Zu "K05186" wurden 53 Artikel gefunden!
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Indiplon
Artikelnummer: Cay11638-5
Indiplon is a pyrazolopyrimidine that acts as a high-affinity positive allosteric modulator of the GABAA receptor, potentiating GABA-activated chloride currents in a dose-dependent and reversible manner. Indiplon is selective for alpha1 subunits (EC50 = 2.6 nM) as compared with alpha2, alpha3, or alpha5 (EC50 = 24,...
| Schlagworte: | NBI 34060, N-methyl-N-[3-[3-(2-thienylcarbonyl)pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-acetamide |
| Anwendung: | Allosteric GABA(A) receptor modulator |
| CAS | 325715-02-4 |
| MW: | 376.4 D |
ab 108,00 €
Picrotoxin
Artikelnummer: Cay20771-500
Picrotoxin is a natural plant-derived poison that acts as a selective GABAA receptor antagonist. It is functional in vivo and is used to study the role of GABAA receptors in the central nervous system as well in the periphery. Picrotoxin induces seizures in adult and immature animals and is used to study...
| Schlagworte: | Cocculin, NSC 403139,... |
| Anwendung: | Selective GABA-A receptor antagonist |
| CAS | 124-87-8 |
| MW: | 602.6 D |
ab 56,00 €
Anti-GABA(A) Receptor gamma 2
Artikelnummer: 612-401-C81
Anti-GABA(A) Receptor gamma 2 Antibody is directed against rat GABA(A) Receptor gamma 2. The antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Reactivity is expected fromthe following species based on 100% sequence homology: bovine chicken, canine, human, mouse non-human...
| Schlagworte: | Anti-Gabrg2, Anti-GABA(A) receptor subunit gamma-2, Anti-Gamma-aminobutyric acid receptor subunit gamma-2 |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | rat |
877,00 €
4'-chloro Deschloroalprazolam
Artikelnummer: Cay36057-1
4'-chloro Deschloroalprazolam (Cay-36057) is an analytical reference standard categorized as a benzodiazepine. This product is intended for research and forensic applications.Formal Name: 6-(4-chlorophenyl)-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine. CAS Number: 92262-72-1. Molecular Formula: C17H13ClN4....
| Schlagworte: | 6-(4-chlorophenyl)-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine |
| Anwendung: | Analytical reference standard, benzodiazepine, sedative-hypnotic |
| CAS | 92262-72-1 |
| MW: | 308.8 D |
ab 124,00 €
Anti-GABAA Receptor gamma 2
Artikelnummer: ARG52301.50
Protein function: Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital, these are bound...
| Schlagworte: | Anti-Gabrg2, Anti-GABA(A) receptor subunit gamma-2, Anti-Gamma-aminobutyric acid receptor subunit gamma-2 |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | rat |
873,00 €
Anti-GABRG2 (aa400-410), Internal
Artikelnummer: ARG65227.100
Protein function: Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital, these are bound...
| Schlagworte: | Anti-GABRG2, Anti-GABA(A) receptor subunit gamma-2, Anti-Gamma-aminobutyric acid receptor subunit gamma-2 |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | mouse, rat |
871,00 €
Anti-GABA(A) Receptor gamma 2
Artikelnummer: 112-401-C81
Anti-GABA(A) Receptor gamma 2 Antibody is directed against rat GABA(A) Receptor gamma 2. The antibody was prepared from monospecific neat serum. Expect reactivity with the following species based on 100% sequence homology: bovine, chicken, human, mouse, non-human primates and zebra fish. Protein function: GABA, the...
| Schlagworte: | Anti-Gabrg2, Anti-GABA(A) receptor subunit gamma-2, Anti-Gamma-aminobutyric acid receptor subunit gamma-2 |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | rat |
770,00 €
Anti-phospho-GABA(A) Receptor gamma 2 (Ser327)
Artikelnummer: 612-401-D52
Anti-GABA(A) Receptor gamma 2 pS327 Antibody is directed against rat phosphorylated GABA(A) Receptor gamma 2. The antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Immunolabeling of the GABAA band is completely blocked by ?-phosphatase treatment. This antibody is directed...
| Schlagworte: | Anti-phospho-Gabrg2, Anti-phospho-GABA(A) receptor subunit gamma-2, Anti-phospho-Gamma-aminobutyric acid receptor subunit... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | rat |
877,00 €
Anti-GABRG2
Artikelnummer: NSJ-R34865-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Gamma-aminobutyric acid (GABA) A receptor, gamma 2 Protein function: Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions...
| Schlagworte: | Anti-GABRG2, Anti-GABA(A) receptor subunit gamma-2, Anti-Gamma-aminobutyric acid receptor subunit gamma-2, GABRG2 Antibody |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, mouse, rat |
836,00 €
Anti-GABRG1
Artikelnummer: ARG58739.100
Protein function: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. [The UniProt Consortium]
| Schlagworte: | Anti-GABRG1, Anti-GABA(A) receptor subunit gamma-1, Anti-Gamma-aminobutyric acid receptor subunit gamma-1 |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
707,00 €
Anti-GABAA Receptor gamma2 Subunit
Artikelnummer: Cay29276-100
GABAA receptors are ligand-gated chloride channels that mediate the effects of the inhibitory neurotransmitter GABA in the CNS. They are postsynaptic heteropentameric receptors that contain protein subunits from the following isoforms: alpha1-6, beta1-4, gamma1-3, delta, epsilon, pi, theta, and rho1-3, arranged...
| Schlagworte: | GABAA Receptor Subunit gamma2, GABRG2, gamma-Aminobutyric Acid Receptor Subunit gamma2 |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
588,00 €
FG-7142
Artikelnummer: Cay29183-100
FG-7142 is a benzodiazepine receptor ligand with anxiogenic and proconvulsant properties. It increases benzodiazepine receptor ligand binding and GABA-dependent chloride uptake in primary chick cerebral cortical neurons when used at a concentration of 1 µM. FG-7142 (5 mg/kg) decreases pinning of the other animal and...
| Schlagworte: | ZK 39106, N-methyl-9H-pyrido[3,4-b]indole-3-carboxamide |
| Anwendung: | Gamma-aminobutyric acid receptor subunit gamma-2 benzodiazepine site ligand |
| CAS | 78538-74-6 |
| MW: | 225.2 D |
ab 139,00 €