Zu "K05095" wurden 148 Artikel gefunden!
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Rat FGFR4 (Fibroblast Growth Factor Receptor 4) ELISA Kit
Artikelnummer: ELK-ELK0439.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat FGFR4. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat FGFR4. Next,...
| Schlagworte: | CD334, Fgfr4, FGFR-4, EC=2.7.10.1, Fibroblast growth factor receptor 4 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
ab 352,00 €
Human FGFR4 (Fibroblast Growth Factor Receptor 4) ELISA Kit
Artikelnummer: ELK-ELK3161.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human FGFR4. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human FGFR4. Next,...
| Schlagworte: | JTK2, CD334, FGFR4, FGFR-4, EC=2.7.10.1, Fibroblast growth factor receptor 4 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
FGFR4, Active human recombinant protein, N-terminal GST tag
Artikelnummer: BPS-40213
Human FGFR4, (GenBank Accession No. NM_002011) with N-terminal GST tag, MW= 65 kDa, expressed in Sf9 cells via a baculovirus expression system
| Schlagworte: | JTK2, FGFR4, CD334, FGFR-4, EC=2.7.10.1, Fibroblast growth factor receptor 4, |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | Insect cells |
| Ursprungsart: | human |
| MW: | 65 kD |
555,00 €
PD 173074
Artikelnummer: Cay13032-5
The fibroblast growth factor receptors (FGFRs) are cell surface receptors with intrinsic tyrosine kinase activity, which is necessary for receptor activation and signal propagation. PD 173074 is a potent and selective inhibitor of FGFR tyrosine kinase activity, blocking autophosphorylation of FGFR1 with an IC50...
| Schlagworte: | N-[2-[[4-(diethylamino)butyl]amino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)-urea |
| Anwendung: | FGFR inhibitor |
| CAS | 219580-11-7 |
| MW: | 523.7 D |
ab 53,00 €
FGF401
Artikelnummer: Cay23029-5
FGF401 is an inhibitor of FGF receptor 4 (FGFR4, IC50 = 1.9 nM). It inhibits proliferation of Huh7 carcinoma cells with an IC50 value of 12 nM. FGF401 induces bile acid synthesis in dogs, increasing plasma and fecal levels of bile acids when administered at a dose of 45 mg/kg per day for four weeks. It also...
| Schlagworte: | Roblitinib,... |
| Anwendung: | FGFR4 inhibitor |
| CAS | 1708971-55-4 |
| MW: | 506.6 D |
ab 52,00 €
BLU-9931
Artikelnummer: Cay18405-1
Fibroblast growth factor receptor 4 (FGFR4) is the receptor for fibroblast growth factor 19 (FGF19), which is a tightly controlled hormone that regulates bile acid synthesis and hepatocyte proliferation in the normal liver. Aberrant signaling through the FGFR4/FGF19 signaling complex has been implicated in...
| Schlagworte: | N-[2-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-quinazolinyl]amino]-3-methylphenyl]-2-propenamide |
| Anwendung: | FGFR4 inhibitor |
| CAS | 1538604-68-0 |
| MW: | 509.4 D |
ab 66,00 €
H3B-6527
Artikelnummer: Cay26072-1
H3B-6527 is an inhibitor of FGF receptor 4 (FGFR4, IC50 = 50s = 320, 1,290, and 1,060 nM, respectively), as well as TAOK2, JNK2, and CSF1R (IC50s = 690, >10,000, and >10,000 nM, respectively). H3B-6527 increases the expression of the cytochrome P450 (CYP) isoform CYP7A1 and decreases phosphorylation of ERK1/2 in...
| Schlagworte: | N-[2-[[6-[[[(2,6-dichloro-3,5-dimethoxyphenyl)amino]carbonyl]methylamino]-4-pyrimidinyl]amino]-5-(4-ethyl-1-piperazinyl)ph... |
| Anwendung: | FGFR4 inhibitor |
| CAS | 1702259-66-2 |
| MW: | 629.5 D |
ab 109,00 €
Anti-Phospho-FGFR-4 (Tyr642)
Artikelnummer: E-AB-21090.120
The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein...
| Schlagworte: | Anti-phospho-JTK2, Anti-phospho-FGFR4, Anti-phospho-CD334, Anti-phospho-FGFR-4, EC=2.7.10.1, Anti-phospho-Fibroblast... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 71,00 €
FGFR4-IN-1
Artikelnummer: Cay21342-5
FGFR-IN-1 is an inhibitor of FGF receptor 4 (FGFR4, IC50 = 1.3 nM). It is selective for FGFR4 over FGFR1 and a panel of 36 kinases (IC50s = >10 µM for all). It inhibits proliferation of Hep3B and Huh7 hepatic cancer cells with IC50 values of 1.1 and 2.5 nM, respectively. FGFR-IN-1 reduces tumor growth by 62.7 and...
| Schlagworte: | N-[5-cyano-4-[(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(3-oxo-4-morpholinyl)methyl]-1,8-naphthyridine-1... |
| Anwendung: | FGFR-4 inhibitor |
| CAS | 1708971-72-5 |
| MW: | 493.5 D |
ab 50,00 €
Human FGFR4 / CD334 / FGF Receptor 4 ELISA Kit
Artikelnummer: G-HUFI02461.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
641,00 €
Anti-FGFR4
Artikelnummer: NSJ-R31606
0.5mg/ml if reconstituted with 0.2ml sterile DI water. FGFR4(Fibroblast growth factor receptor 4), also known as CD334, is a protein that in humans is encoded by the FGFR4 gene. It is mapped to 5q35.2. The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid...
| Schlagworte: | Anti-JTK2, Anti-FGFR4, Anti-CD334, Anti-FGFR-4, EC=2.7.10.1, Anti-Fibroblast growth factor receptor 4, FGFR4 Antibody |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
755,00 €
FIIN-3
Artikelnummer: Cay20709-1
FIIN-3 is an inhibitor of FGF receptors (FGFRs, IC50s = 13, 21, 31, and 35 nM for recombinant FGFR1-4, respectively). It is selective for FGFRs over a panel of 456 kinases at a concentration of 1 µM, however, it does inhibit EGFR (IC50 = 204 nM). FIIN-3 inhibits growth of Ba/F3 cells that are dependent on the kinase...
| Schlagworte: | N-[4-[[[[(2,6-dichloro-3,5-dimethoxyphenyl)amino]carbonyl][6-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino... |
| Anwendung: | Potent, selective, irreversible, covalent FGFR inhibitor |
| CAS | 1637735-84-2 |
| MW: | 691.6 D |
ab 50,00 €