Zu "K05113" wurden 45 Artikel gefunden!
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NVP-BHG712
Artikelnummer: Cay18489-5
The EphB4 receptor tyrosine kinase (cloned from erythropoietin-producing hepatocellular carcinoma) and its ligand ephrinB2 play an important role in embryonic vessel development and vascular remodeling. Signaling from this pair is also involved in tumor angiogenesis. NVP-BHG712 is an orally bioavailable inhibitor of...
| Schlagworte: | 4-methyl-3-[[1-methyl-6-(3-pyridinyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino]-N-[3-(trifluoromethyl)phenyl]-benzamide |
| Anwendung: | EphB4 kinase autophosphorylation inhibitor |
| CAS | 940310-85-0 |
| MW: | 503.5 D |
ab 50,00 €
XL647
Artikelnummer: Cay27049-1
XL647 is a multi-kinase inhibitor (IC50s = 0.3, 16, 1.5, 8.7, and 1.4 nM for EGFR, ErbB2, KDR, FLT4, and EphB4, respectively). It is selective for these kinases over a panel of 10 tyrosine kinases and 55 serine/threonine kinases at 10 µM. XL647 inhibits growth of A431 cells expressing wild-type EGFR and H1975...
| Schlagworte: | EXEL-7647, Tesevatinib,... |
| Anwendung: | Multi-kinase (EGFR, ErbB2, KDR, FLT4, EphB4) inhibitor |
| CAS | 781613-23-8 |
| MW: | 491.4 D |
ab 130,00 €
Anti-EphB4
Artikelnummer: ARG57429.100
Protein function: Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling...
| Schlagworte: | Anti-HTK, Anti-EPHB4, EC=2.7.10.1, Anti-Ephrin type-B receptor 4, Anti-Hepatoma transmembrane kinase,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse |
624,00 €
EphB4, active human recombinant protein
Artikelnummer: BPS-40201
Active human EPHB4 ( GenBank Accession No. NM_004444), (a.a. 563-987) with N-terminal His tag, MW=50 kDa, expressed in a Baculovirus infected Sf9 cell expression system. One unit is defined as the amount of enzyme that will transfer 1 nmol phosphate to tyrosine substrate per minute at pH 7.4 and 30° C. Assay buffer:...
| Schlagworte: | HTK, EPHB4, EC=2.7.10.1, Ephrin type-B receptor 4, Hepatoma transmembrane kinase, Tyrosine-protein kinase TYRO11, |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 50 kD |
525,00 €
Mouse Ephb4 / Ephrin type-B receptor 4 ELISA Kit
Artikelnummer: G-MOFI00452.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
694,00 €
Anti-EPHB4
Artikelnummer: E-AB-62074.120
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and...
| Schlagworte: | Anti-HTK, Anti-EPHB4, EC=2.7.10.1, Anti-Ephrin type-B receptor 4, Anti-Hepatoma transmembrane kinase,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 198,00 €
EPHB4 Kinase Assay Kit
Artikelnummer: BPS-78009
The EPHB4 Kinase Assay Kit is designed to measure EPHB4 kinase activity for screening and profiling applications using ADP-Glo(R) Kinase Assay as a detection reagent.
| Schlagworte: | Ephrin type-B receptor 4 kit, |
| Anwendung: | Enzyme kinetics, drug discovery, HTS |
| Spezies-Reaktivität: | human |
789,00 €
Anti-EPHB4
Artikelnummer: G-CAB3293.50
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 352,00 €
JI-101
Artikelnummer: Cay36405-25
JI-101 is an inhibitor of VEGFR2, PDGFRbeta, and Eph tyrosine kinase receptor 4 (EphB4) with anticancer activity.Formal Name: N-[1-[(2-amino-4-pyridinyl)methyl]-1H-indol-4-yl]-N'-(5-bromo-2-methoxyphenyl)-urea. CAS Number: 900573-88-8. Synonyms: CGI1842. Molecular Formula: C22H20BrN5O2. Formula Weight: 466.3....
| Schlagworte: | CGI1842, N-[1-[(2-amino-4-pyridinyl)methyl]-1H-indol-4-yl]-N'-(5-bromo-2-methoxyphenyl)-urea |
| Anwendung: | VEGFR2 inhibitor |
| CAS | 900573-88-8 |
| MW: | 466.3 D |
ab 39,00 €
Anti-EPHB4 / EPH Receptor B4, clone EPHB4/6391
Artikelnummer: NSJ-V5210-100UG
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date. While the biological activities of these receptors have yet to be determined, there is increasing evidence that they are involved in central...
| Schlagworte: | Anti-HTK, Anti-EPHB4, EC=2.7.10.1, Anti-Ephrin type-B receptor 4, Anti-Hepatoma transmembrane kinase,... |
| Anwendung: | IHC (paraffin) |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 332,00 €
Anti-EPHB4 / EPH Receptor B4, clone EPHB4/6391
Artikelnummer: NSJ-V5210SAF-100UG
1 mg/ml in 1X PBS, BSA free, sodium azide free. The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date. While the biological activities of these receptors have yet to be determined, there is increasing evidence that they are involved in central nervous system function...
| Schlagworte: | Anti-HTK, Anti-EPHB4, EC=2.7.10.1, Anti-Ephrin type-B receptor 4, Anti-Hepatoma transmembrane kinase,... |
| Anwendung: | IHC (paraffin) |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
752,00 €
Anti-EPHB4 / EPH Receptor B4, clone EPHB4/6392
Artikelnummer: NSJ-V5211-100UG
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date. While the biological activities of these receptors have yet to be determined, there is increasing evidence that they are involved in central...
| Schlagworte: | Anti-HTK, Anti-EPHB4, EC=2.7.10.1, Anti-Ephrin type-B receptor 4, Anti-Hepatoma transmembrane kinase,... |
| Anwendung: | IHC (paraffin) |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 332,00 €