Zu "K05259" wurden 153 Artikel gefunden!

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Glucagon (hydrochloride)
Glucagon (hydrochloride)

Artikelnummer: Cay24204-1

Glucagon is a peptide hormone produced from proglucagon in pancreatic alpha cells that has a role in the regulation of glucose metabolism. Pulsatile application of glucagon to rat hepatocytes stimulates glucose production ex vivo. It also stimulates glucose output from perfused rat livers via increases in...
Schlagworte: glucagon (swine)
Ursprungsart: swine
CAS 19179-82-9
MW: 3482.8 D
ab 130,00 €
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Anti-Recombinant GLP-1, clone A229
Anti-Recombinant GLP-1, clone A229

Artikelnummer: E-AN301530L.100

Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining...
Schlagworte: Anti-GCG, Anti-Pro-glucagon, Recombinant GLP-1 Monoclonal Antibody
Anwendung: WB, IHC, IF, FCM
Wirt: Rabbit
Spezies-Reaktivität: human, rat, mouse
ab 304,00 €
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Anti-Recombinant Glucagon, clone 2D12
Anti-Recombinant Glucagon, clone 2D12

Artikelnummer: E-AN301252L.100

The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein...
Schlagworte: Anti-GCG, Anti-Pro-glucagon, Recombinant Glucagon Monoclonal Antibody
Anwendung: IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
ab 258,00 €
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GLP-1 (7-36) amide (trifluoroacetate salt)
GLP-1 (7-36) amide (trifluoroacetate salt)

Artikelnummer: Cay15069-1

GLP-1 (7-36) amide is a peptide hormone released from intestinal L-cells upon nutrient consumption. It binds the GLP-1 receptor (pIC50 = 8.5) in the pancreas and displays various antidiabetic effects by potentiating glucose-induced secretion of insulin from pancreatic beta-cells, increasing insulin expression,...
Schlagworte: Glucagon-like Peptide 1 (7-36) amide
Anwendung: GLP-1 receptor ligand
MW: 3297.6 D
ab 207,00 €
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GLP-1 (7-37) (human, bovine, guinea pig, mouse, rat) (trifluoroacetate salt)
GLP-1 (7-37) (human, bovine, guinea pig, mouse, rat)...

Artikelnummer: Cay24887-500

Glucagon-like peptide 1 (GLP-1) (7-37) is an endogenous incretin hormone and truncated form of GLP-1 (1-37) (Cay-24460) that is produced via cleavage of preproglucagon in the pancreas and intestine. It binds to betaTC-1 and RIN 1027-B2 cells (Kds = 3.3 and 3.5 nM, respectively) and enhances insulin secretion in...
Schlagworte: Glucagon-like Peptide-1 (7-37) (human, bovine, guinea pig, mouse, rat)
Anwendung: Endogenous incretin hormone
Ursprungsart: human, bovine, guinea pig, mouse, rat
MW: 3355.7 D
273,00 €
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Tirzepatide
Tirzepatide

Artikelnummer: LKT-T342710.1

Tirzepatide is a dual GLP-1/GIP receptor co-agonist. It has been shown to stimulate catabolism of branched-chain amino acids and branched-chain keto acids in thermogenic brwon adipose tissue in mice. It has demonstrated superior glycemic control compared with GLP-1R agonism and improved insulin sensitivity. SMILES:...
Schlagworte: LY3298176, Mounjaro
Anwendung: GLP-1/GIP receptor co-agonist
CAS 2023788-19-2
MW: 4813 D
ab 229,00 €
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GLP-1 (1-32) (bullfrog) (trifluoroacetate salt)
GLP-1 (1-32) (bullfrog) (trifluoroacetate salt)

Artikelnummer: Cay40718-5

Glucagon-like peptide 1 (GLP-1) (1-32) is an endogenous incretin hormone. It increases intracellular cAMP levels using HEK293 cells expressing human GLP-1 receptor (GLP-1R, EC50 = 0.051 nM). In vivo, GLP-1 (1-32) (30 mg/kg) reduces blood glucose levels in an oral glucose tolerance test (OGTT) in fasted mice.Formal...
Schlagworte: Glucagon-like Peptide 1 (1-32),...
Anwendung: Endogenous incretin hormone
MW: 3658.1 D
ab 38,00 €
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Semaglutide
Semaglutide

Artikelnummer: LKT-S176481.1

Semaglutide is a long-acting GLP-1 receptor agonist. Treatment of obese mice led to reduced body weight, improved oxidative stress indexes, and improved performance in water maze testing. Pretreatment of albino mice with induced ischemia and reperfusion injury with semaglutide showed modulated inflammatory response...
Schlagworte: NN9535, NNC 0113-0217
Anwendung: GLP-1 agonist
CAS 910463-68-2
MW: 4113.64 D
ab 100,00 €
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Anti-Glucagon, clone 329CT36.10.10
Anti-Glucagon, clone 329CT36.10.10

Artikelnummer: ARG56870.100

Protein function: Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating...
Schlagworte: Anti-GCG
Anwendung: WB
Wirt: Mouse
Spezies-Reaktivität: human
616,00 €
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Skyrin
Skyrin

Artikelnummer: Cay13102-1

Skyrin is a fungal metabolite characterized by a bisanthraquinone structure. It interferes with glucagon signaling through adenylate cyclase without binding to the glucagon receptor. At 10 µM, skyrin reduces both glucagon-stimulated cAMP production and glycogenolysis. It does not interfere with epinephrine or...
Schlagworte: Endothianin, Rhodophyscin, 2,2',4,4',5,5'-hexahydroxy-7,7'-dimethyl-[1S,1'-bianthracene]-9,9',10,10'-tetrone
Anwendung: Antioxidant, glucagon antagonist
CAS 602-06-2
MW: 538.5 D
378,00 €
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Chicken Glucagon ELISA Kit
Chicken Glucagon ELISA Kit

Artikelnummer: G-CHFI00021.96

ELISA Type: Sandwich. Detection Range: 1.563-100µg/mL. Sensitivity: 0.938µg/mL. Sample Types: Serum, Plasma. Protein function: [Glucagon]: Plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. [The UniProt Consortium]
Schlagworte: GCG
Anwendung: Sandwich ELISA
Spezies-Reaktivität: chicken
698,00 €
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Anti-Glucagon, clone K79bB10
Anti-Glucagon, clone K79bB10

Artikelnummer: NSJ-R30040

0.5mg/ml with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1XPBS.
Schlagworte: Anti-GCG, Glucagon Antibody
Anwendung: IHC (paraffin), IF
Wirt: Mouse
Spezies-Reaktivität: human, mouse, rat, rabbit
790,00 €
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