Zu "K05096" wurden 186 Artikel gefunden!
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Anti-Recombinant VEGF Receptor 1, clone 1A8
Artikelnummer: E-AN301010L.100
FLT1(fms related tyrosine kinase 1) Homo sapiens This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane...
| Schlagworte: | Anti-FLT1, Anti-Fms-like tyrosine kinase 1, Anti-Tyrosine-protein kinase FRT, Anti-Tyrosine-protein kinase receptor FLT,... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 258,00 €
Human sFLT-1 / sVEGFR1 ELISA Kit
Artikelnummer: ARG81424.96
Protein function: Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. May play an...
| Schlagworte: | FLT, FLT1, FLT-1, VEGFR-1, EC=2.7.10.1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
1.085,00 €
Mouse FLT1 / VEGFR1 ELISA Kit
Artikelnummer: ARG81689.96
Protein function: Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. May play an...
| Schlagworte: | Flt1, Emrk2, FLT-1, VEGFR-1, EC=2.7.10.1, Fms-like tyrosine kinase 1, Embryonic receptor kinase 2, Tyrosine-protein kinase... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
1.118,00 €
BIBF 1120
Artikelnummer: Cay11022-10
BIBF 1120 is an inhibitor of the receptor tyrosine kinases VEGFR, FGFR, and PDGFR (IC50s = 13-34, 37-610, 59, and 65 nM for VEGFR1-3, FGFR1-4, PDGFRalpha, and PDGFRbeta, respectively). It is selective for VEGFR, FGFR, and PDGFR over a panel of 33 kinases but does inhibit FLT3, LCK, LYN, and Src (IC50s = 16-156 nM)....
| Schlagworte: | Nintedanib,... |
| Anwendung: | Receptor tyrosine kinase inhibitor |
| CAS | 656247-17-5 |
| MW: | 539.6 D |
ab 53,00 €
Regorafenib
Artikelnummer: Cay18498-5
Regorafenib is an orally bioavailable multi-kinase inhibitor with anticancer activity. It inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRbeta with IC50 values of 1.5, 2.5, 4.2, 7, 13, and 22 nM, respectively. Regorafenib also inhibits B-RAF, VEGFR3, FGFR, and Tie2 (IC50s = 28, 46, 202, and 311 nM, respectivey)...
| Schlagworte: | BAY 73-4506,... |
| Anwendung: | VEGFR inhibitor |
| CAS | 755037-03-7 |
| MW: | 482.8 D |
ab 67,00 €
Pazopanib
Artikelnummer: Cay12097-10
Pazopanib is a multi-kinase inhibitor that inhibits the VEGF receptors VEGFR1, VEGFR2, and VEGFR3 (IC50s = 10, 30, and 47 nM, respectively, in a cell-free enzyme assay). It also inhibits PDGFRalpha, PDGFRbeta, and c-Kit (IC50s = 71, 84, and 74 nM, respectively, in a cell-free enzyme assay) as well as additional...
| Schlagworte: | GSK-VEG10003, GW786034B, 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide |
| Anwendung: | Broad spectrum tyrosine kinase inhibitor |
| CAS | 444731-52-6 |
| MW: | 437.5 D |
ab 44,00 €
Vatalanib (hydrochloride)
Artikelnummer: Cay14868-10
Vatalanib is an antagonist of the VEGF receptors, inhibiting the receptor tyrosine kinase activities of VEGFR1 (Flt1), VEGFR2 (KDR), and VEGFR3 (Flt4) with IC50 values of 77, 37, and 190 nM, respectively. It less potently inhibits PDGF and c-Kit (IC50 = 600 and 700 nM) and has no effect on a large panel of...
| Schlagworte: | CGP 79787, PTK/ZK, PTK787, N-(4-chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine, dihydrochloride |
| Anwendung: | VEGFR inhibitor |
| CAS | 212141-51-0 |
| MW: | 419.7 D |
ab 77,00 €
Anti-FLT1, recombinant clone 6F6
Artikelnummer: CSB-RA008732MA1HU.100
Protein function: Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. Acts as a...
| Schlagworte: | Anti-FLT, Anti-FLT1, Anti-FLT-1, Anti-VEGFR-1, EC=2.7.10.1, Anti-Fms-like tyrosine kinase 1, Anti-Tyrosine-protein kinase... |
| Anwendung: | ELISA, IHC |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
ab 206,00 €
Lenvatinib
Artikelnummer: Cay19375-10
Lenvatinib is an inhibitor of the receptor tyrosine kinases VEGF receptor 2 (VEGFR2) and VEGFR3 (IC50s = 4 and 5.2 nM, respectively). It also inhibits the related kinases VEGFR1, FGFR1, PDGFRalpha, PDGFRbeta and Kit (IC50s = 22, 46, 51, 39, and 100 nM, respectively). Lenvatinib (30 mg/kg, twice per day) reduces...
| Schlagworte: | E-7080, ER-203492-00, 4-[3-chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-7-methoxy-6-quinolinecarboxamide |
| Anwendung: | VEGFR / FGFR / PDGFR inhibitor |
| CAS | 417716-92-8 |
| MW: | 426.9 D |
ab 49,00 €
BIBF 1202
Artikelnummer: Cay27176-10
BIBF 1202 is an active metabolite of the VEGFR, FGFR, and PDGFR inhibitor BIBF 1120 (nintedanib, Cay-11022). It is formed from BIBF 1120 by intracellular esterases. BIBF 1202 inhibits VEGFR2 with an IC50 value of 62 nM.Formal Name:...
| Schlagworte: | (3Z)-2,3-dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-1H-indole-6-car... |
| Anwendung: | Active metabolite, receptor tyrosine kinase inhibitor |
| CAS | 894783-71-2 |
| MW: | 525.6 D |
ab 60,00 €
Tivozanib
Artikelnummer: LKT-T3585.10
An oral VEGF receptor tyrosine kinase inhibitor.
| Schlagworte: | AV-951 |
| CAS | 475108-18-0 |
| MW: | 454.86 D |
ab 212,00 €
ZM 306416
Artikelnummer: Cay16968-10
ZM 306416 is an inhibitor of vascular endothelial growth factor (VEGF) receptor tyrosine kinase that antagonizes the activity of KDR and Flt VEGF receptors with IC50 values of 100 nM and 2 µM, respectively. It has also been reported to inhibit EGFR kinase with an IC50 value of 98%. Formulation: (Request formulation...
| Schlagworte: | CB-676475, N-(4-chloro-2-fluorophenyl)-6,7-dimethoxy-4-quinazolinamine |
| Anwendung: | VEGFR inhibitor |
| CAS | 690206-97-4 |
| MW: | 333.7 D |
ab 67,00 €