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NEU
Human SCFR (Stem Cell Factor Receptor) Microsample ELISA Kit
Artikelnummer: ELK-ELK1182MS.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human SCFR. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human SCFR. Next,...
| Schlagworte: | KIT, p145 c-kit, Proto-oncogene c-Kit, Piebald trait protein, Tyrosine-protein kinase Kit, Mast/stem cell growth factor... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 311,00 €
NEU
Mouse SCFR (Stem Cell Factor Receptor) Microsample ELISA Kit
Artikelnummer: ELK-ELK2525MS.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse SCFR. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse SCFR. Next,...
| Schlagworte: | Kit, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit, Mast/stem cell growth factor receptor Kit |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 374,00 €
CD117 (c-Kit), His-Tag Recombinant
Artikelnummer: BPS-83765-1
Recombinant human CD117, also known as c-Kit, encompassing amino acids 26-520, corresponding to the extracellular domain of the protein. This construct contains a C-terminal His-tag (6xHis). The protein was affinity purified. c-KIT is a proto-oncogene and a type III transmembrane receptor for mast cell growth...
| Schlagworte: | KIT, Mast/stem cell growth factor receptor Kit, Piebald trait protein, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit,... |
| Anwendung: | Binding studies |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 150+glyc. kD |
ab 367,00 €
Briquilimab
Artikelnummer: BPS-83766-1
Briquilimab, also known as JSP-191 or AMG-191, is a humanized IgG1 monoclonal antibody that targets CD117 (or c-Kit). Briquilimab blocks the interaction between CD117 receptor and stem cell factor. c-KIT is a proto-oncogene and a type III transmembrane receptor for mast cell growth factor, also known as stem cell...
| Schlagworte: | KIT, Mast/stem cell growth factor receptor Kit, Piebald trait protein, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit,... |
| Anwendung: | ELISA, FC, FA |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
ab 656,00 €
Anti-Recombinant c-Kit, clone A186
Artikelnummer: E-AN301491L.100
Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF...
| Schlagworte: | Anti-KIT, Anti-p145 c-kit, Anti-Proto-oncogene c-Kit, Anti-Piebald trait protein, Anti-Tyrosine-protein kinase Kit,... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 303,00 €
Anti-phospho-c-Kit (Tyr823)
Artikelnummer: NSJ-F48722-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell...
| Schlagworte: | Anti-phospho-KIT, Anti-phospho-p145 c-kit, Anti-phospho-Proto-oncogene c-Kit, Anti-phospho-Piebald trait protein,... |
| Anwendung: | DB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Anti-Zebrafish Kita / Kit / Scfr
Artikelnummer: NSJ-RZ1184
0.5mg/ml if reconstituted with 0.2ml sterile DI water. The Kit protein in zebrafish (Danio rerio), encoded by the kit gene (also referred to as kita or kitb depending on isoform), is a homolog of the mammalian c-Kit receptor, a type III receptor tyrosine kinase. Kit plays an essential role in multiple developmental...
| Schlagworte: | Anti-kita, Anti-Tyrosine-protein kinase Kit, Anti-Mast/stem cell growth factor receptor kita, Zebrafish Kita Antibody /... |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | zebrafish |
948,00 €
Mouse CD117 / c-Kit ELISA Kit
Artikelnummer: ARG81971.96
Protein function: Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In...
| Schlagworte: | Sl, Kit, SCFR, CD117, EC=2.7.10.1, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit, Mast/stem cell growth factor... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
1.118,00 €
cKit (V654A), active human recombinant protein
Artikelnummer: BPS-40251
Active human Kit Kit (V654A) ( GenBank Accession No. NM_000222), (a.a. 544- 976) with N-terminal His tag, MW=53.4 kDa, expressed in an Baculovirus infected Sf9 cell expression system.
| Schlagworte: | PBT, KIT, SCFR, CD117, p145 c-kit, EC=2.7.10.1, Proto-oncogene c-Kit, Piebald trait protein, Tyrosine-protein kinase Kit,... |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 53.4 kD |
536,00 €
Anti-CD117 (human), clone 57A5, Biotin conjugated
Artikelnummer: ANC-338-030
Human CD117 (c-kit) is a transmembrane protein with receptor tyrosine kinase capacity and serves as the receptor for steel factor (SLF). CD117 is expressed on almost all hematopoietic progenitor cells and receptor/ligand interaction is crucial for development of hematopoietic stem cells.
| Schlagworte: | Anti-KIT, Anti-PBT, Anti-SCFR, Anti-CD117, EC=2.7.10.1, Anti-p145 c-kit, Anti-Proto-oncogene c-Kit, Anti-Piebald trait... |
| Anwendung: | FC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
301,00 €
BLU-285
Artikelnummer: Cay22985-1
BLU-285 is a dual inhibitor of KIT receptor and platelet-derived growth factor receptor alpha (PDGFRalpha) tyrosine kinases with activating loop mutations (IC50s = 0.27 and 0.24 nM for KITD816V and PDGFRalphaD842V, respectively). It is >150-fold selective for KITD816V and PDGFRalphaD842V over a kinase panel at a...
| Schlagworte: | Avapritinib,... |
| Anwendung: | PDGFR alpha D842V / KIT Exon 17 mutant inhibitor |
| CAS | 1703793-34-3 |
| MW: | 498.6 D |
ab 51,00 €
Pazopanib
Artikelnummer: Cay12097-50
Pazopanib is a multi-kinase inhibitor that inhibits the VEGF receptors VEGFR1, VEGFR2, and VEGFR3 (IC50s = 10, 30, and 47 nM, respectively, in a cell-free enzyme assay). It also inhibits PDGFRalpha, PDGFRbeta, and c-Kit (IC50s = 71, 84, and 74 nM, respectively, in a cell-free enzyme assay) as well as additional...
| Schlagworte: | GSK-VEG10003, GW786034B, 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide |
| Anwendung: | Broad spectrum tyrosine kinase inhibitor |
| CAS | 444731-52-6 |
| MW: | 437.5 D |
ab 45,00 €