Zu "K05060" wurden 122 Artikel gefunden!
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Glycoprotein 130 Extracellular Domain (human, recombinant)
Artikelnummer: Cay43755-100
Glycoprotein 130 (gp130), also known as IL-6 signal transducer (IL6ST), is a single-pass type I membrane protein and shared signal transducing receptor for the IL-6 cytokine family. It is composed of an N-terminal immunoglobulin-like domain, two cytokine-binding domains, three fibronectin type III-like domains, a...
| Schlagworte: | gp130/IL6ST, CD130, CDw130, gp130, IL-6 Receptor Subunit beta, IL-6R Subunit beta, IL-6RB, Interleukin-6 Receptor Subunit... |
| Anwendung: | Active protein |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
ab 177,00 €
Anti-CD130 / IL6ST / Interleukin 6 Receptor subunit beta
Artikelnummer: NSJ-F54230-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex....
| Schlagworte: | Anti-IL6ST, Anti-CDw130, Anti-Membrane glycoprotein 130, Anti-Interleukin-6 signal transducer, Anti-Interleukin-6 receptor... |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Mouse CD130 / gp130 ELISA Kit
Artikelnummer: ARG81687.96
Protein function: Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates Janus kinases...
| Schlagworte: | gp130, Il6st, CD130, IL-6RB, IL-6R-beta, IL-6R subunit beta, Membrane glycoprotein 130, IL-6 receptor subunit beta,... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
1.118,00 €
Human CD130 ELISA Kit
Artikelnummer: ARG81316.96
Protein function: Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates Janus kinases...
| Schlagworte: | gp130, IL6ST, CD130, IL-6RB, CDw130, IL-6R-beta, IL-6R subunit beta, Membrane glycoprotein 130, IL-6 receptor subunit... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
1.118,00 €
gp130/CD130/IL-6 R beta, His, Human
Artikelnummer: GSC-Z05364-100
gp130 is a common signal transducing component of the functional receptor complexes for the interleukin (IL)-6 family of cytokines, ie, IL-6, IL-11, leukemia inhibitory factor (LIF), oncostatin M, ciliary neurotrophic factor, and cardiotrophin-1. These cytokines exhibit pleiotropic biological activities in, for...
| Schlagworte: | IL6ST, CDw130, Membrane glycoprotein 130, Interleukin-6 signal transducer, Oncostatin-M receptor subunit alpha,... |
| Ursprungsart: | human |
| MW: | 68.94 kD |
ab 403,00 €
gp130/CD130/IL-6 R beta, His, Mouse
Artikelnummer: GSC-Z06151-100
Glycoprotein 130 (gp130) is a shared receptor utilized by several related cytokines, including IL-6, IL-11, IL-27, Leukemia Inhibitory Factor (LIF), Oncostatin M (OSM), Ciliary Neurotrophic Factor (CNTF), Cardiotrophin 1 (CT-1) and Cardiotrophin-like Cytokine (CLC). Gp130 plays critical roles during development.
| Schlagworte: | Il6st, Membrane glycoprotein 130, Interleukin-6 signal transducer, Oncostatin-M receptor subunit alpha, Interleukin-6... |
| Ursprungsart: | mouse |
| MW: | 67.75 kD |
ab 403,00 €
SC144 (hydrochloride)
Artikelnummer: Cay29714-1
SC144 is an orally bioavailable gp130 inhibitor. It inhibits phosphorylation of STAT1, STAT3, and Akt induced by leukemia inhibitory factor (LIF) and IL-6, but not IFN-gamma, in OVCAR-8 ovarian cancer cells when used at a concentration of 20 µM. SC144 induces cell cycle arrest at the G0/G1 phase in MDA-MB-435 breast...
| Schlagworte: | 2-pyrazinecarboxylic acid, 2-(7-fluoropyrrolo[1,2-a]quinoxalin-4-yl)hydrazide, monohydrochloride |
| Anwendung: | gp130 inhibitor |
| CAS | 917497-70-2 |
| MW: | 358.8 D |
ab 49,00 €
Anti-CD130 / gp130 (azide free), clone B-R3
Artikelnummer: ARG23320.100
Protein function: Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates Janus kinases...
| Schlagworte: | Anti-gp130, Anti-IL6ST, Anti-CD130, Anti-IL-6RB, Anti-CDw130, Anti-IL-6R-beta, Anti-IL-6R subunit beta, Anti-Membrane... |
| Anwendung: | FC, ELISA, FA |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
658,00 €
Anti-CD130 / gp130 (azide free), clone B-S12
Artikelnummer: ARG23325.100
Protein function: Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates Janus kinases...
| Schlagworte: | Anti-gp130, Anti-IL6ST, Anti-CD130, Anti-IL-6RB, Anti-CDw130, Anti-IL-6R-beta, Anti-IL-6R subunit beta, Anti-Membrane... |
| Anwendung: | FC, IP, WB, FA |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
658,00 €
Anti-IL6ST/CD130
Artikelnummer: A304-929A
Protein function: Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates Janus kinases...
| Schlagworte: | Anti-IL6ST, Anti-CD130, Anti-gp130, Anti-CDw130, Anti-IL-6RB, Anti-IL-6R-beta, Anti-IL-6R subunit beta, Anti-Membrane... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
Human Gp130 - IL6ST ELISA Kit
Artikelnummer: KOA0185
Natural and recombinant human Sgp130. There is no detectable cross-reactivity with other relevant proteins. Protein function: Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST...
| Schlagworte: | IL6ST, gp130, CD130, IL-6RB, CDw130, IL-6R-beta, IL-6R subunit beta, Membrane glycoprotein 130, IL-6 receptor subunit... |
| Anwendung: | ELISA |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
1.030,00 €
Mouse Gp130 - IL6ST ELISA Kit
Artikelnummer: KOA0353
Natural and recombinant mouse Gp130. There is no detectable cross-reactivity with other relevant proteins. Protein function: Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST...
| Schlagworte: | gp130, Il6st, CD130, IL-6RB, IL-6R-beta, IL-6R subunit beta, Membrane glycoprotein 130, IL-6 receptor subunit beta,... |
| Anwendung: | ELISA |
| Wirt: | Mouse |
| Spezies-Reaktivität: | mouse |
1.030,00 €