Zu "K05117" wurden 101 Artikel gefunden!
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NEU
Anti-MERTK (mouse) Rabbit (Clone RM469)
Artikelnummer: Cay42835-100
MERTK is a TAM family receptor tyrosine kinase with roles in macrophage activation, apoptotic cell engulfment, and platelet aggregation. It is composed of an extracellular domain, which contains two immunoglobulin-like (Ig-like) domains and two FNIII domains, and an intracellular tyrosine kinase domain. MERTK is...
| Schlagworte: | c-Mer, MER, Proto-oncogene c-Mer, Receptor Tyrosine Kinase MerTK, RP38, Tyrosine-protein Kinase Mer |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse |
512,00 €
UNC2025
Artikelnummer: TGM-T7007-100mg
Description: UNC2025 (mrx-6313)(IC50 of 0.74 nM and 0.8 nM) is a potent and orally bioavailable dual MER/FLT3 inhibitor. UNC-2025 is about 20-fold selectivity higher than Axl and Tyro3. Target: TAM Receptor, FLT. Smiles: CCCCNc1ncc2c(cn([C@H]3CC[C@H](O)CC3)c2n1)-c1ccc(CN2CCN(C)CC2)cc1. References: Zhang W, et al. J...
| Schlagworte: | mrx-6313, UNC 2025, UNC-2025 |
| Anwendung: | Mer/FLT3 dual inhibitor |
| CAS | 1429881-91-3 |
| MW: | 476.66 D |
ab 34,00 €
ONO-7475
Artikelnummer: TGM-T8327-100mg
Description: ONO-7475 is an inhibitor with high specificity for anexelekto and MER tyrosine kinase. Target: Trk receptor, TAM Receptor. Smiles: COc1cc2nccc(Oc3ccc(NC(=O)c4cc5C(=O)CCCc5n(-c5ccccc5)c4=O)nc3)c2cc1OC. References: Ruvolo PP, et al. Anexelekto/MER tyrosine kinase inhibitor ONO-7475 arrests growth and...
| Anwendung: | Axl / Mer inhibitor |
| CAS | 1646839-59-9 |
| MW: | 562.57 D |
ab 57,00 €
MERTK/Mer Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPK-00417-100ug
Description: MER tyrosine kinase (MERTK) encodes a surface receptor localized at the apical membrane of the retinal pigment epithelium. It plays a critical role in photoreceptor outer segment internalization prior to phagocytosis. Mutations in MERTK have been associated with severe autosomal recessive retinal...
| Schlagworte: | MGC133349, Tyro12, RP38, c-Eyk, MERTK, c-mer, MER |
| MW: | 53.73 kD |
ab 417,00 €
MERTK/Mer Protein, Human, Recombinant (mFc)
Artikelnummer: TGM-TMPK-00418-100ug
Description: MER tyrosine kinase (MERTK) encodes a surface receptor localized at the apical membrane of the retinal pigment epithelium. It plays a critical role in photoreceptor outer segment internalization prior to phagocytosis. Mutations in MERTK have been associated with severe autosomal recessive retinal...
| Schlagworte: | MERTK, c-Eyk, MGC133349, RP38, c-mer, MER, Tyro12 |
| MW: | 78.9 kD |
ab 417,00 €
MERTK/Mer Protein, Mouse, Recombinant (His)
Artikelnummer: TGM-TMPK-01022-100ug
Description: MER tyrosine kinase (MERTK) encodes a surface receptor localized at the apical membrane of the retinal pigment epithelium. It plays a critical role in photoreceptor outer segment internalization prior to phagocytosis. Mutations in MERTK have been associated with severe autosomal recessive retinal...
| Schlagworte: | c-mer, RP38, MERTK, MER, MGC133349, c-Eyk, Tyro12 |
| MW: | 53.38 kD |
ab 417,00 €
Mer Protein, Human, Recombinant (His & hFc)
Artikelnummer: TGM-TMPY-00882-100ug
Description: Mer Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 80 kDa and the accession number is Q12866.
| Schlagworte: | c-Eyk, RP38, c-mer, Tyro12, MER proto-oncogene, tyrosine kinase, MER |
| MW: | 80 kD |
ab 253,00 €
Mer Protein, Mouse, Recombinant (hFc)
Artikelnummer: TGM-TMPY-02291-100ug
Description: Mer Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 79.3 kDa and the accession number is Q60805.
| Schlagworte: | Eyk, MER proto-oncogene, tyrosine kinase, Nyk, Mer, nmf12 |
| MW: | 79.3 kD |
397,00 €
Mer Protein, Human, Recombinant (aa 578-872)
Artikelnummer: TGM-TMPY-04747-50ug
Description: Mer Protein, Human, Recombinant (aa 578-872) is expressed in Baculovirus insect cells. The predicted molecular weight is 34.1 kDa and the accession number is Q12866.
| Schlagworte: | MER, RP38, MER proto-oncogene, tyrosine kinase, c-mer, Tyro12, c-Eyk |
| MW: | 34.1 kD |
497,00 €
Mer Protein, Human, Recombinant
Artikelnummer: TGM-TMPY-04330-100ug
Description: Mer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 54 kDa and the accession number is Q12866.
| Schlagworte: | Tyro12, c-Eyk, MER, RP38, MER proto-oncogene, tyrosine kinase, c-mer |
| MW: | 54 kD |
ab 450,00 €
Mer Protein, Human, Recombinant (His & GST)
Artikelnummer: TGM-TMPY-04363-50ug
Description: Mer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 62 kDa and the accession number is Q12866.
| Schlagworte: | MER proto-oncogene, tyrosine kinase, c-Eyk, RP38, c-mer, Tyro12, MER |
| MW: | 62 kD |
497,00 €
Mer Protein, Mouse, Recombinant (His & GST)
Artikelnummer: TGM-TMPY-04437-50ug
Description: Mer Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 61.7 kDa and the accession number is Q60805.
| Schlagworte: | MER proto-oncogene, tyrosine kinase, Mer, Eyk, nmf12, Nyk |
| MW: | 61.7 kD |
497,00 €