Zu "K05085" wurden 106 Artikel gefunden!
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Anti-HER4 / ERBB4
Artikelnummer: NSJ-RQ8802
0.5mg/ml if reconstituted with 0.2ml sterile DI water. ERBB4 (V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4) also known as ONCOGENE ERBB4 or HER4, is an enzyme that in humans is encoded by the ERBB4 gene. The HER4/ERBB4 gene is a member of the type I receptor tyrosine kinase subfamily that includes...
| Schlagworte: | Anti-ERBB4, Anti-p180erbB4, Anti-Proto-oncogene-like protein c-ErbB-4, Anti-Receptor tyrosine-protein kinase erbB-4,... |
| Anwendung: | WB, IHC (paraffin), ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-Recombinant HER4/ErbB4, clone A584
Artikelnummer: E-AN301872L.100
HER4/ErbB4, like other receptor tyrosine kinase family members, has four ectodomains, a single transmembrane domain and a cytoplasmic tail containing the active tyrosine kinase domain. By binding to neuregulins and/or EGF family ligands, ErbB4 forms either a homodimer or heterodimer with other ErbB family members,...
| Schlagworte: | Anti-ERBB4, Anti-p180erbB4, Anti-Proto-oncogene-like protein c-ErbB-4, Anti-Receptor tyrosine-protein kinase erbB-4,... |
| Anwendung: | IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 304,00 €
Her4/ErbB4, His & Avi, Human
Artikelnummer: GSC-Z05372-100
Her4, a member of the EGF receptor family, plays a variety of roles in physiological and pathological states. Genetic studies have indicated a link between Her4 and type 2 diabetes and obesity. Her4 may play an important role in glucose homeostasis and lipogenesis. Her4 deficiency-related obesity and adipose tissue...
| Schlagworte: | ERBB4, p180erbB4, Proto-oncogene-like protein c-ErbB-4, Receptor tyrosine-protein kinase erbB-4, Tyrosine kinase-type cell... |
| Ursprungsart: | human |
| MW: | 72.7 kD |
ab 376,00 €
Her4/ErbB4 hFc Chimera, Human
Artikelnummer: GSC-Z05373-100
ErbB4, a member of the EGF receptor family, plays a variety of roles in physiological and pathological states. Genetic studies have indicated a link between ErbB4 and type 2 diabetes and obesity. ErbB4 may play an important role in glucose homeostasis and lipogenesis. ErbB4 deficiency-related obesity and adipose...
| Schlagworte: | ERBB4, p180erbB4, Proto-oncogene-like protein c-ErbB-4, Receptor tyrosine-protein kinase erbB-4, Tyrosine kinase-type cell... |
| Ursprungsart: | human |
| MW: | 96.6 kD |
ab 363,00 €
![Her4/ErbB4[Biotin], His & Avi, Human](https://www.biomol.com/media/image/34/c1/3f/GSC-Z04477-100_200x200.png "Her4/ErbB4[Biotin], His & Avi, Human")
Her4/ErbB4[Biotin], His & Avi, Human
Artikelnummer: GSC-Z04477-100
Her4, a member of the EGF receptor family, plays a variety of roles in physiological and pathological states. Genetic studies have indicated a link between Her4 and type 2 diabetes and obesity. Her4 may play an important role in glucose homeostasis and lipogenesis. Her4 deficiency-related obesity and adipose tissue...
| Schlagworte: | ERBB4, p180erbB4, Proto-oncogene-like protein c-ErbB-4, Receptor tyrosine-protein kinase erbB-4, Tyrosine kinase-type cell... |
| Ursprungsart: | human |
| MW: | 72.7 kD |
ab 887,00 €
Anti-ErbB4
Artikelnummer: ARG52859.500
Protein function: Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins and EGF family members and regulates development of the heart, the central nervous system and the mammary gland, gene transcription, cell proliferation, differentiation, migration and apoptosis. Required...
| Schlagworte: | Anti-HER4, Anti-ERBB4, EC=2.7.10.1 |
| Anwendung: | IHC (paraffin), IP, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
625,00 €
Anti-phospho-ERBB4 / HER4 (Tyr1162)
Artikelnummer: ARG55922.100
Protein function: Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins and EGF family members and regulates development of the heart, the central nervous system and the mammary gland, gene transcription, cell proliferation, differentiation, migration and apoptosis. Required...
| Schlagworte: | Anti-phospho-HER4, Anti-phospho-ERBB4, EC=2.7.10.1 |
| Anwendung: | WB, IHC (paraffin), ICC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
616,00 €
Anti-ErbB4
Artikelnummer: A300-666A
Protein function: Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins and EGF family members and regulates development of the heart, the central nervous system and the mammary gland, gene transcription, cell proliferation, differentiation, migration and apoptosis. Required...
| Schlagworte: | Anti-HER4, Anti-ERBB4, EC=2.7.10.1 |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Her4, active human recombinant protein
Artikelnummer: BPS-40232
Active human HER4 kinase (ERBB4) (GenBank Accession No. NM_005235), amino acids 708-993, MW=59.5 kDa, expressed in an Baculovirus infected Sf9 cell expression system. Assay condition: The enzyme reaction was carried out at 37° C for 20 min in a buffer containing 20 mM of Tris-HCl, pH 7.4, 10 mM of MgCl2, 1 mM of...
| Schlagworte: | HER4, ERBB4, EC=2.7.10.1, |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 59.5 kD |
536,00 €
Anti-ERBB4 (HER4)
Artikelnummer: NSJ-R30981
0.5mg/ml if reconstituted with 0.2ml sterile DI water. V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4, also known as HER4, is an enzyme that in humans is encoded by the ERBB4 gene. The HER4/ERBB4 gene is a member of the type I receptor tyrosine kinase subfamily that includes EGFR, ERBB2 and ERBB3....
| Schlagworte: | Anti-HER4, Anti-ERBB4, EC=2.7.10.1, ERBB4 Antibody (HER4) |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-ERBB4
Artikelnummer: NSJ-F40046-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. ERBB4 acts as cell-surface receptor for the neuregulins NRG1, NRG2, NRG3 and NRG4 and the EGF family members BTC, EREG and HBEGF. Ligand binding triggers receptor dimerization and autophosphorylation at specific tyrosine residues that then serve as binding sites for...
| Schlagworte: | Anti-HER4, Anti-ERBB4, EC=2.7.10.1, ERBB4 Antibody |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 361,00 €
PF-299804
Artikelnummer: Cay9001879-5
The epidermal growth factor receptors (EGFR), whose members include ErbB1 (HER1), ErbB2 (HER2), ErbB3 (HER3), and ErbB4 (HER4), are receptor tyrosine kinases that are often over-expressed in cancer. PF-299804 is a second generation pan-ErbB receptor tyrosine kinase inhibitor (IC50s = 6, 45.7, and 73.7 nM for ErbB1,...
| Schlagworte: | Dacomitinib, PF299, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-4-(1-piperidinyl)-(2E)-butenamide |
| Anwendung: | pan-erbB receptor tyrosine kinase inhibitor |
| CAS | 1110813-31-4 |
| MW: | 469.9 D |
ab 68,00 €