Zu "K05209" wurden 89 Artikel gefunden!
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Anti-NMDAR2A
Artikelnummer: NSJ-R30238
0.5mg/ml if reconstituted with 0.2ml sterile DI water. N-methyl-D-aspartate receptor channel, subunit epsilon-1 (NMDAR2A or NR2A) is a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and...
| Schlagworte: | Anti-GRIN2A, Anti-Glutamate receptor ionotropic, NMDA 2A, Anti-N-methyl D-aspartate receptor subtype 2A, Anti-Glutamate... |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
D-AP5
Artikelnummer: Cay14539-10
D-AP5 is a selective N-methyl-D-aspartate (NMDA) receptor antagonist (Kd = 1.4 µM) that competitively inhibits the glutamate binding site of NMDA receptors. Whereas D-AP5 is the active (-)-stereoisomer, its (+)-isomer (L-AP5) demonstrates considerably less potent NMDA receptor antagonist activity. AP5 has been...
| Schlagworte: | D-2-Amino-5-Phosphonovaleric Acid, D-APV, 5-phosphono-D-norvaline |
| Anwendung: | NMDA receptor antagonist |
| CAS | 79055-68-8 |
| MW: | 197.1 D |
ab 112,00 €
NMDA
Artikelnummer: Cay14581-50
NMDA is a synthetic amino acid derivative that acts as a specific agonist at the NMDA receptor, mimicking the excitatory action of the endogenous ligand glutamate. Signaling through the NMDA receptor influences both neuronal plasticity and neurotoxicity. Repetitive activation of NMDA synapses leads to long-term...
| Schlagworte: | N-Methyl-D-Aspartic Acid, N-methyl-D-aspartic acid |
| Anwendung: | NMDA receptor agonist |
| CAS | 6384-92-5 |
| MW: | 147.1 D |
ab 92,00 €
Memantine (hydrochloride)
Artikelnummer: Cay14184-100
Memantine is an NMDA receptor antagonist that blocks NMDA-induced currents in rat retinal ganglion cells by 90% when used at a concentration of 12 µM. It reverses inhibition of dephosphorylation of the synthetic tau phosphopeptide p17 (tau194-207) induced by the endogenous inhibitor of protein phosphatase 2A (PP2A)...
| Schlagworte: | Akatinol, Axura, Ebix, Namenda, NSC 102290, SUN Y7017, 3,5-dimethyl-tricyclo[3.3.1.13,7]decan-1-amine, monohydrochloride |
| Anwendung: | NMDA open-channel blocker |
| CAS | 41100-52-1 |
| MW: | 215.8 D |
ab 40,00 €
1-Aminocyclopropanecarboxylic Acid
Artikelnummer: Cay16132-100
1-Aminocyclopropanecarboxylic acid (ACPC) is an intermediate in the synthesis of ethylene, the plant hormone responsible for biological processes ranging from seed germination to organ senescence. ACPC has been shown to modulate NMDA receptor activity by acting as a partial agonist at the glycine-binding site on...
| Schlagworte: | ACC, ACPC, NSC 98430, 1-amino-cyclopropanecarboxylic acid |
| Anwendung: | Plant hormone precursor, NMDA receptor agonist |
| CAS | 22059-21-8 |
| MW: | 101.1 D |
ab 49,00 €
DL-AP5
Artikelnummer: Cay14540-5
DL-AP5 is the racemic version of the selective N-methyl-D-aspartate (NMDA) receptor antagonist, D-AP5 (Cay-14539). Whereas D-AP5 is the active (-)-stereoisomer that competitively inhibits the glutamate binding site of NMDA receptors (Kd = 1.4 µM), the (+)-isomer (L-AP5) demonstrates considerably less potent NMDA...
| Schlagworte: | 2-APV, DL-2-Amino-5-Phosphonovaleric acid, 5-phosphono-norvaline |
| Anwendung: | NMDA receptor antagonist |
| CAS | 76326-31-3 |
| MW: | 197.1 D |
ab 89,00 €
Anti-NMDA R2A
Artikelnummer: 612-401-D89
Anti-NMDA R2A antibody is directed against NMDA R2A protein. The antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Expect reactivity with the following species based on 100% sequence homology: bovine, canine and mouse. Protein function: NMDA receptor subtype of...
| Schlagworte: | Anti-NR2A, Anti-GluN2A, Anti-Grin2a, Anti-NMDAR2A, Anti-Glutamate receptor ionotropic, NMDA 2A, Anti-N-methyl D-aspartate... |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | rat |
877,00 €
Amantadine (hydrochloride)
Artikelnummer: Cay21364-10
Amantadine is an NMDA receptor antagonist with IC50 values of 0.93, 0.82, and 0.47 µM at -70 mV for NR1-1a/NR2A, NR1-1a/NR2B, and NR1-1a/NR2D subunit-containing recombinant receptors, respectively, expressed in HEK293 cells. It blocks the influenza A M2 proton channel (IC50 = 16 µM for the recombinant channel...
| Schlagworte: | Adamantylamine, Aminoadamantane, NSC 83653, tricyclo[3.3.1.13,7]decan-1-amine, monohydrochloride |
| Anwendung: | NMDA receptor antagonist, antiviral, M2 protein inhibitor |
| CAS | 665-66-7 |
| MW: | 187.7 D |
ab 49,00 €
Human NMDAR2A / GRIN2A ELISA Kit
Artikelnummer: G-HUFI02522.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
D-Cycloserine
Artikelnummer: Cay22194-500
D-Cycloserine is an NMDA receptor (NMDAR) partial agonist with antibiotic activity. It selectively binds to the glycine binding site (Ki = 2.33 µM) over the glutamate binding site (Ki = >100 µM). D-Cycloserine modulates memory in a T-maze footshock test in CD-1 mice with optimal memory retention at doses of 10-30...
| Schlagworte: | (+)-Cycloserine, (R)-Cycloserine, NSC 154851, NSC 76029, alpha-Cycloserine, 4R-amino-3-isoxazolidinone |
| Anwendung: | NMDAR partial agonist |
| CAS | 68-41-7 |
| MW: | 102.1 D |
ab 60,00 €
TCN 201
Artikelnummer: Cay19086-1
TCN 201 is a selective antagonist of NMDA receptors containing the NR2A subunit (pIC50s = 6.8 and 95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 15 mg/ml, DMF:PBS (pH7.2) (1:40): 0.02 mg/ml, DMSO: 20 mg/ml. lambdamax: 232 nm. SMILES:...
| Schlagworte: | 4-[[[(3-chloro-4-fluorophenyl)sulfonyl]amino]methyl]-benzoic acid 2-benzoylhydrazide |
| Anwendung: | NMDA receptor (NR2A) antagonist |
| CAS | 852918-02-6 |
| MW: | 461.9 D |
ab 60,00 €
Memantine-d6 (hydrochloride)
Artikelnummer: Cay25463-500
Memantine-d6 is intended for use as an internal standard for the quantification of memantine (Cay-14184) by GC- or LC-MS. Memantine is an NMDA receptor antagonist that blocks NMDA-induced currents in rat retinal ganglion cells by 90% when used at a concentration of 12 µM. It reverses inhibition of dephosphorylation...
| Schlagworte: | 3,5-di(methyl-d3)-tricyclo[3.3.1.13,7]decan-1-amine, monohydrochloride |
| Anwendung: | NMDA open-channel blocker, GC-MS, LC-MS, internal standard |
| CAS | 1189713-18-5 |
| MW: | 221.8 D |
ab 247,00 €