Zu "K05098" wurden 358 Artikel gefunden!
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Human VEGFR2/KDR ELISA Kit
Artikelnummer: SCC-EK0544
Vascular endothelial growth factor receptor 2 (VEGFR-2), also known as kinase insert domain receptor (KDR, a type III receptor tyrosine kinase), is a VEGF receptor. Through in situ hybridization using genomic DNA as a probe for metaphase chromosomes, VEGFR2 was localized to 4q11-->q12. VEGFR2 and the adherens...
| Schlagworte: | hVEGFR-ELISA, KDR, Fetal liver kinase 1, Kinase insert domain receptor, Protein-tyrosine kinase receptor flk-1, Vascular... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
701,00 €
Anti-Human VEGF Receptor 2 Antibody Pair
Artikelnummer: ABS-ES-1967.1
Product Description: Kinase insert domain receptor (KDR), also known as vascular endothelial growth factor receptor 2 (VEGFR-2) or CD309, is a type IV receptor tyrosine kinase encoded by the KDR gene in humans and plays a central role in mediating the effects of vascular endothelial growth factor (VEGF) on...
| Schlagworte: | Anti-KDR, Anti-Fetal liver kinase 1, Anti-Kinase insert domain receptor, Anti-Protein-tyrosine kinase receptor flk-1,... |
| Anwendung: | ELISA |
| Wirt: | Mouse/Mouse |
| Spezies-Reaktivität: | human |
1.080,00 €
Anti-Human VEGF Receptor 2 Antibody Pair
Artikelnummer: ABS-ES-1966.1
Product Description: Kinase insert domain receptor (KDR), also known as vascular endothelial growth factor receptor 2 (VEGFR-2) or CD309, is a type IV receptor tyrosine kinase encoded by the KDR gene in humans and plays a central role in mediating the effects of vascular endothelial growth factor (VEGF) on...
| Schlagworte: | Anti-KDR, Anti-Fetal liver kinase 1, Anti-Kinase insert domain receptor, Anti-Protein-tyrosine kinase receptor flk-1,... |
| Anwendung: | ELISA |
| Wirt: | Mouse/Mouse |
| Spezies-Reaktivität: | human |
1.080,00 €
Anti-Human VEGF Receptor 2 Antibody Pair
Artikelnummer: ABS-ES-1965.1
Product Description: Kinase insert domain receptor (KDR), also known as vascular endothelial growth factor receptor 2 (VEGFR-2) or CD309, is a type IV receptor tyrosine kinase encoded by the KDR gene in humans and plays a central role in mediating the effects of vascular endothelial growth factor (VEGF) on...
| Schlagworte: | Anti-KDR, Anti-Fetal liver kinase 1, Anti-Kinase insert domain receptor, Anti-Protein-tyrosine kinase receptor flk-1,... |
| Anwendung: | ELISA |
| Wirt: | Mouse/Mouse |
| Spezies-Reaktivität: | human |
1.080,00 €
VEGFR2 Kinase Inhibitor IV
Artikelnummer: Cay45474-1
VEGFR2 kinase inhibitor IV is an inhibitor of VEGFR2 (IC50 = 19 nM). It is greater than 100-fold selective for VEGFR2 over FGFR1 and Src but only 1.8-, 10-, and 10-fold selective over PDGFRbeta, FLT1, and FLT2, respectively. VEGFR2 kinase inhibitor IV inhibits mitogenesis in human umbilical vein endothelial cells...
| Schlagworte: | Vascular Endothelial Growth Factor Receptor 2 Kinase Inhibitor IV,... |
| Anwendung: | VEGFR2 inhibitor |
| CAS | 216661-57-3 |
| MW: | 307.37 D |
ab 278,00 €
VEGFR2/KDR Protein, Mouse, Recombinant (aa 192-761, hFc)
Artikelnummer: TGM-TMPS-00146-10ug
Description: VEGFR2/KDR Protein, Mouse, Recombinant (aa 192-761, hFc) is expressed in HEK293 Cells. The accession number is P35918.
| Schlagworte: | VEGFR , VEGFR2 , CD309 , KDR , FLK1 |
| MW: | 153.5 kD |
ab 34,00 €
Human VEGFR2 ELISA Kit
Artikelnummer: ARG81425.96
Protein function: Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of...
| Schlagworte: | KDR, FLK1, CD309, FLK-1, VEGFR-2, EC=2.7.10.1, Fetal liver kinase 1, Kinase insert domain receptor, Protein-tyrosine... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
1.118,00 €
Sorafenib
Artikelnummer: LKT-S5868.25
c-Raf, Ret, VEGFR2 inhibitor, potential STAT3/5 inhibitor, potential HMT inhibitor.
| Schlagworte: | 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide |
| Anwendung: | BRAF / FLT3 / PDGFRB / VEGFR2 / VEGFR3 / c-KIT inhibitor |
| CAS | 284461-73-0 |
| MW: | 464.82 D |
ab 109,00 €
VEGFR2(KDR) Kinase Assay Kit
Artikelnummer: BPS-40325
Vascular endothelial growth factor receptor 2 (VEGFR2), also called Kinase insert Domain receptor (KDR), is a tyrosine kinase (TK) receptor for VEGFs that plays a central role in tumor angiogenesis, therefore the inhibition of VEGFR2 is a promising therapeutic strategy for inhibiting angiogenesis and tumor growth....
| Schlagworte: | KDR, Kinase Insert Domain Receptor, VEGFR2, Vascular Endothelial Growth Factor Receptor 2, CD309, FLK-1, Fetal Liver... |
| Anwendung: | Enzyme kinetics, drug discovery, HTS |
| Spezies-Reaktivität: | human |
842,00 €
GW-806742X
Artikelnummer: SYN-1215-M001
Soluble in DMSO. Potent protein kinase VEGFR2 inhibitor (2nm range). Binds to the pseudokinase domain of MLKL and blocks cell death by necroptosis, as well. With regards to its role in necroptosis, it is an ATP-mimetic that was shown to bind recombinant mouse MLKL pseudokinase domain, which showed inhibited...
| Schlagworte: | GW806742X, AC1NS7PT, AGN-PC-0LQ49Y |
| Anwendung: | VEGFR2 inhibitor |
| CAS | 579515-63-2 |
| MW: | 573,6 D |
ab 139,00 €
XL184
Artikelnummer: Cay18464-1
XL184 is an inhibitor of VEGFR2 (IC50 = 0.035 nM). It is selective for VEGFR2 over Ron, EGFR, IGF-1R, and EphA4/B4, but also inhibits c-Met, RET, c-Kit, Axl, FLT3, and Tie2 (IC50s = 1.3, 5.2, 4.6, 7, 11.3, and 14.3 nM, respectively). XL184 (4.6 nM) inhibits VEGF-induced tubule formation in human microvascular...
| Schlagworte: | BMS-907351, Cabozantinib, N'-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide |
| Anwendung: | Pan tyrosine kinase inhibitor |
| CAS | 849217-68-1 |
| MW: | 501.5 D |
ab 69,00 €
Apatinib
Artikelnummer: Cay21268-5
Apatinib is a tyrosine kinase inhibitor that potently suppresses the kinase activity of vascular endothelial growth factor 2 (VEGFR2, IC50 = 1 nM). It is less effective against c-kit (IC50 = 429 nM), Ret (IC50 = 13 nM), and c-src (IC50 = 53 nM) and does not inhibit EGFR, Her-2, or FGFR1 (IC50s = >10 µM). Apatinib...
| Schlagworte: | YN968D1, N-[4-(1-cyanocyclopentyl)phenyl]-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide |
| Anwendung: | VEGFR2 inhibitor |
| CAS | 811803-05-1 |
| MW: | 397.5 D |
ab 144,00 €