Zu "K05357" wurden 38 Artikel gefunden!
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Human VKORC1 (Vitamin K Epoxide Reductase Complex Subunit...
Artikelnummer: ELK-ELK5155.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human VKORC1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human VKORC1....
| Schlagworte: | VKORC1L1, VKORC1-like protein 1, Vitamin K epoxide reductase complex subunit 1-like protein 1 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
(±)-Warfarin
Artikelnummer: Cay13566-1
(±)-Warfarin (Cay-13566) is a vitamin K antagonist, a coumarin derivative, and a racemic mixture of (+)-warfarin (Cay-13526) and (-)-warfarin (Cay-13531). It is an anticoagulant that interferes with interconversion of vitamin K and vitamin K epoxide and the role of vitamin K in carboxylation of several clotting...
| Schlagworte: | (RS)-Warfarin, Athrombine K, NSC 59813, WARF 42, Zoocoumarin, 4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one |
| Anwendung: | Anti-coagulant |
| CAS | 81-81-2 |
| MW: | 308.3 D |
31,00 €
Dicoumarol
Artikelnummer: Cay20764-1
Dicoumarol is a competitive inhibitor of NADH:quinone oxidoreductase (NQO1) with IC50 values of 2.6 and 404 nM in the absence and presence of 2 µM BSA, respectively. It has antiproliferative activity against MIA PaCa-2 pancreas and HCT116 colon carcinoma cells (IC50s = 52 and 19 µM, respectively, after a 96 hour...
| Schlagworte: | NSC 17860, NSC 221570, NSC 41834, 3,3'-methylenebis[4-hydroxy-2H-1-benzopyran-2-one |
| Anwendung: | Vitamin K antagonist |
| CAS | 66-76-2 |
| MW: | 336.3 D |
ab 27,00 €
(-)-Warfarin
Artikelnummer: Cay13531-1
(-)-Warfarin is a component of (±)-warfarin (Cay-13566). It is an anticoagulant that interferes with interconversion of vitamin K and vitamin K epoxide and the role of vitamin K in carboxylation of several clotting cascade proteins, inhibiting the initiation of clotting. In vivo, (-)-warfarin slows formation of the...
| Schlagworte: | (S)-Warfarin, 4-hydroxy-3-[(1S)-3-oxo-1-phenylbutyl]-2H-1-benzopyran-2-one |
| Anwendung: | Anti-coagulant |
| CAS | 5543-57-7 |
| MW: | 308.3 D |
ab 94,00 €
(S)-Acenocoumarol
Artikelnummer: Cay9000336-1
Acenocoumarol is a short-lived oral anti-coagulant, which, like warfarin, functions by inhibiting vitamin K epoxide reductase. It has higher intrinsic anticoagulant potency than warfarin and phenprocoumon, when evaluated in vitro. Acenocoumarol has a single chiral center that gives rise to two different enantiomeric...
| Schlagworte: | (S)-Acenocoumarin, (S)-Nicoumalone, 4-hydroxy-3-[(1S)-1-(4-nitrophenyl)-3-oxobutyl]-2H-1-benzopyran-2-one |
| CAS | 66556-78-3 |
| MW: | 353.3 D |
ab 181,00 €
Vitamin K1 2,3-epoxide
Artikelnummer: Cay16017-500
Vitamin K is a dietary nutrient essential for the normal biosynthesis of factors that are required for blood clotting. It has also been shown to inhibit cell growth. Vitamin K1 2,3-epoxide is the inactive metabolite of vitamin K1. During clotting, vitamin K1 is converted to this epoxide form and then rapidly reduced...
| Schlagworte: | 2,3-epoxy Phylloquinone, Phylloquinone oxide, Vitamin K oxide,... |
| Anwendung: | Inactive vitamin K1 metabolite, Vitamin K epoxide reductase substrate |
| CAS | 25486-55-9 |
| MW: | 466.7 D |
ab 159,00 €
Human VKOR / Vitamin K epoxide reductase complex subunit...
Artikelnummer: G-HUFI00702.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
641,00 €
R-(+)-Warfarin
Artikelnummer: LKT-W0273.1
Optically active R enantiomer of Warfarin. S-warfarin is found to be more potent than the R-isomer in producing an anticoagulant response.
| Schlagworte: | (+)-Warfarin |
| CAS | 5543-58-8 |
| MW: | 308.33 D |
ab 162,00 €
S(-)-Warfarin Sodium
Artikelnummer: LKT-W0274.1
Optically active S enantiomer of Warfarin Sodium. Used for preventing thrombosis and embolism. A synthetic derivative of coumarin. Decreases blood coagulation by inhibiting vitamin K epoxide reductase.
| MW: | 330.31 D |
ab 202,00 €
R(+)-Warfarin Sodium
Artikelnummer: LKT-W0275.1
Optically active R enantiomer of Warfarin Sodium. Used for preventing thrombosis and embolism. A synthetic derivative of coumarin. Decreases blood coagulation by inhibiting vitamin K epoxide reductase.
| MW: | 330.31 D |
ab 162,00 €
Acenocoumarol
Artikelnummer: Cay10010569-10
Acenocoumarol is an anticoagulant and vitamin K antagonist. It inhibits the reduction of vitamin K1 epoxide to vitamin K1 by vitamin K1 epoxide reductase (VKOR) (IC50 = 1.5 and 5.8 nM for VKORC1 and VKORC1L1, respectively). Acenocoumarol also inhibits a variety of VKOR mutants in cell-based reporter assays (IC50s =...
| Schlagworte: | Acenocoumarin, G-23350, Nicoumalone, Sinthrome(R), Sintrom(R),... |
| Anwendung: | Anticoagulant, vitamin K antagonist |
| CAS | 152-72-7 |
| MW: | 353.3 D |
ab 77,00 €
(R)-Acenocoumarol
Artikelnummer: Cay9000337-1
Acenocoumarol is a short-lived oral anti-coagulant, which, like warfarin, functions by inhibiting vitamin K epoxide reductase. It has higher intrinsic anticoagulant potency than warfarin and phenprocoumon, when evaluated in vitro. Acenocoumarol has a single chiral center that gives rise to two different enantiomeric...
| Schlagworte: | (R)-Acenocoumarin, (R)-Nicoumalone, 4-hydroxy-3-[(1R)-1-(4-nitrophenyl)-3-oxobutyl]-2H-1-benzopyran-2-one |
| CAS | 66556-77-2 |
| MW: | 353.3 D |
ab 181,00 €