Zu "K05175" wurden 98 Artikel gefunden!

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Flumazenil
Flumazenil

Artikelnummer: Cay14252-10

Flumazenil is an imidazobenzodiazepine derivative that competitively inhibits benzodiazepine binding to GABAA receptors with an IC50 value of 2 nM. Flumazenil is non-selective for alpha1, alpha2, alpha3, or alpha5 subunit-containing GABAA receptors and antagonizes the actions of benzodiazepines on the central...
Schlagworte: Anexate, Lanexat, Mazicon, Ro 15-1788, Ro 1722, Ro 41-8157, Romazicon,...
Anwendung: Benzodiazepine inhibitor, Metabolic studies
CAS 78755-81-4
MW: 303.3 D
ab 38,00 €
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Anti-GABAA Receptor alpha4 Subunit
Anti-GABAA Receptor alpha4 Subunit

Artikelnummer: Cay29270-100

GABAA receptors are ligand-gated chloride channels that mediate the effects of the inhibitory neurotransmitter GABA in the CNS. They are postsynaptic heteropentameric receptors that contains protein subunits from the following isoforms: alpha1-6, beta1-4, gamma1-3, delta, epsilon, pi, theta, and rho1-3, arranged...
Schlagworte: Anti-Gabra4, Anti-GABA(A) receptor subunit alpha-4, Anti-Gamma-aminobutyric acid receptor subunit alpha-4
Anwendung: IHC, WB
Reaktivität: Mouse, Rat
499,00 €
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Anti-GABAA Receptor alpha3 Subunit (N-Term)
Anti-GABAA Receptor alpha3 Subunit (N-Term)

Artikelnummer: Cay29269-100

GABAA receptors are ligand-gated chloride channels that mediate the effects of the inhibitory neurotransmitter GABA in the CNS. They are postsynaptic heteropentameric receptors that contain protein subunits from the following isoforms: alpha1-6, beta1-4, gamma1-3, delta, epsilon, pi, theta, and rho1-3, arranged...
Schlagworte: Anti-Gabra3, Anti-Gabra-3, Anti-GABA(A) receptor subunit alpha-3, Anti-Gamma-aminobutyric acid receptor subunit alpha-3
Anwendung: WB
407,00 €
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Anti-GABAA Receptor alpha6 Subunit
Anti-GABAA Receptor alpha6 Subunit

Artikelnummer: Cay29272-100

GABAA receptors are ligand-gated chloride channels that mediate the effects of the inhibitory neurotransmitter GABA in the CNS. They are postsynaptic heteropentameric receptors that contains protein subunits from the following isoforms: alpha1-6, beta1-4, gamma1-3, delta, epsilon, pi, theta, and rho1-3, arranged...
Schlagworte: Anti-Gabra6, Anti-Gabra-6, Anti-GABA(A) receptor subunit alpha-6, Anti-Gamma-aminobutyric acid receptor subunit alpha-6
499,00 €
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Anti-GABAA Receptor alpha1 Subunit
Anti-GABAA Receptor alpha1 Subunit

Artikelnummer: Cay29266-100

GABAA receptors are ligand-gated chloride channels that mediate the effects of the inhibitory neurotransmitter GABA in the CNS. They are postsynaptic heteropentameric receptors that contain protein subunits from the following isoforms: alpha1-6, beta1-4, gamma1-3, delta, epsilon, pi, theta, and rho1-3, arranged...
Schlagworte: Anti-Gabra1, Anti-Gabra-1, Anti-GABA(A) receptor subunit alpha-1, Anti-Gamma-aminobutyric acid receptor subunit alpha-1
Anwendung: WB, IHC
Reaktivität: Mouse, Rat
407,00 €
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Anti-GABAA Receptor alpha1 Subunit (N-Term)
Anti-GABAA Receptor alpha1 Subunit (N-Term)

Artikelnummer: Cay29267-100

GABAA receptors are ligand-gated chloride channels that mediate the effects of the inhibitory neurotransmitter GABA in the CNS. They are postsynaptic heteropentameric receptors that contain protein subunits from the following isoforms: alpha1-6, beta1-4, gamma1-3, delta, epsilon, pi, theta, and rho1-3, arranged...
Schlagworte: Anti-Gabra1, Anti-Gabra-1, Anti-GABA(A) receptor subunit alpha-1, Anti-Gamma-aminobutyric acid receptor subunit alpha-1
Anwendung: WB, IHC
Reaktivität: Mouse, Rat
475,00 €
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Anti-GABAA Receptor alpha5 Subunit
Anti-GABAA Receptor alpha5 Subunit

Artikelnummer: Cay29271-100

GABAA receptors are ligand-gated chloride channels that mediate the effects of the inhibitory neurotransmitter GABA in the CNS. They are postsynaptic heteropentameric receptors that contain protein subunits from the following isoforms: alpha1-6, beta1-4, gamma1-3, delta, epsilon, pi, theta, and rho1-3, arranged...
Schlagworte: Anti-Gabra5, Anti-Gabra-5, Anti-GABA(A) receptor subunit alpha-5, Anti-Gamma-aminobutyric acid receptor subunit alpha-5
Anwendung: WB, IHC
Reaktivität: Mouse, Rat
475,00 €
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L-655,708
L-655,708

Artikelnummer: Cay30322-10

L-655,708 is a ligand for alpha5 subunit-containing GABAA receptors that has nootropic activity. It selectively binds to alpha5 subunit-containing GABAA receptors over alpha1, alpha2, or alpha3 subunit-containing receptors (Kis = 1, 70, 48, and 31 nM, respectively, for recombinant human receptors). L-655,708 (10 nM)...
Schlagworte: (13aS)-11,12,13,13a-tetrahydro-7-methoxy-9-oxo-9H-imidazo[1,5-a]pyrrolo[2,1-c][1,4]benzodiazepine-1-carboxylic acid, ethyl...
Anwendung: Nootropic GABA(A) receptor subunit alpha-5 ligand
CAS 130477-52-0
MW: 341.4 D
ab 107,00 €
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Avermectin B1a
Avermectin B1a

Artikelnummer: Cay22000-5

Avermectin B1a is a macrocyclic lactone disaccharide anthelmintic agent that binds to high and low affinity sites on the mammalian GABAA receptor. Binding to the high affinity site activates the receptor to increase chloride influx, while binding to the low affinity site blocks the channel. Avermectin B1a inhibits...
Schlagworte: Antibiotic C 076B1a, L-676,863, 5-O-demethyl-avermectin A1a
Anwendung: Anthelmintic agent
CAS 65195-55-3
MW: 873.1 D
ab 62,00 €
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Etifoxine-13C-d3
Etifoxine-13C-d3

Artikelnummer: Cay30235-1

Etifoxine-13C-d3 is intended for use as an internal standard for the quantification of etifoxine (Cay-15999) by GC- or LC-MS. Etifoxine is a positive allosteric modulator of alpha1beta2gamma2 and alpha1beta3gamma2 subunit-containing GABAA receptors. It selectively increases GABA-induced currents in X. laevis oocytes...
Schlagworte: 6-chloro-N-ethyl-4-methyl-13C-d3-4-phenyl-4H-3, 1-benzoxazin-2-amine
Anwendung: GC-MS, LC-MS, Internal standard, Positive allosteric GABA(A) receptor modulator
MW: 304.8 D
ab 162,00 €
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THDOC
THDOC

Artikelnummer: Cay28364-1

THDOC is a neurosteroid and positive allosteric modulator of GABAA receptors. It inhibits binding of the convulsant t-butylbicyclophosphorothionate (TBPS) and increases binding of the benzodiazepine flunitrazepam to rat synaptosomal membrane preparations in a concentration-dependent manner. THDOC potentiates...
Schlagworte: 3alpha,5alpha-Tetrahydrodeoxycorticosterone, 3alpha,5alpha-THDOC, 5alpha,3alpha-THDOC, NSC 113927,...
Anwendung: Neurosteroid, GABA(A) receptor positive allosteric modulator
CAS 567-02-2
MW: 334.5 D
ab 42,00 €
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Anti-GABAA Receptor alpha 1
Anti-GABAA Receptor alpha 1

Artikelnummer: ARG52286.50

Protein function: Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain (PubMed:2540033, PubMed:1977069, PubMed:1376242). Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to...
Schlagworte: Anti-Gabra1, Anti-Gabra-1, Anti-GABA(A) receptor subunit alpha-1, Anti-Gamma-aminobutyric acid receptor subunit alpha-1
Anwendung: WB
Reaktivität: Mouse, Rat
467,00 €
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