- Suchergebnis für K05050
Cookie-Einstellungen
Diese Website benutzt Cookies, die für den technischen Betrieb der Website erforderlich sind und stets gesetzt werden. Andere Cookies, die den Komfort bei Benutzung dieser Website erhöhen, der Direktwerbung dienen oder die Interaktion mit anderen Websites und sozialen Netzwerken vereinfachen sollen, werden nur mit Ihrer Zustimmung gesetzt.
Konfiguration
Technisch erforderlich
Diese Cookies sind für die Grundfunktionen des Shops notwendig.
"Alle Cookies ablehnen" Cookie
"Alle Cookies annehmen" Cookie
Ausgewählter Shop
CSRF-Token
Cookie-Einstellungen
FACT-Finder Tracking
Individuelle Preise
Kundenspezifisches Caching
Session
Währungswechsel
Komfortfunktionen
Diese Cookies werden genutzt um das Einkaufserlebnis noch ansprechender zu gestalten, beispielsweise für die Wiedererkennung des Besuchers.
Facebook-Seite in der rechten Blog - Sidebar anzeigen
Merkzettel
Statistik & Tracking
Endgeräteerkennung
Kauf- und Surfverhalten mit Google Tag Manager
Partnerprogramm
Zu "K05050" wurden 34 Artikel gefunden!
Filter schließen
Filtern nach:
Für die Filterung wurden keine Ergebnisse gefunden!
Artikelnummer: Cay13336-10
CXCR2 (IL-8RB) is a seven-transmembrane G protein-coupled receptor whose physiological ligands include IL-8 (CXCL8) and growth related oncogene alpha (Gro-alpha, CXCL1). IL-8 and Gro-alpha are pro-inflammatory CXC chemokines that act as chemoattractants, especially for neutrophils, and promote angiogenesis. SB...
Schlagworte: | N-(2-bromophenyl)-N'-(2-hydroxy-4-nitrophenyl)-urea |
Anwendung: | CXCR2 antagonist |
CAS | 182498-32-4 |
MW: | 352.1 D |
ab 110,00 €
Artikelnummer: Cay20980-25
Danirixin is an antagonist of chemokine (C-X-C motif) receptor 2 (CXCR2, IC50 = 12.5 µM). It is selective for CXCR2 over CXCR1 (IC50 = 977 nM). Danirixin inhibits IL-8-induced calcium mobilization in CHO-K1 cells expressing human CXCR2 (pA2 = 7.52). It inhibits neutrophil surface expression of CD11b in isolated rat...
Schlagworte: | GSK1325756, GSK1325756B, N-[4-chloro-2-hydroxy-3-[(3S)-3-piperidinylsulfonyl]phenyl]-N'-(3-fluoro-2-methylphenyl)-urea |
Anwendung: | Antiinflammatory, Chemokine (C-X-C motif) receptor 2 antagonist |
CAS | 954126-98-8 |
MW: | 441.9 D |
ab 54,00 €
Artikelnummer: Cay21492-1
Reparixin is a non-competitive allosteric inhibitor of the activation of CXCR1 and CXCR2 chemokine receptors by IL-8 (IC50s = 1 and 100 nM, respectively). It blocks a range of activities related to IL-8 signaling, including leukocyte recruitment (IC50 = 1 nM) and other inflammatory responses, without affecting...
Schlagworte: | Repertaxin, (alphaR)-alpha-methyl-4-(2-methylpropyl)-N-(methylsulfonyl)benzeneacetamide, L-lysine |
Anwendung: | Noncompetitive allosteric CXCR1 / CXCR2 inhibitor |
CAS | 266359-93-7 |
MW: | 429.6 D |
ab 35,00 €
Artikelnummer: Cay17879-10
CXCR2 (IL-8RB) is a seven-transmembrane G protein-coupled receptor whose physiological ligands include IL-8 (CXCL8) and many other CXC chemokines involved in the trafficking and activation of inflammatory cells. It is involved in various inflammatory diseases, including chronic obstructive pulmonary disease,...
Schlagworte: | N-(2-bromophenyl)-N'-(4-cyano-1H-benzotriazol-7-yl)-urea |
Anwendung: | Allosteric, inverse CXCR2 agonist |
CAS | 211096-49-0 |
MW: | 357.2 D |
ab 130,00 €
Artikelnummer: Cay17359-1
Antileukinate is a synthetic hexapeptide with an acetylated amino terminus and an amidated carboxyl terminus that inhibits the binding of CXC chemokines to the chemokine receptor CXCR2. It inhibits IL-8 binding to neutrophils (Ki = 2.7-13 µM), prevents neutrophil chemotaxis and beta-glucuronidase release, and blocks...
Schlagworte: | N2-acetyl-L-arginyl-L-arginyl-L-tryptophyl-L-tryptophyl-L-cysteinyl-L-argininamide |
Anwendung: | CXCR2 antagonist |
CAS | 138559-60-1 |
MW: | 1003.2 D |
ab 161,00 €
Artikelnummer: Cay28297-5
AZD 5069 is an antagonist of chemokine receptor 2 (CXCR2, IC50 = 0.79 nM in a radioligand binding assay). It inhibits CXCL1-induced CD11b expression in and chemotaxis of isolated human neutrophils (pA2s = 6.9 and 9.1, respectively). AZD 5069 (3 and 10 µmol/kg) inhibits bronchoalveolar lavage fluid (BALF) neutrophil...
Schlagworte: | N-[2-[[(2,3-difluorophenyl)methyl]thio]-6-[(1R,2S)-2,3-dihydroxy-1-methylpropoxy]-4-pyrimidinyl]-1-azetidinesulfonamide |
Anwendung: | CXCR2 antagonist |
CAS | 878385-84-3 |
MW: | 476.5 D |
ab 44,00 €
Artikelnummer: ARG10829.50
Protein function: Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also...
Schlagworte: | Anti-CXCR2, Anti-IL8RB, Anti-CD182, Anti-CXCR-2, Anti-CXC-R2, Anti-CDw128b, Anti-IL-8R B, Anti-GRO/MGSA receptor,... |
Anwendung: | FC, ICC, IF, IHC (paraffin), IHC (frozen), IP, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
576,00 €
Artikelnummer: NSJ-R30204
0.5mg/ml if reconstituted with 0.2ml sterile DI water. CXCR2 is a receptor for Interleukin 8, which is a powerful neutrophil chemotactic factor. It is a member of the GPCR family(subfamily, chemokine). Binding of IL8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that...
Schlagworte: | Anti-CD182, Anti-CXCR2, Anti-IL8RB, Anti-CXCR-2, Anti-CXC-R2, Anti-IL-8R B, Anti-CDw128b, Anti-GRO/MGSA receptor,... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, rat |
755,00 €
Artikelnummer: NSJ-R33768-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Chemokine (C-X-C motif) receptor 2, CD128 Protein function: Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of...
Schlagworte: | Anti-CD182, Anti-IL8RB, Anti-CXCR2, Anti-CXC-R2, Anti-CXCR-2, Anti-CDw128b, Anti-IL-8R B, Anti-GRO/MGSA receptor,... |
Anwendung: | WB, ELISA (peptide) |
Wirt: | Goat |
Spezies-Reaktivität: | mouse |
755,00 €
Artikelnummer: G-HUES03382.96
ELISA Type: Sandwich. Sensitivity: 0.469ng/mL. Range: 0.781--50ng/mL. Protein function: Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a...
Schlagworte: | IL8RB, CD182, CXCR2, CXCR-2, CXC-R2, IL-8R B, CDw128b, GRO/MGSA receptor, IL-8 receptor type 2, C-X-C chemokine receptor... |
Anwendung: | Sandwich ELISA |
Spezies-Reaktivität: | human |
641,00 €
Artikelnummer: G-MOES01751.96
ELISA Type: Sandwich. Sensitivity: 18.75pg/mL. Range: 31.25--2000pg/mL. Protein function: Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a...
Schlagworte: | Cxcr2, CD182, CXCR-2, Cmkar2, CXC-R2, IL-8R B, GRO/MGSA receptor, C-X-C chemokine receptor type 2, High affinity... |
Anwendung: | Sandwich ELISA |
Spezies-Reaktivität: | mouse |
694,00 €
Artikelnummer: Cay32869-1
SB-332235 is an antagonist of chemokine (C-X-C motif) receptor 2 (CXCR2, IC50 = 9.3 nM in CHO cell membranes expressing the recombinant human receptor). It is selective for CXCR2 over CXCR1 (IC50 = 9,633 nM). SB-332235 (10 ng/ml) inhibits migration of isolated human peripheral blood monocytes induced by chemokine...
Schlagworte: | 6-chloro-3-[[[(2,3-dichlorophenyl)amino]carbonyl]amino]-2-hydroxy-benzenesulfonamide |
Anwendung: | CXCR2 antagonist |
CAS | 276702-15-9 |
MW: | 410.7 D |
ab 60,00 €