Zu "K05115" wurden 172 Artikel gefunden!
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Axl Extracellular Domain (human, recombinant)
Artikelnummer: Cay44185-100
Axl is a receptor tyrosine kinase and member of the TAM kinase family. It is composed of two immunoglobulin-like (Ig-like) domains, two fibronectin-like III domains, an extracellular cleavage site, a transmembrane region, and a C-terminal kinase domain. It is ubiquitously expressed and localizes to the cell...
| Schlagworte: | UFO |
| Anwendung: | Active protein |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
200,00 €
Anti-Recombinant Axl, clone 5A10
Artikelnummer: E-AN300623L.100
The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the...
| Schlagworte: | Anti-AXL, Anti-AXL oncogene, Anti-Tyrosine-protein kinase receptor UFO, Recombinant Axl Monoclonal Antibody |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 258,00 €
Mouse AXL ELISA Kit
Artikelnummer: ARG81697.96
Protein function: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding growth factor GAS6 and which is thus regulating many physiological processes including cell survival, cell proliferation, migration and differentiation. Ligand binding at the cell surface...
| Schlagworte: | Ark, Axl, EC=2.7.10.1, Adhesion-related kinase, Tyrosine-protein kinase receptor UFO |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
1.118,00 €
Human AXL ELISA Kit
Artikelnummer: ARG81696.96
Protein function: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding growth factor GAS6 and which is thus regulating many physiological processes including cell survival, cell proliferation, migration and differentiation. Ligand binding at the cell surface...
| Schlagworte: | UFO, AXL, EC=2.7.10.1, AXL oncogene, Tyrosine-protein kinase receptor UFO |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
1.118,00 €
AXL, His, Human
Artikelnummer: GSC-Z05046-100
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell...
| Schlagworte: | AXL, AXL oncogene, Tyrosine-protein kinase receptor UFO |
| Ursprungsart: | human |
| MW: | 45.4 kD |
ab 228,00 €
![AXL[Biotin], His & Avi, Human](https://www.biomol.com/media/image/67/94/c3/GSC-Z04404-100_200x200.png "AXL[Biotin], His & Avi, Human")
AXL[Biotin], His & Avi, Human
Artikelnummer: GSC-Z04404-100
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell...
| Schlagworte: | AXL, AXL oncogene, Tyrosine-protein kinase receptor UFO |
| Ursprungsart: | human |
| MW: | 48.7 kD |
ab 887,00 €
AXL hFc Chimera, Human
Artikelnummer: GSC-Z05047-100
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell...
| Schlagworte: | AXL, AXL oncogene, Tyrosine-protein kinase receptor UFO |
| Ursprungsart: | human |
| MW: | 72.6 kD |
ab 457,00 €
AXL, His & Avi, Human
Artikelnummer: GSC-Z05048-100
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell...
| Schlagworte: | AXL, AXL oncogene, Tyrosine-protein kinase receptor UFO |
| Ursprungsart: | human |
| MW: | 48.7 kD |
ab 228,00 €
![Axl hFc Chimera[Biotin], Human](https://www.biomol.com/media/image/35/57/51/GSC-Z04405-100_200x200.png "Axl hFc Chimera[Biotin], Human")
Axl hFc Chimera[Biotin], Human
Artikelnummer: GSC-Z04405-100
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell...
| Schlagworte: | AXL, AXL oncogene, Tyrosine-protein kinase receptor UFO |
| Ursprungsart: | human |
| MW: | 72.6 kD |
ab 887,00 €
AXL, His, Mouse
Artikelnummer: GSC-Z06018-100
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell...
| Schlagworte: | Axl, Adhesion-related kinase, Tyrosine-protein kinase receptor UFO |
| Ursprungsart: | mouse |
| MW: | 47.8 kD |
ab 228,00 €
R428
Artikelnummer: Cay21523-1
R428 is a small molecule inhibitor of Axl kinase, both in an in vitro biochemical assay and in a cell-based assay using phosphorylation of Ser473 on Akt as the readout (EC50s = 14 nM for both). It is orally bioavailable, blocks angiogenesis in corneal micropocket and tumor models, and reduces metastatic burden while...
| Schlagworte: | Bemcentinib, BGB 324,... |
| Anwendung: | Axl kinase inhibitor |
| CAS | 1037624-75-1 |
| MW: | 506.6 D |
ab 38,00 €
Gilteritinib
Artikelnummer: Cay21503-1
Gilteritinib is an inhibitor of FMS-related tyrosine kinase 3 (FLT3, IC50 = 5 nM for the wild-type enzyme). It inhibits mutant forms of FLT3, including FLT3 with the internal tandem duplication mutation (FLT3-ITD), FLT3-ITD expressing the F691L mutation, and FLT3 with various tyrosine kinase domain mutations...
| Schlagworte: | ASP2215,... |
| Anwendung: | FLT3 / AXL inhibitor |
| CAS | 1254053-43-4 |
| MW: | 552.7 D |
ab 49,00 €