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Zu "K05060" wurden 131 Artikel gefunden!
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NEU
Artikelnummer: SCC-EK0577
Gp130 (Glycoprotein 130) also known as IL6ST or CD130, is a transmembrane protein that is the founding member of the class of all cytokine receptors. The Gp130 gene is mapped to 5q11.2. Gp130 shows an apparent molecular mass of 130 kDa by SDS-PAGE. Gp130 is involved in the formation of high-affinity IL6-binding...
| Schlagworte: | mGp130-ELISA, Il6st, Membrane glycoprotein 130, Interleukin-6 signal transducer, Oncostatin-M receptor subunit alpha,... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
701,00 €
NEU
Artikelnummer: E-AN302757L.100
Protein function: Signal-transducing molecule (PubMed:2261637). The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates the...
| Schlagworte: | Anti-IL6ST, Anti-CDw130, Anti-Membrane glycoprotein 130, Anti-Interleukin-6 signal transducer, Anti-Oncostatin-M receptor... |
| Anwendung: | WB, IF, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human,mouse,rat |
ab 171,00 €
Artikelnummer: ELK-ELK10269MS.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse gp130. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse gp130. Next,...
| Schlagworte: | Il6st, Membrane glycoprotein 130, Interleukin-6 signal transducer, Oncostatin-M receptor subunit alpha, Interleukin-6... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 374,00 €
Artikelnummer: NSJ-F54230-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex....
| Schlagworte: | Anti-IL6ST, Anti-CDw130, Anti-Membrane glycoprotein 130, Anti-Interleukin-6 signal transducer, Anti-Interleukin-6 receptor... |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Artikelnummer: Cay43755-100
Glycoprotein 130 (gp130), also known as IL-6 signal transducer (IL6ST), is a single-pass type I membrane protein and shared signal transducing receptor for the IL-6 cytokine family. It is composed of an N-terminal immunoglobulin-like domain, two cytokine-binding domains, three fibronectin type III-like domains, a...
| Schlagworte: | gp130/IL6ST, CD130, CDw130, gp130, IL-6 Receptor Subunit beta, IL-6R Subunit beta, IL-6RB, Interleukin-6 Receptor Subunit... |
| Anwendung: | Active protein |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
ab 183,00 €
Artikelnummer: ARG81687.96
Protein function: Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates Janus kinases...
| Schlagworte: | gp130, Il6st, CD130, IL-6RB, IL-6R-beta, IL-6R subunit beta, Membrane glycoprotein 130, IL-6 receptor subunit beta,... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
1.118,00 €
Artikelnummer: ARG81316.96
Protein function: Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates Janus kinases...
| Schlagworte: | gp130, IL6ST, CD130, IL-6RB, CDw130, IL-6R-beta, IL-6R subunit beta, Membrane glycoprotein 130, IL-6 receptor subunit... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
1.118,00 €
Artikelnummer: Cay29714-1
SC144 is an orally bioavailable gp130 inhibitor. It inhibits phosphorylation of STAT1, STAT3, and Akt induced by leukemia inhibitory factor (LIF) and IL-6, but not IFN-gamma, in OVCAR-8 ovarian cancer cells when used at a concentration of 20 µM. SC144 induces cell cycle arrest at the G0/G1 phase in MDA-MB-435 breast...
| Schlagworte: | 2-pyrazinecarboxylic acid, 2-(7-fluoropyrrolo[1,2-a]quinoxalin-4-yl)hydrazide, monohydrochloride |
| Anwendung: | gp130 inhibitor |
| CAS | 917497-70-2 |
| MW: | 358.8 D |
ab 51,00 €
Artikelnummer: ARG23320.100
Protein function: Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates Janus kinases...
| Schlagworte: | Anti-gp130, Anti-IL6ST, Anti-CD130, Anti-IL-6RB, Anti-CDw130, Anti-IL-6R-beta, Anti-IL-6R subunit beta, Anti-Membrane... |
| Anwendung: | FC, ELISA, FA |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
658,00 €
Artikelnummer: ARG23325.100
Protein function: Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates Janus kinases...
| Schlagworte: | Anti-gp130, Anti-IL6ST, Anti-CD130, Anti-IL-6RB, Anti-CDw130, Anti-IL-6R-beta, Anti-IL-6R subunit beta, Anti-Membrane... |
| Anwendung: | FC, IP, WB, FA |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
658,00 €
Artikelnummer: A304-929A
Protein function: Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates Janus kinases...
| Schlagworte: | Anti-IL6ST, Anti-CD130, Anti-gp130, Anti-CDw130, Anti-IL-6RB, Anti-IL-6R-beta, Anti-IL-6R subunit beta, Anti-Membrane... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
Artikelnummer: KOA0185
Natural and recombinant human Sgp130. There is no detectable cross-reactivity with other relevant proteins. Protein function: Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST...
| Schlagworte: | IL6ST, gp130, CD130, IL-6RB, CDw130, IL-6R-beta, IL-6R subunit beta, Membrane glycoprotein 130, IL-6 receptor subunit... |
| Anwendung: | ELISA |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
1.030,00 €