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Zu "K05215" wurden 14 Artikel gefunden!
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Artikelnummer: Cay13324-5
NF449 is an analog of suramin that selectively inhibits P2X1 purinergic receptors (pIC50 = 6.3) with a potency 19-fold greater than at P2X3, P2Y1, P2Y2, or P2Y11. Through selective inhibition of the P2X1 receptor, 10 mg/kg NF449 has been used to decrease intravascular platelet aggregation in a mouse model of...
Schlagworte: | 4,4',4'',4'''-[carbonylbis[imino-5,1,3-benzenetriylbis(carbonylimino)]]tetrakis-1,3-benzenedisulfonic acid, octasodium salt |
Anwendung: | Suramin analog, P2X1 inhibitor |
CAS | 627034-85-9 |
MW: | 1505.1 D |
ab 50,00 €
Artikelnummer: Cay10008956-5
alpha,beta-Methyleneadenosine 5'-triphosphate (alphabeta-methylene ATP) is a phosphonic analog of ATP that is characterized by the replacement of the bridging oxygen atom between the alpha- and beta-phosphate groups with methylene. It is an agonist of P2X purinoceptors P2X1 and P2X3 (EC50 = ~1 µM) and is ~1,000-fold...
Schlagworte: | alphabeta-methylene ATP, 5'-[hydrogen P-[[hydroxy(phosphonooxy)phosphinyl]methyl]phosphonate] adenosine, trisodium salt |
Anwendung: | P2X1 / P2X3 agonist |
CAS | 1343364-54-4 |
MW: | 571.2 D |
ab 84,00 €
Artikelnummer: Cay20902-5
TNP-ATP is a derivative of ATP and an antagonist at the purinergic receptor subtypes P2X1, P2X3, and P2X2/3 (IC50s = 6, 0.9, and 7 nM, respectively). It is selective for those receptor subtypes over P2X2, P2X4, and P2X7 receptors (IC50s = 2,000, 15,200, and >30,000 nM, respectively). TNP-ATP inhibits calcium flux in...
Schlagworte: | ((3a'R,4'R,6'R,6a'R)-4'-(6-amino-9H-purin-9-yl)-6'-(((((((hydroxyoxidophosphoryl)oxy)oxidophosphoryl)oxy)oxidophosphoryl)o... |
Anwendung: | P2X receptor antagonist, nucleotide binding site probe |
MW: | 1123 D |
600,00 €
Artikelnummer: Cay17234-1
NF 023 is a purinergic P2X1 receptor antagonist (IC50 = 0.21 µM). It is selective for P2X1 over P2X2-4 receptors (IC50s = >50, 28.9 and >100 µM, respectively). It inhibits alpha,beta-methylene ATP-induced vasoconstriction in isolated rabbit saphenous arteries (pA2 = 5.69). NF 023 also inhibits hepatitis C virus...
Schlagworte: | 8,8'-[carbonylbis(imino-3,1-phenylenecarbonylimino)]bis-1,3,5-naphthalenetrisulfonic acid, hexasodium salt |
Anwendung: | P2X1 receptor antagonist, HCV NS3 helicase inhibitor |
CAS | 104869-31-0 |
MW: | 1162.9 D |
ab 48,00 €
-10 %
Rabattaktion
Artikelnummer: ELK-ES9967.100
The protein encoded by this gene belongs to the P2X family of G-protein-coupled receptors. These proteins can form homo-and heterotimers and function as ATP-gated ion channels and mediate rapid and selective permeability to cations. This protein is primarily localized to smooth muscle where binds ATP and mediates...
Schlagworte: | Anti-P2X1, Anti-P2RX1, Anti-ATP receptor, Anti-P2X purinoceptor 1, Anti-Purinergic receptor, P2RX1 rabbit pAb |
Anwendung: | WB, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
169,00 €
ab 152,10 €
Artikelnummer: VHPS-6565
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Schlagworte: | P2X1, P2RX1, ATP receptor, P2X purinoceptor 1, Purinergic receptor |
Anwendung: | RNA quantification |
43,00 €
Artikelnummer: VMPS-4493
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Schlagworte: | P2X1, P2rx1, ATP receptor, P2X purinoceptor 1, Purinergic receptor |
Anwendung: | RNA quantification |
43,00 €
Artikelnummer: VRPS-4268
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Schlagworte: | P2X1, P2rx1, ATP receptor, RP-2 protein, P2X purinoceptor 1, Purinergic receptor |
Anwendung: | RNA quantification |
52,00 €
Artikelnummer: 039575-APC.200
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic...
Schlagworte: | Anti-P2X1, Anti-P2RX1, Anti-ATP receptor, Anti-P2X purinoceptor 1, Anti-Purinergic receptor |
Anwendung: | FLISA, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
993,00 €
Artikelnummer: 039575-Biotin.200
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic...
Schlagworte: | Anti-P2X1, Anti-P2RX1, Anti-ATP receptor, Anti-P2X purinoceptor 1, Anti-Purinergic receptor |
Anwendung: | ELISA, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
993,00 €
Artikelnummer: 039575-FITC.200
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic...
Schlagworte: | Anti-P2X1, Anti-P2RX1, Anti-ATP receptor, Anti-P2X purinoceptor 1, Anti-Purinergic receptor |
Anwendung: | FLISA, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
993,00 €
Artikelnummer: 039575-HRP.200
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic...
Schlagworte: | Anti-P2X1, Anti-P2RX1, Anti-ATP receptor, Anti-P2X purinoceptor 1, Anti-Purinergic receptor |
Anwendung: | ELISA, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
993,00 €