Zu "K05091" wurden 543 Artikel gefunden!
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Anti-Recombinant c-Kit, clone A186
Artikelnummer: E-AN301491L.100
Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF...
| Schlagworte: | Anti-KIT, Anti-p145 c-kit, Anti-Proto-oncogene c-Kit, Anti-Piebald trait protein, Anti-Tyrosine-protein kinase Kit,... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 303,00 €
Anti-phospho-c-Kit (Tyr823)
Artikelnummer: NSJ-F48722-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell...
| Schlagworte: | Anti-phospho-KIT, Anti-phospho-p145 c-kit, Anti-phospho-Proto-oncogene c-Kit, Anti-phospho-Piebald trait protein,... |
| Anwendung: | DB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Anti-Zebrafish Kita / Kit / Scfr
Artikelnummer: NSJ-RZ1184
0.5mg/ml if reconstituted with 0.2ml sterile DI water. The Kit protein in zebrafish (Danio rerio), encoded by the kit gene (also referred to as kita or kitb depending on isoform), is a homolog of the mammalian c-Kit receptor, a type III receptor tyrosine kinase. Kit plays an essential role in multiple developmental...
| Schlagworte: | Anti-kita, Anti-Tyrosine-protein kinase Kit, Anti-Mast/stem cell growth factor receptor kita, Zebrafish Kita Antibody /... |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | zebrafish |
948,00 €
CD117 (c-Kit), His-Tag Recombinant
Artikelnummer: BPS-83765-1
Recombinant human CD117, also known as c-Kit, encompassing amino acids 26-520, corresponding to the extracellular domain of the protein. This construct contains a C-terminal His-tag (6xHis). The protein was affinity purified. c-KIT is a proto-oncogene and a type III transmembrane receptor for mast cell growth...
| Schlagworte: | KIT, Mast/stem cell growth factor receptor Kit, Piebald trait protein, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit,... |
| Anwendung: | Binding studies |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 150+glyc. kD |
ab 367,00 €
Briquilimab
Artikelnummer: BPS-83766-1
Briquilimab, also known as JSP-191 or AMG-191, is a humanized IgG1 monoclonal antibody that targets CD117 (or c-Kit). Briquilimab blocks the interaction between CD117 receptor and stem cell factor. c-KIT is a proto-oncogene and a type III transmembrane receptor for mast cell growth factor, also known as stem cell...
| Schlagworte: | KIT, Mast/stem cell growth factor receptor Kit, Piebald trait protein, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit,... |
| Anwendung: | ELISA, FC, FA |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
ab 656,00 €
Mouse CD117 / c-Kit ELISA Kit
Artikelnummer: ARG81971.96
Protein function: Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In...
| Schlagworte: | Sl, Kit, SCFR, CD117, EC=2.7.10.1, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit, Mast/stem cell growth factor... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
1.118,00 €
cKit (V654A), active human recombinant protein
Artikelnummer: BPS-40251
Active human Kit Kit (V654A) ( GenBank Accession No. NM_000222), (a.a. 544- 976) with N-terminal His tag, MW=53.4 kDa, expressed in an Baculovirus infected Sf9 cell expression system.
| Schlagworte: | PBT, KIT, SCFR, CD117, p145 c-kit, EC=2.7.10.1, Proto-oncogene c-Kit, Piebald trait protein, Tyrosine-protein kinase Kit,... |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 53.4 kD |
536,00 €
Anti-CD117 (human), clone 57A5, Biotin conjugated
Artikelnummer: ANC-338-030
Human CD117 (c-kit) is a transmembrane protein with receptor tyrosine kinase capacity and serves as the receptor for steel factor (SLF). CD117 is expressed on almost all hematopoietic progenitor cells and receptor/ligand interaction is crucial for development of hematopoietic stem cells.
| Schlagworte: | Anti-KIT, Anti-PBT, Anti-SCFR, Anti-CD117, EC=2.7.10.1, Anti-p145 c-kit, Anti-Proto-oncogene c-Kit, Anti-Piebald trait... |
| Anwendung: | FC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
301,00 €
BLU-285
Artikelnummer: Cay22985-1
BLU-285 is a dual inhibitor of KIT receptor and platelet-derived growth factor receptor alpha (PDGFRalpha) tyrosine kinases with activating loop mutations (IC50s = 0.27 and 0.24 nM for KITD816V and PDGFRalphaD842V, respectively). It is >150-fold selective for KITD816V and PDGFRalphaD842V over a kinase panel at a...
| Schlagworte: | Avapritinib,... |
| Anwendung: | PDGFR alpha D842V / KIT Exon 17 mutant inhibitor |
| CAS | 1703793-34-3 |
| MW: | 498.6 D |
ab 51,00 €
![Elab Bright Violet 421 Anti-Mouse CD117/c-Kit Antibody [2B8]](https://www.biomol.com/media/image/ea/4e/4e/E-AB-F1092Q2-50_200x200.jpg "Elab Bright Violet 421 Anti-Mouse CD117/c-Kit Antibody [2B8]")
Elab Bright Violet 421 Anti-Mouse CD117/c-Kit Antibody [2B8]
Artikelnummer: E-AB-F1092Q2.50
CD117 is a 145 kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells...
| Schlagworte: | Sl, Kit, SCFR, CD117, EC=2.7.10.1, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit, Mast/stem cell growth factor... |
| Anwendung: | FCM |
| Wirt: | Rat |
| Spezies-Reaktivität: | mouse |
238,00 €
![Purified Anti-Human CD117 Antibody [104D2]](https://www.biomol.com/media/image/04/b1/81/E-AB-F1150A-1_200x200.jpg "Purified Anti-Human CD117 Antibody [104D2]")
Purified Anti-Human CD117 Antibody [104D2]
Artikelnummer: E-AB-F1150A.1
This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with...
| Schlagworte: | PBT, KIT, SCFR, CD117, p145 c-kit, EC=2.7.10.1, Proto-oncogene c-Kit, Piebald trait protein, Tyrosine-protein kinase Kit,... |
| Anwendung: | FCM |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 64,00 €
AST-487
Artikelnummer: Cay19477-5
AST-487 is an inhibitor of RET (IC50 = 0.88 µM), FLT3 (Ki = 0.52 µM), KDR (IC50 = 0.17 µM), c-Abl (IC50 = 0.02 µM), and c-Kit (IC50 = 0.5 µM). It has been shown to inhibit RET autophosphorylation and activation of downstream effectors and to prevent the growth of human thyroid cancer cell lines with activating...
| Schlagworte: | NVP-AST-487,... |
| Anwendung: | Flt3 / KDR / c-Abl / c-Kit / RET inhibitor |
| CAS | 630124-46-8 |
| MW: | 529.6 D |
ab 53,00 €