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Zu "K05060" wurden 74 Artikel gefunden!
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Artikelnummer: Cay29714-1
SC144 is an orally bioavailable gp130 inhibitor. It inhibits phosphorylation of STAT1, STAT3, and Akt induced by leukemia inhibitory factor (LIF) and IL-6, but not IFN-gamma, in OVCAR-8 ovarian cancer cells when used at a concentration of 20 µM. SC144 induces cell cycle arrest at the G0/G1 phase in MDA-MB-435 breast...
Schlagworte: | 2-pyrazinecarboxylic acid, 2-(7-fluoropyrrolo[1,2-a]quinoxalin-4-yl)hydrazide, monohydrochloride |
Anwendung: | gp130 inhibitor |
CAS | 917497-70-2 |
MW: | 358.8 D |
ab 43,00 €
Artikelnummer: ARG23320.100
Protein function: Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates Janus kinases...
Schlagworte: | Anti-gp130, Anti-IL6ST, Anti-CD130, Anti-IL-6RB, Anti-CDw130, Anti-IL-6R-beta, Anti-IL-6R subunit beta, Anti-Membrane... |
Anwendung: | FC, ELISA, FA |
Wirt: | Mouse |
Spezies-Reaktivität: | human |
640,00 €
Artikelnummer: ARG23325.100
Protein function: Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates Janus kinases...
Schlagworte: | Anti-gp130, Anti-IL6ST, Anti-CD130, Anti-IL-6RB, Anti-CDw130, Anti-IL-6R-beta, Anti-IL-6R subunit beta, Anti-Membrane... |
Anwendung: | FC, IP, WB, FA |
Wirt: | Mouse |
Spezies-Reaktivität: | human |
640,00 €
Artikelnummer: ARG81316.96
Protein function: Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates Janus kinases...
Schlagworte: | gp130, IL6ST, CD130, IL-6RB, CDw130, IL-6R-beta, IL-6R subunit beta, Membrane glycoprotein 130, IL-6 receptor subunit... |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
1.056,00 €
Artikelnummer: A304-929A
Protein function: Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates Janus kinases...
Schlagworte: | Anti-IL6ST, Anti-CD130, Anti-gp130, Anti-CDw130, Anti-IL-6RB, Anti-IL-6R-beta, Anti-IL-6R subunit beta, Anti-Membrane... |
Anwendung: | WB, IP |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 164,00 €
Artikelnummer: KOA0185
Natural and recombinant human Sgp130. There is no detectable cross-reactivity with other relevant proteins. Protein function: Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST...
Schlagworte: | IL6ST, gp130, CD130, IL-6RB, CDw130, IL-6R-beta, IL-6R subunit beta, Membrane glycoprotein 130, IL-6 receptor subunit... |
Anwendung: | ELISA |
Wirt: | Human |
Spezies-Reaktivität: | human |
848,00 €
Artikelnummer: KOA0353
Natural and recombinant mouse Gp130. There is no detectable cross-reactivity with other relevant proteins. Protein function: Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST...
Schlagworte: | gp130, Il6st, CD130, IL-6RB, IL-6R-beta, IL-6R subunit beta, Membrane glycoprotein 130, IL-6 receptor subunit beta,... |
Anwendung: | ELISA |
Wirt: | Mouse |
Spezies-Reaktivität: | mouse |
848,00 €
Artikelnummer: DC-850.520.048
Diaclone ELISA Kits include pre-coated strip plates, biotinylated secondary antibody, standards, controls (where applicable), buffers, streptavidin-HRP, TMB, stop reagents, and a detailed procedure., Assay Range: 56.25-1800 pg/ml, Sensitivity: 15 pg/ml, Cross reaction: No cross reactivity with other human soluble...
Schlagworte: | Human CD130 ELISA Kit, gp130, CD130, gp130, IL-6RB, CDw130, IL-6R-beta, IL-6R subunit beta, Membrane glycoprotein 130,... |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 197,00 €
Artikelnummer: E-CL-M0338.96
Type: Sandwich. Detection Range: 31.25~2000pg/mL. Sensitivity: 18.75pg/mL. Tested Sample Types: Serum, Plasma, Cell supernatant. Test principle: This CLIA kit uses the Sandwich- CLIA principle. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to Mouse gp130 . Standards or...
Schlagworte: | Il6st, gp130, CD130, IL-6RB, IL-6R-beta, IL-6R subunit beta, Membrane glycoprotein 130, IL-6 receptor subunit beta,... |
Anwendung: | CLIA |
Spezies-Reaktivität: | mouse |
541,00 €
Artikelnummer: ARG81687.96
Protein function: Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates Janus kinases...
Schlagworte: | gp130, Il6st, CD130, IL-6RB, IL-6R-beta, IL-6R subunit beta, Membrane glycoprotein 130, IL-6 receptor subunit beta,... |
Anwendung: | ELISA |
Spezies-Reaktivität: | mouse |
1.048,00 €
Artikelnummer: E-AB-52510.120
The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent...
Schlagworte: | Anti-gp130, Anti-CD130, Anti-IL6ST, Anti-CDw130, Anti-IL-6RB, Anti-IL-6R-beta, Anti-IL-6R subunit beta, Anti-Membrane... |
Anwendung: | IHC, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 71,00 €
Artikelnummer: A700-114
Protein function: Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates Janus kinases...
Schlagworte: | Anti-IL6ST, Anti-gp130, Anti-CD130, Anti-IL-6RB, Anti-CDw130, Anti-IL-6R-beta, Anti-IL-6R subunit beta, Anti-Membrane... |
Anwendung: | WB, ICC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 172,00 €