Zu "K05083" wurden 490 Artikel gefunden!
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Anti-ErbB2
Artikelnummer: A300-621A-T
ErbB2 is a member of the receptor tyrosine kinase family of proteins. The four members of this family are ErbB1 (Epidermal growth factor receptor, EGFR/HER1), ErbB2 (HER2/Neu), ErbB3 (HER3), and ErbB4 (HER4). The ErbB receptor members are single-pass transmembrane proteins with an extracellular ligand-binding domain...
| Schlagworte: | Anti-HER2, Anti-CD340, Anti-ERBB2, Anti-MLN 19, Anti-p185erbB2, EC=2.7.10.1, Anti-Proto-oncogene Neu, Anti-Proto-oncogene... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
164,00 €
Anti-ErbB2
Artikelnummer: A300-622A-T
ErbB2 is a member of the receptor tyrosine kinase family of proteins. The four members of this family are ErbB1 (Epidermal growth factor receptor, EGFR/HER1), ErbB2 (HER2/Neu), ErbB3 (HER3), and ErbB4 (HER4). The ErbB receptor members are single-pass transmembrane proteins with an extracellular ligand-binding domain...
| Schlagworte: | Anti-HER2, Anti-CD340, Anti-ERBB2, Anti-MLN 19, Anti-p185erbB2, EC=2.7.10.1, Anti-Proto-oncogene Neu, Anti-Proto-oncogene... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
164,00 €
Anti-ErbB2
Artikelnummer: A300-623A-T
ErbB2 is a member of the receptor tyrosine kinase family of proteins. The four members of this family are ErbB1 (Epidermal growth factor receptor, EGFR/HER1), ErbB2 (HER2/Neu), ErbB3 (HER3), and ErbB4 (HER4). The ErbB receptor members are single-pass transmembrane proteins with an extracellular ligand-binding domain...
| Schlagworte: | Anti-HER2, Anti-CD340, Anti-ERBB2, Anti-MLN 19, Anti-p185erbB2, EC=2.7.10.1, Anti-Proto-oncogene Neu, Anti-Proto-oncogene... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
164,00 €
Anti-HER2 / ErbB2 / C-terminal region
Artikelnummer: NSJ-F54939-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. ErbB2, a member of the EGF receptor family, is an essential component of a neuregulin-receptor complex, althought neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. This protein is not activated by EGF, TGF-alpha and amphiregulin....
| Schlagworte: | Anti-HER2, Anti-ERBB2, Anti-CD340, Anti-MLN 19, Anti-p185erbB2, EC=2.7.10.1, Anti-Proto-oncogene Neu, Anti-Proto-oncogene... |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 326,00 €
Anti-HER2 / ErbB2
Artikelnummer: NSJ-RQ7075
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Receptor tyrosine-protein kinase erbB-2, also known as CD340 (cluster of differentiation 340), proto-oncogene Neu, Erbb2 (rodent), or ERBB2 (human), is a protein that in humans is encoded by the ERBB2 gene. And it is also frequently called HER2 (from human...
| Schlagworte: | Anti-HER2, Anti-ERBB2, Anti-CD340, Anti-MLN 19, Anti-p185erbB2, EC=2.7.10.1, Anti-Proto-oncogene Neu, Anti-Proto-oncogene... |
| Anwendung: | WB, IHC (paraffin), Direct ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
755,00 €
Anti-HER2 / ErbB2
Artikelnummer: NSJ-RQ7168
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Receptor tyrosine-protein kinase erbB-2, also known as CD340 (cluster of differentiation 340), proto-oncogene Neu, Erbb2 (rodent), or ERBB2 (human), is a protein that in humans is encoded by the ERBB2 gene. And it is also frequently called HER2 (from human...
| Schlagworte: | Anti-HER2, Anti-ERBB2, Anti-CD340, Anti-MLN 19, Anti-p185erbB2, EC=2.7.10.1, Anti-Proto-oncogene Neu, Anti-Proto-oncogene... |
| Anwendung: | WB, IHC (paraffin), FC, Direct ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
755,00 €
Anti-HER-2 (Trastuzumab Biosimilar In Vivo Antibody)
Artikelnummer: G-IVMB0215.1
Endotoxin level: < 1.0 EU/mg as determined by the LAL method. Protein function: Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with...
| Schlagworte: | Anti-HER2, Anti-ERBB2, Anti-CD340, Anti-MLN 19, Anti-p185erbB2, EC=2.7.10.1, Anti-Proto-oncogene Neu, Anti-Proto-oncogene... |
| Anwendung: | CyTOF ELISA, FC, IHC |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
ab 266,00 €
Anti-HER-2 (Trastuzumab Biosimilar In Vivo Antibody (Fc...
Artikelnummer: G-IVMB0216.500
Endotoxin level: < 1.0 EU/mg as determined by the LAL method. Protein function: Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with...
| Schlagworte: | Anti-HER2, Anti-ERBB2, Anti-CD340, Anti-MLN 19, Anti-p185erbB2, EC=2.7.10.1, Anti-Proto-oncogene Neu, Anti-Proto-oncogene... |
| Anwendung: | CyTOF, ELISA, FC, IHC |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
620,00 €
Lapatinib
Artikelnummer: Cay11493-5
Lapatinib is a dual inhibitor of the EGF receptor (EGFR) and ErbB2 (IC50s = 19 and 3 nM, respectively). It inhibits the growth of EGFR-overexpressing A431 skin cancer and ErbB2-overexpressing SK-BR-3 breast cancer cells (IC50s = 0.14 and 0.124 µM, respectively). Lapatinib also inhibits the growth of ErbB2-amplified...
| Schlagworte: | GSK 572016, GW 572016,... |
| Anwendung: | EGFR / HER2 inhibitor |
| CAS | 231277-92-2 |
| MW: | 581.1 D |
ab 77,00 €
Afatinib
Artikelnummer: Cay11492-5
Afatinib is an irreversible inhibitor of epidermal growth factor receptor (EGFR) and ErbB2 (IC50s = 0.5 and 14 nM, respectively). It increases the cytotoxicity of adriamycin in a concentration-dependent manner in multidrug-resistant A549T lung cancer cells overexpressing P-glycoprotein. Afatinib (20 mg/kg) reduces...
| Schlagworte: | BIBW 2992,... |
| Anwendung: | EGFR / HER2 kinase inhibitor |
| CAS | 850140-72-6 |
| MW: | 485.9 D |
ab 35,00 €
Afatinib
Artikelnummer: LKT-A2077.5
Afatanib is an anticancer chemotherapeutic compound that has been approved to treat advanced lung cancers such as non-small cell lung cancer (NSCLC) and is in clinical trials as a potential treatment for other advanced solid tumors such as breast cancer and colorectal cancer. Afatanib exerts its anticancer activity...
| Schlagworte: | BIBW 2992 |
| Anwendung: | EGFR / ErbB2 inhibitor |
| MW: | 485.94 D |
ab 167,00 €
AG-879
Artikelnummer: Cay10793-5
Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds which selectively inhibit PTKs of key growth factors. AG-879 is a tyrphostin compound that inhibits nerve growth factor...
| Schlagworte: | Tyrphostin AG-879, 3-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-cyano-2E-propenethioamide |
| Anwendung: | Tyrosine kinase inhibitor |
| CAS | 148741-30-4 |
| MW: | 316.5 D |
ab 86,00 €