Zu "K05090" wurden 265 Artikel gefunden!
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NEU
Mouse CSF1R/M-CSFR ELISA Kit
Artikelnummer: SCC-EK0808
CSF1R (Colony stimulating factor 1 receptor), also known as M-CSFR and CD115, is a cell-surface protein encoded, in humans, by the CSF1R gene. The gene is located on the long arm of chromosome 5 (5q32) on the Crick (minus) strand. The encoded protein is a tyrosine kinase transmembrane receptor and a member of the...
| Schlagworte: | mCSF1R-ELISA, Csf1r, CSF-1 receptor, Proto-oncogene c-Fms, Macrophage colony-stimulating factor 1 receptor |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
632,00 €
NEU
Human CSF1R/M-CSFR ELISA Kit
Artikelnummer: SCC-EK0807
CSF1R (Colony stimulating factor 1 receptor), also known as M-CSFR and CD115, is a cell-surface protein encoded, in humans, by the CSF1R gene. The gene is located on the long arm of chromosome 5 (5q32) on the Crick (minus) strand. The encoded protein is a tyrosine kinase transmembrane receptor and a member of the...
| Schlagworte: | hCSF1R-ELISA, CSF1R, CSF-1 receptor, Proto-oncogene c-Fms, Macrophage colony-stimulating factor 1 receptor |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
701,00 €
GTP-14564
Artikelnummer: TGM-T71857-100mg
Description: GTP-14564 is a novel tyrosine kinase inhibitor that also inhibits wt-FLT3 and ITD-FLT3. GTP-14564 inhibits the growth of interleukin-3-independent Ba/F1 expressing ITD-FLT3 at 3 µ m, whereas a 30-fold higher concentration of GTP-14564 is required to inhibit the FLT3 ligand-dependent growth (wt-FLT3) of...
| Anwendung: | Class III receptor tyrosine kinase inhibitor |
| CAS | 34823-86-4 |
| MW: | 234.25 D |
ab 33,00 €
cFMS Receptor Inhibitor IV
Artikelnummer: TGM-T60087-100mg
Description: cFMS Receptor Inhibitor IV is an inhibitor of c-Fms tyrosine kinase. Target: c-Fms. Smiles: O=C(Nc1cc(ccc1N1CCCCC1)N1CCCCC1)c1ccc(o1)C#N. References: Patch RJ, et al. Potent 2'-aminoanilide inhibitors of cFMS as potential anti-inflammatory agents. Bioorg Med Chem Lett. 2007 Nov 15,17(22):6070-4.
| Schlagworte: | 5-cyano-N-(2,5-di(piperidin-1-yl)phenyl)furan-2-carboxamide |
| Anwendung: | cFMS (CSF1R) inhibitor |
| CAS | 959626-45-0 |
| MW: | 378.47 D |
ab 34,00 €
Anti-Recombinant CSF-1R, clone A195
Artikelnummer: E-AN301500L.100
Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory...
| Schlagworte: | Anti-CSF1R, Anti-CSF-1 receptor, Anti-Proto-oncogene c-Fms, Anti-Macrophage colony-stimulating factor 1 receptor,... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 303,00 €
Anti-Zebrafish Csf1r / M-csfr
Artikelnummer: NSJ-RZ1237
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Csf1r, or colony stimulating factor one receptor, is a transmembrane receptor tyrosine kinase that plays an essential role in the development, differentiation, and function of cells in the mononuclear phagocyte system, including macrophages and microglia. In...
| Schlagworte: | Anti-csf1r, Anti-CSF-1 receptor, Anti-Proto-oncogene c-Fms homolog, Anti-Macrophage colony-stimulating factor 1 receptor,... |
| Anwendung: | IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | zebrafish |
948,00 €
CSF-1R/CD115 (human, recombinant)
Artikelnummer: Cay44181-1
Colony-stimulating factor 1 receptor (CSF-1R), also known as CD115, is a single-pass transmembrane protein encoded by CSF1R, previously known as the c-fms proto-oncogene, in humans. It is composed of a glycosylated extracellular domain containing ligand-binding and dimerization regions, a transmembrane domain, and...
| Schlagworte: | c-Fms, FIM2, FMS, HDLS, Macrophage Colony-stimulating Factor 1 Receptor, McDonough Feline Sarcoma Viral Oncogene Homolog,... |
| Anwendung: | Active protein |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
ab 415,00 €
Human CSF-1R ELISA Kit
Artikelnummer: ARG81747.96
Protein function: Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of...
| Schlagworte: | FMS, CD115, CSF1R, CSF-1R, M-CSF-R, CSF-1-R, EC=2.7.10.1, CSF-1 receptor, Proto-oncogene c-Fms, Macrophage... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
1.118,00 €
Mouse CSF-1R ELISA Kit
Artikelnummer: ARG81748.96
Protein function: Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of...
| Schlagworte: | CD115, Csf1r, Csfmr, CSF-1R, M-CSF-R, CSF-1-R, EC=2.7.10.1, CSF-1 receptor, Proto-oncogene c-Fms, Macrophage... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
1.118,00 €
Vimseltinib
Artikelnummer: Cay38783-25
Vimseltinib is an inhibitor of colony stimulating factor 1 receptor (CSF1R, IC50 = 3.7 nM). It is selective for CSF1R over FMS-related tyrosine kinase 3 (FLT3), PDGFRalpha, PDGFRbeta, and KIT (IC50s = >3,300, 436, 2,300, and 476 nM, respectively). Vimseltinib inhibits the proliferation of M-NFS-60 leukemia cells...
| Schlagworte: | DCC-3014,... |
| Anwendung: | CSF1R inhibitor |
| CAS | 1628606-05-2 |
| MW: | 431.5 D |
ab 72,00 €
GW 2580
Artikelnummer: Cay15411-25
cFMS kinase is the cellular homolog of the v-FMS oncogene product of the Susan McDonough strain of the feline sarcoma virus. It can autophosphorlyate colony-stimulating factor (CSF-1), which promotes the survival, proliferation, and differentiation of mononuclear phagocytes. GW 2580 selectively inhibits cFMS kinase...
| Schlagworte: | 5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]-2,4-pyrimidinediamine |
| Anwendung: | CSF1R kinase inhibitor |
| CAS | 870483-87-7 |
| MW: | 366.4 D |
ab 58,00 €
cFMS Receptor Tyrosine Kinase Inhibitor
Artikelnummer: Cay44282-10
cFMS receptor tyrosine kinase inhibitor is an inhibitor of CSF-1 receptor tyrosine kinase (FMS, IC50 = 0. µM). InChI: InChI=1S/C22H26N4O2/c23-16-18-8-10-21(28-18)22(27)24-19-15-17(25-11-3-1-4-12-25)7-9-20(19)26-13-5-2-6-14-26/h7-10,15H,1-6,11-14H2,(H,24,27), InChIKey: FQGXFVDABCBEFW-UHFFFAOYSA-N, SMILES:...
| Schlagworte: | 5-cyano-N-(2,5-di-1-piperidinylphenyl)-2-furancarboxamide |
| Anwendung: | CSF-1 receptor tyrosine kinase (FMS) inhibitor |
| CAS | 959626-45-0 |
| MW: | 378.48 D |
ab 89,00 €