Zu "K05259" wurden 166 Artikel gefunden!
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Glucagon (hydrochloride)
Artikelnummer: Cay24204-1
Glucagon is a peptide hormone produced from proglucagon in pancreatic alpha cells that has a role in the regulation of glucose metabolism. Pulsatile application of glucagon to rat hepatocytes stimulates glucose production ex vivo. It also stimulates glucose output from perfused rat livers via increases in...
| Schlagworte: | glucagon (swine) |
| Ursprungsart: | swine |
| CAS | 19179-82-9 |
| MW: | 3482.8 D |
ab 134,00 €
Anti-Glucagon / GCG, clone GCG/13090R
Artikelnummer: NSJ-V5903SAF-100UG
1 mg/ml in 1X PBS, BSA free, sodium azide free. GCG antibody targets Glucagon, a 29 amino acid peptide hormone encoded by the GCG gene and primarily localized to secretory granules within pancreatic alpha cells. Glucagon is synthesized as part of the larger precursor protein Proglucagon, which undergoes...
| Schlagworte: | Anti-GCG, Anti-Pro-glucagon, Glucagon Antibody / GCG |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
810,00 €
Anti-Glucagon / GCG, clone GCG/13090R
Artikelnummer: NSJ-V5903-100UG
0.2 mg/ml in 1X PBS with 0.05% BSA, 0.05% sodium azide. GCG antibody targets Glucagon, a 29 amino acid peptide hormone encoded by the GCG gene and primarily localized to secretory granules within pancreatic alpha cells. Glucagon is synthesized as part of the larger precursor protein Proglucagon, which undergoes...
| Schlagworte: | Anti-GCG, Anti-Pro-glucagon, Glucagon Antibody / GCG |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 375,00 €
Anti-Recombinant GLP-1, clone A229
Artikelnummer: E-AN301530L.100
Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining...
| Schlagworte: | Anti-GCG, Anti-Pro-glucagon, Recombinant GLP-1 Monoclonal Antibody |
| Anwendung: | WB, IHC, IF, FCM |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat, mouse |
ab 303,00 €
Anti-Recombinant Glucagon, clone 2D12
Artikelnummer: E-AN301252L.100
The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein...
| Schlagworte: | Anti-GCG, Anti-Pro-glucagon, Recombinant Glucagon Monoclonal Antibody |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 257,00 €
GLP-1 (7-36) amide (trifluoroacetate salt)
Artikelnummer: Cay15069-1
GLP-1 (7-36) amide is a peptide hormone released from intestinal L-cells upon nutrient consumption. It binds the GLP-1 receptor (pIC50 = 8.5) in the pancreas and displays various antidiabetic effects by potentiating glucose-induced secretion of insulin from pancreatic beta-cells, increasing insulin expression,...
| Schlagworte: | Glucagon-like Peptide 1 (7-36) amide |
| Anwendung: | GLP-1 receptor ligand |
| MW: | 3297.6 D |
ab 214,00 €
GLP-1 (7-37) (human, bovine, guinea pig, mouse, rat)...
Artikelnummer: Cay24887-500
Glucagon-like peptide 1 (GLP-1) (7-37) is an endogenous incretin hormone and truncated form of GLP-1 (1-37) (Cay-24460) that is produced via cleavage of preproglucagon in the pancreas and intestine. It binds to betaTC-1 and RIN 1027-B2 cells (Kds = 3.3 and 3.5 nM, respectively) and enhances insulin secretion in...
| Schlagworte: | Glucagon-like Peptide-1 (7-37) (human, bovine, guinea pig, mouse, rat) |
| Anwendung: | Endogenous incretin hormone |
| Ursprungsart: | human, bovine, guinea pig, mouse, rat |
| MW: | 3355.7 D |
281,00 €
Tirzepatide
Artikelnummer: LKT-T342710.1
Tirzepatide is a dual GLP-1/GIP receptor co-agonist. It has been shown to stimulate catabolism of branched-chain amino acids and branched-chain keto acids in thermogenic brwon adipose tissue in mice. It has demonstrated superior glycemic control compared with GLP-1R agonism and improved insulin sensitivity. SMILES:...
| Schlagworte: | LY3298176, Mounjaro |
| Anwendung: | GLP-1/GIP receptor co-agonist |
| CAS | 2023788-19-2 |
| MW: | 4813 D |
ab 229,00 €
GLP-1 (1-32) (bullfrog) (trifluoroacetate salt)
Artikelnummer: Cay40718-5
Glucagon-like peptide 1 (GLP-1) (1-32) is an endogenous incretin hormone. It increases intracellular cAMP levels using HEK293 cells expressing human GLP-1 receptor (GLP-1R, EC50 = 0.051 nM). In vivo, GLP-1 (1-32) (30 mg/kg) reduces blood glucose levels in an oral glucose tolerance test (OGTT) in fasted mice.Formal...
| Schlagworte: | Glucagon-like Peptide 1 (1-32),... |
| Anwendung: | Endogenous incretin hormone |
| MW: | 3658.1 D |
ab 40,00 €
Semaglutide
Artikelnummer: LKT-S176481.1
Semaglutide is a long-acting GLP-1 receptor agonist. Treatment of obese mice led to reduced body weight, improved oxidative stress indexes, and improved performance in water maze testing. Pretreatment of albino mice with induced ischemia and reperfusion injury with semaglutide showed modulated inflammatory response...
| Schlagworte: | NN9535, NNC 0113-0217 |
| Anwendung: | GLP-1 agonist |
| CAS | 910463-68-2 |
| MW: | 4113.64 D |
ab 100,00 €
Anti-Glucagon, clone 329CT36.10.10
Artikelnummer: ARG56870.100
Protein function: Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating...
| Schlagworte: | Anti-GCG |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
616,00 €
Skyrin
Artikelnummer: Cay13102-1
Skyrin is a fungal metabolite characterized by a bisanthraquinone structure. It interferes with glucagon signaling through adenylate cyclase without binding to the glucagon receptor. At 10 µM, skyrin reduces both glucagon-stimulated cAMP production and glycogenolysis. It does not interfere with epinephrine or...
| Schlagworte: | Endothianin, Rhodophyscin, 2,2',4,4',5,5'-hexahydroxy-7,7'-dimethyl-[1S,1'-bianthracene]-9,9',10,10'-tetrone |
| Anwendung: | Antioxidant, glucagon antagonist |
| CAS | 602-06-2 |
| MW: | 538.5 D |
390,00 €