Zu "K05212" wurden 19 Artikel gefunden!
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Human GRIN2D (Glutamate Receptor, Ionotropic,...
Artikelnummer: ELK-ELK4418.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human GRIN2D. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human GRIN2D....
| Schlagworte: | EB11, NR2D, GluN2D, GRIN2D, NMDAR2D, Glutamate receptor ionotropic, NMDA 2D, N-methyl D-aspartate receptor subtype 2D,... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Memantine (hydrochloride)
Artikelnummer: Cay14184-50
Memantine is an NMDA receptor antagonist that blocks NMDA-induced currents in rat retinal ganglion cells by 90% when used at a concentration of 12 µM. It reverses inhibition of dephosphorylation of the synthetic tau phosphopeptide p17 (tau194-207) induced by the endogenous inhibitor of protein phosphatase 2A (PP2A)...
| Schlagworte: | Akatinol, Axura, Ebix, Namenda, NSC 102290, SUN Y7017, 3,5-dimethyl-tricyclo[3.3.1.13,7]decan-1-amine, monohydrochloride |
| Anwendung: | NMDA open-channel blocker |
| CAS | 41100-52-1 |
| MW: | 215.8 D |
ab 35,00 €
Anti-GRIN2D
Artikelnummer: E-AB-15809.120
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are...
| Schlagworte: | Anti-EB11, Anti-NR2D, Anti-GRIN2D, Anti-GluN2D, Anti-NMDAR2D, Anti-Glutamate receptor ionotropic, NMDA 2D, Anti-N-methyl... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 71,00 €
Flupirtine (maleate)
Artikelnummer: Cay16674-50
Flupirtine is an activator of voltage-gated potassium channel 7 (Kv7/KCNQ). It induces relaxation of preconstricted pulmonary arteries isolated from wild-type and serotonin transporter-overexpressing (SERT+) mice. Flupirtine (30 mg/kg per day) decreases mean right ventricular pressure and right ventricular...
| Schlagworte: | N-[2-amino-6-[[(4-fluorophenyl)methyl]amino]-3-pyridinyl]-carbamic acid, ethyl ester, 2Z-butenedioate |
| Anwendung: | KCNQ agonist, NMDA receptor antagonist |
| CAS | 75507-68-5 |
| MW: | 420.4 D |
ab 50,00 €
QNZ 46
Artikelnummer: Cay14857-1
QNZ 46 is an antagonist of NR2C- and NR2D-subunit containing NMDA receptors (IC50s = 6 and 3 µM, respectively, for receptors expressed in Xenopus oocytes). It is selective for NR2C- and NR2D-subunit containing NMDA receptors over receptors containing NR2A and NR2B subunits as well as over the AMPA receptor GluR1...
| Schlagworte: | 4-[6-methoxy-2-[(1E)-2-(3-nitrophenyl)ethenyl]-4-oxo-3(4H)-quinazolinyl]-benzoic acid |
| Anwendung: | NR2C/NR2D-selective NMDA receptor non-competitive antagonist |
| CAS | 1237744-13-6 |
| MW: | 443.4 D |
ab 48,00 €
CIQ
Artikelnummer: Cay17997-10
CIQ is a substituted tetrahydroisoquinoline that acts as a subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors. It is without effect at subunits NR2A, NR2B, or glutamate receptors. CIQ enhances receptor responses two-fold (EC50 = 3 µM) by increasing channel opening frequency for glutamate or...
| Schlagworte: | (3-chlorophenyl)[3,4-dihydro-6,7-dimethoxy-1-[(4-methoxyphenoxy)methyl]-2(1H)-isoquinolinyl]-methanone |
| Anwendung: | NR2C / NR2D potentiator |
| CAS | 486427-17-2 |
| MW: | 467.9 D |
ab 43,00 €
CP-392,110 (maleate)
Artikelnummer: Cay20473-1
CP-392,110 is an AMPA receptor antagonist. It inhibits AMPA receptor-mediated calcium uptake in rat cerebellar neurons (IC50 = 74 nM). CP-392,110 inhibits seizures induced by pentylenetetrazol (Cay-18682) or AMPA (Cay-14571) in mice with ID50 values of 3.8 and 3.6 mg/kg, respectively.Formal Name:...
| Schlagworte: | 3-(2-chlorophenyl)-2-[2-[6-[(diethylamino)methyl]-2-pyridinyl]ethenyl]-6-fluoro-4(3H)-quinazolinone, (2Z)-2-butenedioate |
| Anwendung: | Noncompetitive NMDA receptor NR2C/D antagonist |
| CAS | 199656-46-7 |
| MW: | 579 D |
ab 43,00 €
(-)-MK-801 (maleate)
Artikelnummer: Cay27213-5
(-)-MK-801 is an NMDA receptor antagonist (Ki = 43 nM for inhibition of spermine binding) and an isomer of (+)-MK-801 (Cay-10009019). In vivo, (-)-MK-801 blocks generalized seizures in a mouse model of epilepsy (ED50 = 0.85 mg/kg) and increases horizontal locomotor activity in mice (ED50 = 2.71 mg/kg). (-)-MK-801...
| Schlagworte: | (5R,10S)-10,11-dihydro-5-methyl-5H-dibenzo[a,d]cyclohepten-5,10-imine, (2Z)-2-butenedioate |
| Anwendung: | NMDA receptor antagonist |
| CAS | 121917-57-5 |
| MW: | 337.4 D |
ab 43,00 €
DQP1105
Artikelnummer: Cay31121-10
DQP1105 is an NMDA receptor antagonist. It selectively inhibits glutamate-induced currents in Xenopus oocytes expressing rat NR2C and NR2D subunit-containing NMDA receptors (IC50s = 8.5 and 2.7 µM, respectively) over NR2A, NR2B, NRA1, and NRK2 subunit-containing receptors (IC50s = 206, 121, 198, and 153 µM,...
| Schlagworte: | 5-(4-bromophenyl)-3-(1,2-dihydro-6-methyl-2-oxo-4-phenyl-3-quinolinyl)-4,5-dihydro-gamma-oxo-1H-pyrazole-1-butanoic acid |
| Anwendung: | NMDA receptor antagonist |
| CAS | 380560-89-4 |
| MW: | 558.4 D |
ab 60,00 €
Anti-GRIN2D
Artikelnummer: G-CAB10080.100
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 352,00 €
Anti-NMDAepsilon4
Artikelnummer: ELK-ES5662.100
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are...
| Schlagworte: | Anti-EB11, Anti-NR2D, Anti-GRIN2D, Anti-GluN2D, Anti-NMDAR2D, Anti-Glutamate receptor ionotropic, NMDA 2D, Anti-N-methyl... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat, monkey |
ab 169,00 €
Anti-GRIN2D
Artikelnummer: ELK-ES8929.100
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are...
| Schlagworte: | Anti-EB11, Anti-NR2D, Anti-GRIN2D, Anti-GluN2D, Anti-NMDAR2D, Anti-Glutamate receptor ionotropic, NMDA 2D, Anti-N-methyl... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 169,00 €