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Anti-GABAA Receptor delta
Anti-GABAA Receptor delta

Artikelnummer: ARG52299.50

Protein function: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. [The UniProt Consortium]
Schlagworte: Anti-Gabrd, Anti-GABA(A) receptor subunit delta, Anti-Gamma-aminobutyric acid receptor subunit delta
Anwendung: IHC (frozen), IP, WB
Reaktivität: Mouse, Rat
467,00 €
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Anti-GABA-A receptor-delta, clone S151-3
Anti-GABA-A receptor-delta, clone S151-3

Artikelnummer: 200-301-F33

Anti-GABA-A receptor delta Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with GABA-A receptor delta from mouse and rat based on 100% homology with the immunizing sequence. No cross-reactivity against GABA-A-R-Beta 2 or -Beta3. Cross-reactivity with GABA-A...
Schlagworte: Anti-Gabrd, Anti-GABA(A) receptor subunit delta, Anti-Gamma-aminobutyric acid receptor subunit delta
Anwendung: IHC, IF, WB
Reaktivität: Rat, Mouse
493,00 €
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Bretazenil
Bretazenil

Artikelnummer: Cay28411-25

Bretazenil is a positive allosteric modulator of GABAA receptors with anticonvulsant and anxiolytic activity. It potentiates GABA-gated chloride currents in rat cortical neurons and in HEK293 cells expressing alpha1beta1gamma2 subunit-containing GABAA receptors (EC50s = 60 and 10 nM, respectively). Bretazenil...
Schlagworte: Ro 16-6028, (13aS)-8-bromo-11,12,13,13a-tetrahydro-9-oxo-9H-imidazo[1,5-a]pyrrolo[2,1-c][1,4]benzodiazepine-1-carboxylic...
Anwendung: GABA-A receptor positive allosteric modulator
CAS 84379-13-5
MW: 418.3 D
ab 37,00 €
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Anti-GABAA Receptor delta, clone S151-3
Anti-GABAA Receptor delta, clone S151-3

Artikelnummer: ARG22235.50

Protein function: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. [The UniProt Consortium]
Schlagworte: Anti-Gabrd, Anti-GABA(A) receptor subunit delta, Anti-Gamma-aminobutyric acid receptor subunit delta
Anwendung: WB, IHC, ICC, IF
Reaktivität: Human, Mouse, Rat
439,00 €
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Anti-GABAA Receptor delta, N-terminal
Anti-GABAA Receptor delta, N-terminal

Artikelnummer: ARG52299.100

Protein function: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. [The UniProt Consortium]
Schlagworte: Anti-Gabrd, Anti-GABA(A) receptor subunit delta, Anti-Gamma-aminobutyric acid receptor subunit delta
Anwendung: IHC, WB
Reaktivität: Mouse, Rat
622,00 €
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6-(4-Methoxyphenyl)-3-pyridazinamine
6-(4-Methoxyphenyl)-3-pyridazinamine

Artikelnummer: Cay17588-5

Ionotropic GABAA receptors are ligand-gated ion channels that facilitate the passing of chloride ions across the cell membrane and promote an inhibitory influence on target neurons. These receptors are the major targets for benzodiazepines and related anxiolytic drugs. 6-(4-Methoxyphenyl)-3-pyridazinamine is an...
Schlagworte: 6-(4-methoxyphenyl)-3-pyridazinamine
Anwendung: GABAA receptor antagonist
CAS 4776-87-8
MW: 201.2 D
ab 62,00 €
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Epiallopregnanolone
Epiallopregnanolone

Artikelnummer: Cay18431-25

Neuroactive steroids (widely known as neurosteroids), including progesterone (Item No.15876) and several of its metabolites, have been shown to mediate some of their physiological effects though a modulatory site on GABAA receptors. Epiallopregnanolone is a metabolite of progesterone and a 3beta-isomer of...
Schlagworte: 3beta,21-dihydroxy-5alpha-Pregnan-20-one, 3beta,5alpha-Tetrahydrodeoxycorticosterone, 3beta,5alpha-Tetrahydroprogesterone,...
Anwendung: GABAA receptor modulator control
CAS 567-01-1
MW: 334.5 D
ab 32,00 €
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Ganaxolone
Ganaxolone

Artikelnummer: Cay20919-25

Ganaxolone is a 3beta-methylated synthetic analog of the neurosteroid allopregnanolone that allosterically enhances GABAA receptor current. At nanomolar concentrations, it can potentiate GABA-evoked currents at GABAA receptor complexes containing alpha1, alpha2, alpha3, beta2, and gamma2L subunits expressed in...
Schlagworte: CCD 1042, (3alpha,5alpha)-3-hydroxy-3-methyl-pregnan-20-one
Anwendung: Allopregnanolone analog
CAS 38398-32-2
MW: 332.5 D
ab 32,00 €
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Etifoxine
Etifoxine

Artikelnummer: Cay15999-5

Etifoxine is a positive allosteric modulator of GABAA receptors that produces anxiolytic effects by preferentially modulating GABAA receptors containing beta2 or beta3 subunits (EC50s = 7.5 µM) over those bearing a beta1 subunit (EC50 > 20 µM). It has also been identified as a ligand of the translocator protein,...
Schlagworte: Etafenoxine, HOE 36-801, Stresam, 6-chloro-N-ethyl-4-methyl-4-phenyl-4H-3, 1-benzoxazin-2-amine
Anwendung: Anxiolytic, Positive allosteric GABA(A) receptor modulator
CAS 21715-46-8
MW: 300.8 D
ab 87,00 €
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U-93631
U-93631

Artikelnummer: Cay26417-50

U-93631 is a GABAA receptor ligand. It accelerates decay of GABA-induced currents in HEK293 cells expressing rat alpha1beta2, beta2gamma2, and alpha1gamma2 subunit-containing GABAA receptors when used at a concentration of 5 µM. U-93631 inhibits radioligand binding to the picrotoxin site on alpha1beta2gamma2...
Schlagworte: 4,5-dihydro-4,4-dimethyl-imidazo[1,5-a]quinoxaline-3-carboxylic acid, 1,1-dimethylethyl ester
Anwendung: GABA(A) receptor ligand
CAS 152273-12-6
MW: 299.4 D
ab 124,00 €
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Kavain
Kavain

Artikelnummer: Cay26524-50

Kavain is a kavalactone and the major constituent of the pepper plant kava (P. methysticum) and has diverse biological activities. It is a positive allosteric modulator of alpha4beta2delta subunit-containing GABAA receptors with EC50 values of 25 and 59 µM in the presence and absence of 300 µM kavain, respectively,...
Schlagworte: Kawain, NSC 112162, (6R)-5,6-dihydro-4-methoxy-6-[(1E)-2-phenylethenyl]-2H-pyran-2-one
Anwendung: Bioactive kavalactone, Alpha4beta2delta GABA(A) receptor PAM (positive allosteric modulator)
CAS 500-64-1
MW: 230.3 D
ab 32,00 €
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Anti-GABRD
Anti-GABRD

Artikelnummer: G-CAB16016.100

WB 1:500 - 1:2000. Protein function: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. [The UniProt Consortium]
Schlagworte: Anti-GABRD, Anti-GABA(A) receptor subunit delta, Anti-Gamma-aminobutyric acid receptor subunit delta, GABRD Polyclonal...
Anwendung: WB
Reaktivität: Human, Mouse, Rat
314,00 € 282,60 €
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