Zu "K05096" wurden 134 Artikel gefunden!
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Mouse VEGFR1 (Vascular Endothelial Growth Factor Receptor...
Artikelnummer: ELK-ELK1078.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse VEGFR1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse VEGFR1....
| Schlagworte: | Flt1, Emrk2, FLT-1, VEGFR-1, EC=2.7.10.1, Fms-like tyrosine kinase 1, Embryonic receptor kinase 2, Tyrosine-protein kinase... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 303,00 €
Human VEGFR1 (Vascular Endothelial Growth Factor Receptor...
Artikelnummer: ELK-ELK1126.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human VEGFR1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human VEGFR1....
| Schlagworte: | FLT, FLT1, FLT-1, VEGFR-1, EC=2.7.10.1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 303,00 €
Anti-FLT1 (Icrucumab Biosimilar Antibody)
Artikelnummer: G-HDBS0116.100
Protein function: Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. Acts as a...
| Schlagworte: | Anti-FLT, Anti-FLT1, Anti-FLT-1, Anti-VEGFR-1, EC=2.7.10.1, Anti-Fms-like tyrosine kinase 1, Anti-Tyrosine-protein kinase... |
| Anwendung: | ELISA, FC |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
399,00 €
Pazopanib
Artikelnummer: Cay12097-10
Pazopanib is a multi-kinase inhibitor that inhibits the VEGF receptors VEGFR1, VEGFR2, and VEGFR3 (IC50s = 10, 30, and 47 nM, respectively, in a cell-free enzyme assay). It also inhibits PDGFRalpha, PDGFRbeta, and c-Kit (IC50s = 71, 84, and 74 nM, respectively, in a cell-free enzyme assay) as well as additional...
| Schlagworte: | GSK-VEG10003, GW786034B, 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide |
| Anwendung: | Broad spectrum tyrosine kinase inhibitor |
| CAS | 444731-52-6 |
| MW: | 437.5 D |
ab 37,00 €
Regorafenib
Artikelnummer: Cay18498-5
Regorafenib is an orally bioavailable multi-kinase inhibitor with anticancer activity. It inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRbeta with IC50 values of 1.5, 2.5, 4.2, 7, 13, and 22 nM, respectively. Regorafenib also inhibits B-RAF, VEGFR3, FGFR, and Tie2 (IC50s = 28, 46, 202, and 311 nM, respectivey)...
| Schlagworte: | BAY 73-4506,... |
| Anwendung: | VEGFR inhibitor |
| CAS | 755037-03-7 |
| MW: | 482.8 D |
ab 60,00 €
BIBF 1120
Artikelnummer: Cay11022-10
BIBF 1120 is an inhibitor of the receptor tyrosine kinases VEGFR, FGFR, and PDGFR (IC50s = 13-34, 37-610, 59, and 65 nM for VEGFR1-3, FGFR1-4, PDGFRalpha, and PDGFRbeta, respectively). It is selective for VEGFR, FGFR, and PDGFR over a panel of 33 kinases but does inhibit FLT3, LCK, LYN, and Src (IC50s = 16-156 nM)....
| Schlagworte: | Nintedanib,... |
| Anwendung: | Receptor tyrosine kinase inhibitor |
| CAS | 656247-17-5 |
| MW: | 539.6 D |
ab 60,00 €
Vatalanib (hydrochloride)
Artikelnummer: Cay14868-10
Vatalanib is an antagonist of the VEGF receptors, inhibiting the receptor tyrosine kinase activities of VEGFR1 (Flt1), VEGFR2 (KDR), and VEGFR3 (Flt4) with IC50 values of 77, 37, and 190 nM, respectively. It less potently inhibits PDGF and c-Kit (IC50 = 600 and 700 nM) and has no effect on a large panel of...
| Schlagworte: | CGP 79787, PTK/ZK, PTK787, N-(4-chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine, dihydrochloride |
| Anwendung: | VEGFR inhibitor |
| CAS | 212141-51-0 |
| MW: | 419.7 D |
ab 69,00 €
Nintedanib, Ethanesulfonate Salt
Artikelnummer: LC-N-9055_2g
Solubility: Soluble in DMSO at 25 mg/mL with warming, soluble in ethanol at 8 mg/mL with warming, soluble in water at 25 mg/mL with warming, buffers, serum, or other additives may increase or decrease the aqueous solubility. This research compound is the ethanesulfonate salt form of nintedanib. Nintedanib is an...
| Schlagworte: | BIBF1120 Esylate, Intedanib Esylate, Nintedanib Esylate |
| Anwendung: | Antifibrosis, Tyrosine kinase inhibitor |
| CAS | 656247-18-6 |
| MW: | 649.76 D |
ab 82,00 €
Nintedanib, Free Base
Artikelnummer: LC-N-9077_25mg
Solubility: Soluble in DMSO at 25 mg/mL with warming, very poorly soluble in ethanol, very poorly soluble in water, maximum solubility in plain water is estimated to be about 10-20 µM, buffers, serum, or other additives may increase or decrease the aqueous solubility. This product was previously Cat. No. I-9077,...
| Schlagworte: | BIBF1120, Intedanib, Vargatef |
| Anwendung: | Antifibrosis, Tyrosine kinase inhibitor |
| CAS | 656247-17-5 |
| MW: | 539.62 D |
ab 82,00 €
Lenvatinib
Artikelnummer: Cay19375-10
Lenvatinib is an inhibitor of the receptor tyrosine kinases VEGF receptor 2 (VEGFR2) and VEGFR3 (IC50s = 4 and 5.2 nM, respectively). It also inhibits the related kinases VEGFR1, FGFR1, PDGFRalpha, PDGFRbeta and Kit (IC50s = 22, 46, 51, 39, and 100 nM, respectively). Lenvatinib (30 mg/kg, twice per day) reduces...
| Schlagworte: | E-7080, ER-203492-00, 4-[3-chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-7-methoxy-6-quinolinecarboxamide |
| Anwendung: | VEGFR / FGFR / PDGFR inhibitor |
| CAS | 417716-92-8 |
| MW: | 426.9 D |
ab 43,00 €
ZM 306416
Artikelnummer: Cay16968-10
ZM 306416 is an inhibitor of vascular endothelial growth factor (VEGF) receptor tyrosine kinase that antagonizes the activity of KDR and Flt VEGF receptors with IC50 values of 100 nM and 2 µM, respectively. It has also been reported to inhibit EGFR kinase with an IC50 value of 98%. Formulation: (Request formulation...
| Schlagworte: | CB-676475, N-(4-chloro-2-fluorophenyl)-6,7-dimethoxy-4-quinazolinamine |
| Anwendung: | VEGFR inhibitor |
| CAS | 690206-97-4 |
| MW: | 333.7 D |
ab 60,00 €
Pazopanib, Free Base (GW-786034, Armala, Votrient, CAS...
Artikelnummer: LC-P-6706_100mg
Soluble in DMSO at 8.3 mg/mL with slight warming, very poorly soluble in ethanol, very poorly soluble in water, maximum solubility in plain water is estimated to be about 10-20 µM, buffers, serum, or other additives may increase or decrease the aqueous solubility
| Schlagworte: | GSK-VEG10003, GW786034B, Votrient,... |
| Anwendung: | Broad spectrum tyrosine kinase inhibitor |
| CAS | 444731-52-6 |
| MW: | 437,52 D |
ab 91,00 €