Zu "K05085" wurden 82 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
Anti-ErbB4
Artikelnummer: ARG52859.500
Protein function: Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins and EGF family members and regulates development of the heart, the central nervous system and the mammary gland, gene transcription, cell proliferation, differentiation, migration and apoptosis. Required...
| Schlagworte: | Anti-HER4, Anti-ERBB4, EC=2.7.10.1 |
| Anwendung: | IHC (paraffin), IP, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
608,00 €
Anti-phospho-ERBB4 / HER4 (Tyr1162)
Artikelnummer: ARG55922.100
Protein function: Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins and EGF family members and regulates development of the heart, the central nervous system and the mammary gland, gene transcription, cell proliferation, differentiation, migration and apoptosis. Required...
| Schlagworte: | Anti-phospho-HER4, Anti-phospho-ERBB4, EC=2.7.10.1 |
| Anwendung: | WB, IHC (paraffin), ICC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
584,00 €
Anti-ErbB4
Artikelnummer: A300-666A
Protein function: Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins and EGF family members and regulates development of the heart, the central nervous system and the mammary gland, gene transcription, cell proliferation, differentiation, migration and apoptosis. Required...
| Schlagworte: | Anti-HER4, Anti-ERBB4, EC=2.7.10.1 |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Her4, active human recombinant protein
Artikelnummer: BPS-40232
Active human HER4 kinase (ERBB4) (GenBank Accession No. NM_005235), amino acids 708-993, MW=59.5 kDa, expressed in an Baculovirus infected Sf9 cell expression system. Assay condition: The enzyme reaction was carried out at 37° C for 20 min in a buffer containing 20 mM of Tris-HCl, pH 7.4, 10 mM of MgCl2, 1 mM of...
| Schlagworte: | HER4, ERBB4, EC=2.7.10.1, |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 59.5 kD |
525,00 €
Anti-ErbB4 (amino acids 1230-1250), clone 6C5
Artikelnummer: 0228-100
| Schlagworte: | Anti-HER4, Receptor tyrosine-protein kinase erbB-4, EC=2.7.10.1 |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
383,00 €
Anti-phospho-ErbB4 (Tyr1242), clone 4C6
Artikelnummer: 0229-100
| Schlagworte: | Anti-phospho-HER4 (pY1242) |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
383,00 €
Anti-ERBB4 (HER4)
Artikelnummer: NSJ-R30981
0.5mg/ml if reconstituted with 0.2ml sterile DI water. V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4, also known as HER4, is an enzyme that in humans is encoded by the ERBB4 gene. The HER4/ERBB4 gene is a member of the type I receptor tyrosine kinase subfamily that includes EGFR, ERBB2 and ERBB3....
| Schlagworte: | Anti-HER4, Anti-ERBB4, EC=2.7.10.1, ERBB4 Antibody (HER4) |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
755,00 €
Afatinib (maleate)
Artikelnummer: Cay21567-5
Afatinib is an irreversible inhibitor of epidermal growth factor receptor (EGFR) and ErbB2 (IC50s = 0.5 and 14 nM, respectively). It increases the cytotoxicity of adriamycin in a concentration-dependent manner in multidrug-resistant A549T lung cancer cells overexpressing P-glycoprotein. Afatinib (20 mg/kg) reduces...
| Schlagworte: | Afatinib dimaleate, BIBW 2992, BIBW 2992MA2,... |
| Anwendung: | EGFR / ERBB2 / ERBB4 inhibitor |
| CAS | 850140-73-7 |
| MW: | 718.1 D |
ab 125,00 €
Anti-ERBB4
Artikelnummer: NSJ-F40046-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. ERBB4 acts as cell-surface receptor for the neuregulins NRG1, NRG2, NRG3 and NRG4 and the EGF family members BTC, EREG and HBEGF. Ligand binding triggers receptor dimerization and autophosphorylation at specific tyrosine residues that then serve as binding sites for...
| Schlagworte: | Anti-HER4, Anti-ERBB4, EC=2.7.10.1, ERBB4 Antibody |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 326,00 €
PF-299804
Artikelnummer: Cay9001879-5
The epidermal growth factor receptors (EGFR), whose members include ErbB1 (HER1), ErbB2 (HER2), ErbB3 (HER3), and ErbB4 (HER4), are receptor tyrosine kinases that are often over-expressed in cancer. PF-299804 is a second generation pan-ErbB receptor tyrosine kinase inhibitor (IC50s = 6, 45.7, and 73.7 nM for ErbB1,...
| Schlagworte: | Dacomitinib, PF299, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-4-(1-piperidinyl)-(2E)-butenamide |
| Anwendung: | pan-erbB receptor tyrosine kinase inhibitor |
| CAS | 1110813-31-4 |
| MW: | 469.9 D |
ab 60,00 €
Anti-ERBB4
Artikelnummer: E-AB-10231.120
This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding...
| Schlagworte: | Anti-HER4, Anti-ERBB4, EC=2.7.10.1, ERBB4 Polyclonal Antibody |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 71,00 €
Anti-ERBB4
Artikelnummer: E-AB-13998.120
This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding...
| Schlagworte: | Anti-HER4, Anti-ERBB4, EC=2.7.10.1, ERBB4 Polyclonal Antibody |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 71,00 €