Zu "K05084" wurden 204 Artikel gefunden!
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NEU
Recombinant Human ErbB3 Fragment
Artikelnummer: SCC-107-11
ErbB3 is one of four alphaembers of the epidermal growth factor (EGF) receptor family with no intrinsic kinase activity. Therefore, its signal transduction upon EGF ligand binding is carried by the heterodimerization of ErbB3 with a different EGF receptor kinase. ErbB3 is linked to cancer etiology and progression....
| Schlagworte: | rhErbB3-f, HER3, ERBB3, Proto-oncogene-like protein c-ErbB-3, Receptor tyrosine-protein kinase erbB-3, Tyrosine... |
| Ursprungsart: | human |
ab 126,00 €
NEU
Anti-Recombinant ErbB 3, clone C222779
Artikelnummer: E-AN303159L.100
Protein function: Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it, ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase...
| Schlagworte: | Anti-ERBB3, Anti-Proto-oncogene-like protein c-ErbB-3, Anti-Receptor tyrosine-protein kinase erbB-3, Anti-Tyrosine... |
| Anwendung: | WB, IHC, FCM |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human,mouse |
ab 171,00 €
Anti-HER3 Antibody (Ab562)
Artikelnummer: BPS-84318-1
Anti-HER3 (human epidermal growth factor receptor 3) antibody Ab562 is a monoclonal antibody that is part of the ADC (antibody drug conjugate) AMT-562. HER3 (human epidermal growth factor receptor 3) is a transmembrane protein encoded by the ERB3 gene. HER3 is broadly expressed in human tissues however, increased...
| Schlagworte: | ERBB3, Receptor tyrosine-protein kinase erbB-3, Proto-oncogene-like protein c-ErbB-3, Tyrosine kinase-type cell surface... |
| Anwendung: | ELISA, FC, FA, ADC synthesis |
ab 784,00 €
Anti-HER3 Antibody (Patritumab)
Artikelnummer: BPS-84316-1
Patritumab (BPS Bioscience #84316) is a component of the ADC(antibody drug conjugate) Patritumab Deruxtecan (BPS Bioscience #84315) and also functions as neutralizing monoclonal antibody targeting HER3 (human epidermal growth factor receptor 3). HER3 (human epidermal growth factor receptor 3) is a transmembrane...
| Schlagworte: | ERBB3, Receptor tyrosine-protein kinase erbB-3, Proto-oncogene-like protein c-ErbB-3, Tyrosine kinase-type cell surface... |
| Anwendung: | ELISA, FC, FA, ADC synthesis |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
| CAS | 1262787-83-6 |
ab 1.038,00 €
Anti-Recombinant Phospho-ErbB-3 (Tyr1289), clone 11A5
Artikelnummer: E-AN301394L.100
This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation....
| Schlagworte: | Anti-ERBB3, Anti-Proto-oncogene-like protein c-ErbB-3, Anti-Receptor tyrosine-protein kinase erbB-3, Anti-Tyrosine... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
389,00 €
Anti-Recombinant c-erbB-3/HER-3, clone A215
Artikelnummer: E-AN301516L.100
Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it, ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase. May also be activated...
| Schlagworte: | Anti-ERBB3, Anti-Proto-oncogene-like protein c-ErbB-3, Anti-Receptor tyrosine-protein kinase erbB-3, Anti-Tyrosine... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 303,00 €
Human ERBB3 / HER3 ELISA Kit
Artikelnummer: ARG81570.96
Protein function: Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it, ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase...
| Schlagworte: | HER3, ERBB3, EC=2.7.10.1, Proto-oncogene-like protein c-ErbB-3, Receptor tyrosine-protein kinase erbB-3, Tyrosine... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
1.118,00 €
TX1-85-1
Artikelnummer: Cay19164-1
TX1-85-1 is an inhibitor of the epidermal growth factor receptor tyrosine kinase ErbB3 (IC50 = 23 nM). It also binds to ErbB2, Lyn, and several other Src family kinases in a live cell chemical proteomics assay when used at a concentration of 2 µM. TX1-85-1 inhibits phosphorylation of Akt and ERK1/2 in...
| Schlagworte: | N-[5-[1-[4-(4-acetyl-1-piperazinyl)cyclohexyl]-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-2-phenoxyphenyl]-2-propenamide |
| Anwendung: | ErbB3 inhibitor |
| CAS | 1603845-32-4 |
| MW: | 580.7 D |
ab 164,00 €
Human HER3 Protein, His Tag
Artikelnummer: DIM-PME100088.50
Recombinant Human HER3 protein with C-terminal 6×His tag. HER3(Ser20-Thr643) 6×His tag, Protein function: Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it, ligand-binding increases phosphorylation on tyrosine residues...
| Schlagworte: | HER3, ERBB3 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 69.39 kD |
ab 124,00 €
Anti-phospho-Her3/ErbB3 (Tyr1328)
Artikelnummer: ARG51811.100
Protein function: Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it, ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase...
| Schlagworte: | Anti-phospho-HER3, Anti-phospho-ERBB3, EC=2.7.10.1, Anti-phospho-Proto-oncogene-like protein c-ErbB-3,... |
| Anwendung: | ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 471,00 €
Anti-c-erbB-3/HER-3
Artikelnummer: ARG52855.500
Protein function: Binds and is activated by neuregulins and NTAK. May also be activated by CSPG5. [The UniProt Consortium]
| Schlagworte: | Anti-HER3, Anti-ERBB3, EC=2.7.10.1, Anti-Proto-oncogene-like protein c-ErbB-3, Anti-Receptor tyrosine-protein kinase... |
| Anwendung: | IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
625,00 €
Anti-HER3 / ErbB3
Artikelnummer: ARG55546.100
Protein function: Binds and is activated by neuregulins and NTAK. May also be activated by CSPG5. [The UniProt Consortium]
| Schlagworte: | Anti-HER3, Anti-ERBB3, EC=2.7.10.1, Anti-Proto-oncogene-like protein c-ErbB-3, Anti-Receptor tyrosine-protein kinase... |
| Anwendung: | FC, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
616,00 €