Adaptor protein Wyatt, Anti-MyD88 adapter-like protein, Anti-TIR... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
871,00 €
Human TIRAP ELISA Kit
Artikelnummer: G-HUFI01954.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Anti-TIRAP (Toll-interleukin 1 receptor domain-containing...
Artikelnummer: 200-401-A67
Protein function: Adapter involved in the TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and...
| Schlagworte: | Anti-Mal, Anti-Tirap, Anti-Adaptor protein Wyatt, Anti-MyD88 adapter-like protein, Anti-TIR domain-containing adapter... |
| Anwendung: | ELISA, IHC, IFM, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
848,00 €
Anti-TLR3
Artikelnummer: 200-401-FF9
Anti-TLR3 Antibody is purified by ion exchange chromatography. Cross reactivity with TLR3 from other sources has not been determined. Protein function: Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3...
| Schlagworte: | Anti-MAL, Anti-TIRAP, Anti-MyD88-2, Anti-Adaptor protein Wyatt, Anti-MyD88 adapter-like protein, Anti-TIR... |
| Anwendung: | ELISA, IFM, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
848,00 €
Anti-TIRAP (isoform b)
Artikelnummer: NSJ-R33776-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Toll-interleukin 1 receptor (TIR) domain-containing adapter protein, Mal Protein function: Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and...
| Schlagworte: | Anti-MAL, Anti-TIRAP, Anti-MyD88-2, Anti-Adaptor protein Wyatt, Anti-MyD88 adapter-like protein, Anti-TIR... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €
Anti-TIRAP
Artikelnummer: NSJ-R35486-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Toll-interleukin 1 receptor (TIR) domain containing adaptor protein Protein function: Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and...
| Schlagworte: | Anti-MAL, Anti-TIRAP, Anti-MyD88-2, Anti-Adaptor protein Wyatt, Anti-MyD88 adapter-like protein, Anti-TIR... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €
Anti-TIRAP
Artikelnummer: E-AB-17096.120
The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal...
| Schlagworte: | Anti-MAL, Anti-TIRAP, Anti-MyD88-2, Anti-Adaptor protein Wyatt, Anti-MyD88 adapter-like protein, Anti-TIR... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 89,00 €
Anti-TIRAP
Artikelnummer: ARG55409.50
Protein function: Adapter involved in the TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and...
| Schlagworte: | Anti-Mal, Anti-Tirap, Anti-Adaptor protein Wyatt, Anti-MyD88 adapter-like protein, Anti-TIR domain-containing adapter... |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
616,00 €
Anti-TIRAP
Artikelnummer: ATA-HPA054431.100
Protein function: Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and...
| Schlagworte: | Anti-MAL, Anti-TIRAP, Anti-MyD88-2, Anti-Adaptor protein Wyatt, Anti-MyD88 adapter-like protein, Anti-TIR... |
| Anwendung: | ICC, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €