Zu "K05101" wurden 76 Artikel gefunden!
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Anti-TrkCT1
Artikelnummer: 600-401-993
Protein function: Receptor for neurotrophin-3 (NT-3). This is a tyrosine- protein kinase receptor. Known substrates for the Trk receptors are SHC1, PI 3-kinase, and PLC-gamma-1. [The UniProt Consortium]
| Schlagworte: | Anti-TrkC, Anti-Ntrk3, Anti-Trk-C, Anti-GP145-TrkC, EC=2.7.10.1, Anti-TrkC tyrosine kinase, Anti-NT-3 growth factor... |
| Anwendung: | ELISA, IP, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse |
733,00 €
LOXO-195
Artikelnummer: Cay27062-1
LOXO-195 is an inhibitor of the receptor tyrosine kinases TrkA and TrkC (IC50s = 0.6 and G595R, TrkAG667C, TrkCG623R, and TrkCG696A (IC50s = 2, 9.8, 2.3, and 50 value of 1.9 nM. It selectively inhibits proliferation of Trk fusion-positive K12, CUTO-3, and MO-91 cell lines (IC50s = =5 nM) over Trk fusion-negative...
| Schlagworte: | Selitrectinib,... |
| Anwendung: | TrkA / TrkC inhibitor |
| CAS | 2097002-61-2 |
| MW: | 380.4 D |
ab 38,00 €
TRKC, active human recombinant protein, GST-tag
Artikelnummer: BPS-40282
Human TRKC, also known as NTKR3 (Neurotrophic Tyrosine Kinase Receptor, type 3) or NT-3 Receptor, GenBank Accession No. NM_002530, amino acids 456-825(end), with N-terminal GST-tag, MW=68kDa, expressed in Sf9 cells via a baculovirus expression system.
| Schlagworte: | TRKC, Trk-C, NTRK3, GP145-TrkC, EC=2.7.10.1, TrkC tyrosine kinase, NT-3 growth factor receptor, Neurotrophic tyrosine... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | Baculovirus |
| Ursprungsart: | human |
| MW: | 68 kD |
536,00 €
Human TrkC/NTRK3 ELISA Kit
Artikelnummer: G-HUFI02675.96
ELISA Type: Sandwich. Detection Range: 0.156-10µg/mL. Sensitivity: 0.094µg/mL. Sample Types: Serum, Plasma. Protein function: Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling...
| Schlagworte: | TRKC, NTRK3, Trk-C, GP145-TrkC, EC=2.7.10.1, TrkC tyrosine kinase, NT-3 growth factor receptor, Neurotrophic tyrosine... |
| Anwendung: | Sandwich ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Anti-TrkC
Artikelnummer: NSJ-R31098
0.5mg/ml if reconstituted with 0.2ml sterile DI water. NTRK3(Neurotrophic Tyrosine Kinase Receptor Type 3), also known as TRKC, is a protein that in humans is encoded by the NTRK3 gene. By PCR analysis of a somatic cell hybrid panel and by fluorescence in situ hybridization with the cDNA clone, McGregor et al.(1994)...
| Schlagworte: | Anti-TRKC, Anti-Trk-C, Anti-NTRK3, Anti-GP145-TrkC, EC=2.7.10.1, Anti-TrkC tyrosine kinase, Anti-NT-3 growth factor... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-TrkC
Artikelnummer: NSJ-R31099
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Neurotrophic Tyrosine Kinase Receptor Type 3, also known as TRKC, is a protein that in humans is encoded by the NTRK3 gene. TrkC is preferentially expressed in the brain, in situ hybridization studies showed transcripts in the hippocampus, cerebral cortex, and...
| Schlagworte: | Anti-TRKC, Anti-Trk-C, Anti-NTRK3, Anti-GP145-TrkC, EC=2.7.10.1, Anti-TrkC tyrosine kinase, Anti-NT-3 growth factor... |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-TrkC
Artikelnummer: NSJ-F50685-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Receptor for neurotrophin-3 (NT-3). This is a tyrosine-protein kinase receptor. Known substrates for the trk receptors are SHC1, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties. [UniProt] Protein function: Receptor tyrosine kinase...
| Schlagworte: | Anti-TRKC, Anti-Trk-C, Anti-NTRK3, Anti-GP145-TrkC, EC=2.7.10.1, Anti-TrkC tyrosine kinase, Anti-NT-3 growth factor... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Anti-TrkC
Artikelnummer: NSJ-F50686-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. TRKC, a member of the insuline receptor subfamily of Tyr protein kinases, is a receptor for neurotrophin-3 (NT-3). Known substrates for the TRK receptors are SHC, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties. The protein is...
| Schlagworte: | Anti-TRKC, Anti-Trk-C, Anti-NTRK3, Anti-GP145-TrkC, EC=2.7.10.1, Anti-TrkC tyrosine kinase, Anti-NT-3 growth factor... |
| Anwendung: | IHC, WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Anti-TrkC
Artikelnummer: ARG40506.50
Protein function: Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival...
| Schlagworte: | Anti-TRKC, Anti-Trk-C, Anti-NTRK3, Anti-GP145-TrkC, EC=2.7.10.1, Anti-TrkC tyrosine kinase, Anti-NT-3 growth factor... |
| Anwendung: | IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
551,00 €
LOXO-101
Artikelnummer: Cay27056-25
LOXO-101 is an inhibitor of the tropomyosin-related kinases TrkA, TrkB, and TrkC (IC50s = 2-20 nM). It is selective for TrkA, -B, and -C over a panel of 226 kinases at 1 µM. LOXO-101 inhibits the growth of CUTO-3.29, KM12, and MO-91 patient-derived cancer cell lines (IC50s = In vivo, LOXO-101 (60 and 200 mg/kg)...
| Schlagworte: | ARRY-470, Larotrectinib,... |
| Anwendung: | TrkA / TrkB / TrkC inhibitor |
| CAS | 1223403-58-4 |
| MW: | 428.4 D |
ab 67,00 €
LOXO-195
Artikelnummer: LKT-L589938.1
| Schlagworte: | LOXO195, 0J45910S3X, Selitrectinib,... |
| Anwendung: | TrkA / TrkC inhibitor |
| CAS | 2097002-61-2 |
| MW: | 380.43 D |
ab 123,00 €
Belizatinib
Artikelnummer: Cay28458-5
Belizatinib is an inhibitor of anaplastic lymphoma kinase (ALK) and tropomyosin-related kinases A/B/C (IC50s = 0.7 and 98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml. lambdamax: 324 nm. SMILES:...
| Schlagworte: | TSR-011,... |
| Anwendung: | ALK inhibitor, TrkA/TrkB/TrkC inhibitor |
| CAS | 1357920-84-3 |
| MW: | 577.7 D |
ab 56,00 €