Zu "K05090" wurden 266 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
CSF-1R/CD115 (human, recombinant)
Artikelnummer: Cay44181-1
Colony-stimulating factor 1 receptor (CSF-1R), also known as CD115, is a single-pass transmembrane protein encoded by CSF1R, previously known as the c-fms proto-oncogene, in humans. It is composed of a glycosylated extracellular domain containing ligand-binding and dimerization regions, a transmembrane domain, and...
| Schlagworte: | c-Fms, FIM2, FMS, HDLS, Macrophage Colony-stimulating Factor 1 Receptor, McDonough Feline Sarcoma Viral Oncogene Homolog,... |
| Anwendung: | Active protein |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
ab 415,00 €
Anti-Recombinant CSF-1R, clone A195
Artikelnummer: E-AN301500L.100
Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory...
| Schlagworte: | Anti-CSF1R, Anti-CSF-1 receptor, Anti-Proto-oncogene c-Fms, Anti-Macrophage colony-stimulating factor 1 receptor,... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 304,00 €
Anti-Zebrafish Csf1r / M-csfr
Artikelnummer: NSJ-RZ1237
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Csf1r, or colony stimulating factor one receptor, is a transmembrane receptor tyrosine kinase that plays an essential role in the development, differentiation, and function of cells in the mononuclear phagocyte system, including macrophages and microglia. In...
| Schlagworte: | Anti-csf1r, Anti-CSF-1 receptor, Anti-Proto-oncogene c-Fms homolog, Anti-Macrophage colony-stimulating factor 1 receptor,... |
| Anwendung: | IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | zebrafish |
948,00 €
Human CSF-1R ELISA Kit
Artikelnummer: ARG81747.96
Protein function: Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of...
| Schlagworte: | FMS, CD115, CSF1R, CSF-1R, M-CSF-R, CSF-1-R, EC=2.7.10.1, CSF-1 receptor, Proto-oncogene c-Fms, Macrophage... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
1.118,00 €
Mouse CSF-1R ELISA Kit
Artikelnummer: ARG81748.96
Protein function: Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of...
| Schlagworte: | CD115, Csf1r, Csfmr, CSF-1R, M-CSF-R, CSF-1-R, EC=2.7.10.1, CSF-1 receptor, Proto-oncogene c-Fms, Macrophage... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
1.118,00 €
cFMS Receptor Tyrosine Kinase Inhibitor
Artikelnummer: Cay44282-10
cFMS receptor tyrosine kinase inhibitor is an inhibitor of CSF-1 receptor tyrosine kinase (FMS, IC50 = 0. µM). InChI: InChI=1S/C22H26N4O2/c23-16-18-8-10-21(28-18)22(27)24-19-15-17(25-11-3-1-4-12-25)7-9-20(19)26-13-5-2-6-14-26/h7-10,15H,1-6,11-14H2,(H,24,27), InChIKey: FQGXFVDABCBEFW-UHFFFAOYSA-N, SMILES:...
| Schlagworte: | 5-cyano-N-(2,5-di-1-piperidinylphenyl)-2-furancarboxamide |
| Anwendung: | CSF-1 receptor tyrosine kinase (FMS) inhibitor |
| CAS | 959626-45-0 |
| MW: | 378.48 D |
ab 89,00 €
GW 2580
Artikelnummer: Cay15411-25
cFMS kinase is the cellular homolog of the v-FMS oncogene product of the Susan McDonough strain of the feline sarcoma virus. It can autophosphorlyate colony-stimulating factor (CSF-1), which promotes the survival, proliferation, and differentiation of mononuclear phagocytes. GW 2580 selectively inhibits cFMS kinase...
| Schlagworte: | 5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]-2,4-pyrimidinediamine |
| Anwendung: | CSF1R kinase inhibitor |
| CAS | 870483-87-7 |
| MW: | 366.4 D |
ab 58,00 €
PLX5622
Artikelnummer: Cay28927-25
5-fluoro-N-[6-fluoro-5-[(5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-2-pyridinyl]-2-methoxy-3-pyridinemethanamine
| Schlagworte: | 5-fluoro-N-[6-fluoro-5-[(5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-2-pyridinyl]-2-methoxy-3-pyridinemethanamine |
| Anwendung: | CSF1R inhibitor |
| CAS | 1303420-67-8 |
| MW: | 395.4 D |
ab 145,00 €
Vimseltinib
Artikelnummer: Cay38783-25
Vimseltinib is an inhibitor of colony stimulating factor 1 receptor (CSF1R, IC50 = 3.7 nM). It is selective for CSF1R over FMS-related tyrosine kinase 3 (FLT3), PDGFRalpha, PDGFRbeta, and KIT (IC50s = >3,300, 436, 2,300, and 476 nM, respectively). Vimseltinib inhibits the proliferation of M-NFS-60 leukemia cells...
| Schlagworte: | DCC-3014,... |
| Anwendung: | CSF1R inhibitor |
| CAS | 1628606-05-2 |
| MW: | 431.5 D |
ab 72,00 €
Ki20227
Artikelnummer: Cay22258-1
Ki20227 is an inhibitor of macrophage colony stimulating factor 1 (CSF1) receptor tyrosine kinase (c-Fms, IC50 = 2 nM). It inhibits CSF1-dependent c-Fms phosphorylation in a dose-dependent manner in RAW264.7 cells and reduces CSF1-dependent growth of M-NFS-60 cells (IC50 = 14 nM). Ki20227 suppresses development of...
| Schlagworte: | N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]-2-methoxyphenyl]-N'-[1-(2-thiazolyl)ethyl]-urea |
| Anwendung: | CSF-1 receptor inhibitor |
| CAS | 623142-96-1 |
| MW: | 480.5 D |
ab 53,00 €
BLZ-945
Artikelnummer: Cay19626-1
BLZ-945 is a selective inhibitor of the colony stimulating factor 1 receptor (CSF1R) with an IC50 value of 1 nM. It is more than 1,000-fold selective against its closest receptor tyrosine kinase homologs. It has been shown to inhibit CSF1-dependent proliferation with an EC50 value of 67 nM in bone marrow-derived...
| Schlagworte: | 4-[[2-[[(1R,2R)-2-hydroxycyclohexyl]amino]-6-benzothiazolyl]oxy]-N-methyl-2-pyridinecarboxamide |
| Anwendung: | Anticancer compound, CSF-1R / c-Fms inhibitor |
| CAS | 953769-46-5 |
| MW: | 398.5 D |
ab 40,00 €
BLZ-945
Artikelnummer: SYN-1197-M001
Soluble in DMSO. BLZ945 is an orally active, potent and selective CSF-1R inhibitor, which inhibits CSF-1R activity with an IC(50) of 1nM and is more than 1000-fold selective against its closest receptor tyrosine kinase homologs c-KIT and Platelet-derived Growth Factor Receptor beta (PDGFRbeta ) as well as more than...
| Schlagworte: | BLZ945 |
| Anwendung: | CSF1R / c-FMS inhibitor |
| CAS | 953769-46-5 |
| MW: | 398,5 D |
ab 246,00 €