Zu "K05398" wurden 47 Artikel gefunden!
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Pam3CSK4
Artikelnummer: TGM-TP1068-100mg
Description: Pam3CSK4 is a synthetic triacylated lipopeptide (LP) that mimics the acylated amino terminus of bacterial LPs. Smiles: [C@@H](NC([C@@H](NC([C@@H](NC([C@H](CSCC(COC(CCCCCCCCCC CCCCC)=O)OC(CCCCCCCCCCCCCCC)=O)NC(CCCCCCCCCCCCCCC)=O)=O)CO)=O)CCCCN)=O)(C(N[C@H](C(N[C@@H](CCCCN)C(O)=O)=O)CCCCN)=O)CCCCN....
| Schlagworte: | Pam3Cys-Ser-(Lys)4 |
| Anwendung: | TLR1/TLR2 agonist |
| CAS | 112208-00-1 |
| MW: | 1510.23 D |
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CU-T12-9
Artikelnummer: TGM-T15017-100mg
Description: CU-T12-9 is a potent TLR1/2 agonist(EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay). It acts by activating the NFkB pathway, upregulating proinflammatory cytokines, and enhancing TLR1 and TLR2 dimerization.CU-T12-9 activates both the innate and the adaptive immune systems. CU-T12-9 selectively activates...
| Anwendung: | TLR1/2 agonist |
| CAS | 1821387-73-8 |
| MW: | 362.31 D |
ab 106,00 €
CU-CPT22
Artikelnummer: TGM-T15020-100mg
Description: CU-CPT22 is the first probe for the complex between toll-like receptors TLR1 and TLR2. CU-CPT22 binds at the interface of TLR1 and TLR2 (IC50 = 0.58 µM). It competes with the synthetic triacylated lipoprotein (Pam3CSK4) binding to TLR1/2 (Ki: 0.41 µM). Target: TLR. Smiles:...
| Anwendung: | TLR1 antagonist |
| CAS | 1416324-85-0 |
| MW: | 362.37 D |
ab 45,00 €
MMG-11
Artikelnummer: TGM-T16123-2mg
Description: MMG-11 inhibits both TLR2/1 and TLR2/6 signaling (IC50s: 1.7 µM for Pam3CSK4-induced hTLR2/1 and 5.7 µM for Pam2CSK4-induced hTLR2/6 responses). MMG-11 is an effective and selective human TLR2 antagonist with low cytotoxicity. Target: Others. Smiles: CCOC(=O)c1ccc(CC(=O)c2ccc(O)c(O)c2O)o1. References:...
| Anwendung: | TLR1/2 antagonist |
| CAS | 313254-94-3 |
| MW: | 306.27 D |
58,00 €
SMU127
Artikelnummer: TGM-T35672-1mg
Description: SMU127 is an agonist of the toll-like receptor 1/2 (TLR1/2) heterodimer. Target: Others. Smiles: C(OCC)(=O)C=1C2=C(SC1NC(=O)N3CCN(C)CC3)CCC2. References: Chen, Z., Cen, X., Yang, J., et al.Structure-based discovery of a specific TLR1-TLR2 small molecule agonist from the ZINC drug library databaseChem....
| Anwendung: | TLR1/2 agonist |
| CAS | 903864-87-9 |
| MW: | 337.44 D |
ab 198,00 €
Pam3Cys-Ser-(Lys)4 . 3HCl
Artikelnummer: AG-CP3-0003-M002
Synthetic. Selective agonist of TLR1/TLR2 complex. Cell permeable, water soluble synthetic cationic lipohexapeptide analog of the immunologically active N-terminal portion of bacterial lipoprotein that potently activates monocytes and macrophages. Potent and effective immune adjuvant. Exerts strong local response,...
| Schlagworte: | Pam3CSK4, Pam3Cys-SKKKK, (S)-[2,3-Bis(palmitoyloxy)-(2- RS)-propyl]-N-palmitoyl-(R)-Cys-(S)-Ser-(S)-Lys 4-OH |
| Anwendung: | TLR1/TLR2 agonist |
| CAS | 112208-00-1 |
| MW: | 1619,7 D |
484,00 €
Anti-TLR1
Artikelnummer: CSB-PA080182.100
Host Species: Rabbit. Isotype: IgG. Buffer: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Affinity purification. Target Name: TLR1. Antigen Species: Human
| Schlagworte: | Anti-TIL, Anti-TLR1, Anti-CD281, Anti-KIAA0012, Anti-Toll-like receptor 1, Anti-Toll/interleukin-1 receptor-like protein,... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Anti-TLR1
Artikelnummer: CSB-PA953581.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: TLR1. Antigen Species: Human
| Schlagworte: | Anti-TIL, Anti-TLR1, Anti-CD281, Anti-KIAA0012, Anti-Toll-like receptor 1, Anti-Toll/interleukin-1 receptor-like protein,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 167,00 €
Toll-like receptor 1 (TLR1), partial, human, recombinant
Artikelnummer: CSB-YP023599HU.1
Organism: Homo sapiens (Human). Source: Yeast. Expression Region: 25-580aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: SEFLVDRSKN GLIHVPKDLS QKTTILNISQ NYISELWTSD ILSLSKLRIL IISHNRIQYL DISVFKFNQE LEYLDLSHNK LVKISCHPTV NLKHLDLSFN AFDALPICKE FGNMSQLKFL GLSTTHLEKS SVLPIAHLNI...
| Schlagworte: | TIL, TLR1, CD281, KIAA0012, Toll-like receptor 1, Toll/interleukin-1 receptor-like protein, Recombinant Human Toll-like... |
| Anwendung: | Activity not tested |
| Exprimiert in: | Yeast |
| Ursprungsart: | human |
| MW: | 65.2 kD |
ab 347,00 €
CU CPT 22
Artikelnummer: Cay15244-1
CU CPT 22 is an antagonist of toll-like receptor 1 (TLR1) and TLR2 heterodimers (TLR1/TLR2, Ki = 0.41 µM). It inhibits nitric oxide (NO) production induced by the TLR2 agonist Pam3CSK4 (Cay-24126) in RAW 264.7 cells (IC50 = 0.58 µM). It is selective for TLR1/TLR2 over TLR2/TLR6 and TLR3, -4, and -7 homodimers, as...
| Schlagworte: | 3,4,6-trihydroxy-2-methoxy-5-oxo-5H-benzocycloheptene-8-carboxylic acid, hexyl ester |
| Anwendung: | TLR1 antagonist |
| CAS | 1416324-85-0 |
| MW: | 362.4 D |
ab 78,00 €
Anti-TLR6
Artikelnummer: 600-401-FG3
Anti-TLR6 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with TLR6 from other sources has not been determined. Protein function: Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated...
| Schlagworte: | Anti-TIL, Anti-TLR1, Anti-CD281, Anti-KIAA0012, Anti-Toll-like receptor 1, Anti-Toll/interleukin-1 receptor-like protein |
| Anwendung: | ELISA, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
834,00 €
CU-T12-9
Artikelnummer: Cay32867-5
CU-T12-9 is an agonist of the toll-like receptor 1/2 (TLR1/2) heterodimer. It is selective for TLR1/2 over the TLR2/6 heterodimer in a secreted alkaline phosphatase (SEAP) assay at concentrations up to 10 µg/ml using HEK-Blue cells expressing human TLR2 and endogenously expressing both TLR1 and TLR6 and anti-TLR...
| Schlagworte: | N-methyl-4-nitro-2-[4-[4-(trifluoromethyl)phenyl]-1H-imidazol-1-yl]-benzenamine |
| Anwendung: | TLR1/2 agonist |
| CAS | 1821387-73-8 |
| MW: | 362.3 D |
ab 44,00 €