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GBR 12783 (hydrochloride)
GBR 12783 (hydrochloride)

Artikelnummer: Cay35662-1

GBR 12783 is a dopamine uptake inhibitor (IC50 = 13 nM in rat striatal synaptosomes). It is selective for inhibition of dopamine uptake over norepinephrine or serotonin (5-HT) uptake (IC50s = 230 and 1,100 nM in rat hypothalamic and striatal synaptosomes, respectively). GBR 12783 (10 mg/kg, i.p.) improves learning...
Schlagworte: Lu 2-098, MW-486, 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenyl-2-propen-1-yl)-piperazine, dihydrochloride
Anwendung: Dopamine uptake inhibitor
CAS 67469-75-4
MW: 485.5 D
ab 34,00 €
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BTS-54-505 (hydrochloride)
BTS-54-505 (hydrochloride)

Artikelnummer: Cay39828-1

BTS-54-505 is an active metabolite of sibutramine. It inhibits norepinephrine, serotonin (5-HT), and dopamine uptake in rat cortical synaptosomes (IC50s = 0.066, 5.1, and 0.61 µM, respectively). In vivo, BTS-54-505 prevents reserpine-induced ptosis in rats (ED50 = 3.7 mg/kg) and decreases immobility in the Porsolt...
Schlagworte: 1-(4-chlorophenyl)-alpha-(2-methylpropyl)-cyclobutanemethanamine, monohydrochloride
Anwendung: Active sibutramine metabolite
CAS 84484-78-6
MW: 288.3 D
ab 35,00 €
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Human DAT (Dopamine Transporter) ELISA Kit
Human DAT (Dopamine Transporter) ELISA Kit

Artikelnummer: ELK-ELK3484.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human DAT. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human DAT. Next,...
Schlagworte: DAT, DAT1, SLC6A3, DA transporter, Solute carrier family 6 member 3, Sodium-dependent dopamine transporter
Anwendung: ELISA
Spezies-Reaktivität: human
ab 365,00 €
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Mouse DAT (Dopamine Transporter) ELISA Kit
Mouse DAT (Dopamine Transporter) ELISA Kit

Artikelnummer: ELK-ELK5272.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse DAT. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse DAT. Next,...
Schlagworte: Dat, DAT, Slc6a3, DA transporter, Solute carrier family 6 member 3, Sodium-dependent dopamine transporter
Anwendung: ELISA
Spezies-Reaktivität: mouse
ab 365,00 €
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Rat DAT (Dopamine Transporter) ELISA Kit
Rat DAT (Dopamine Transporter) ELISA Kit

Artikelnummer: ELK-ELK5654.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat DAT. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat DAT. Next, Avidin...
Schlagworte: DAT, Slc6a3, DA transporter, Solute carrier family 6 member 3, Sodium-dependent dopamine transporter
Anwendung: ELISA
Spezies-Reaktivität: rat
ab 365,00 €
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Benztropine mesylate
Benztropine mesylate

Artikelnummer: LKT-B1955.1

Benztropine is an inhibitor of the dopamine transporter (DAT), it potentiates dopamine overflow in rat brain slices.
Anwendung: Muscarinic cholinergic receptor antagonist, Dopamine transporter inhibitor
CAS 132-17-2
MW: 403.53 D
ab 90,00 €
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GBR 13069 (hydrochloride)
GBR 13069 (hydrochloride)

Artikelnummer: Cay38903-10

GBR 13069 is a dopamine uptake inhibitor. It selectively inhibits dopamine uptake over norepinephrine uptake in rat occipital cortex slices (IC50s = 40 and 800 nM, respectively). GBR 13069 (2.5, 5, and 10 mg/kg) induces ipsilateral rotation and increases locomotion in rats. It also prevents 2'-CH3-MPTP-induced...
Schlagworte: 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenyl-2-propen-1-yl)-piperazine, dihydrochloride
Anwendung: Dopamine uptake inhibitor
CAS 67469-45-8
MW: 521.5 D
ab 109,00 €
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Sibutramine (hydrochloride)
Sibutramine (hydrochloride)

Artikelnummer: Cay14476-5

Sibutramine (hydrochloride) (Cay-14476) is an analytical reference standard categorized as a phenylethylamine. It inhibits reuptake of serotonin (Cay-14332) and norepinephrine (Cay-16673) via the respective transporters. Sibutramine can be detected in plasma and urine. Formulations containing sibutramine were...
Schlagworte: BTS-54524, 1-(4-chlorophenyl)-N,N-dimethyl-alpha-(2-methylpropyl)-cyclobutanemethanamine, monohydrochloride
Anwendung: Analytical reference standard, Phenylethylamine, Serotonin/norepinephrine reuptake inhibitor (SNRI)
CAS 84485-00-7
MW: 316.3 D
ab 125,00 €
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(±)-threo-3,4-Dichloromethylphenidate (hydrochloride)
(±)-threo-3,4-Dichloromethylphenidate (hydrochloride)

Artikelnummer: Cay18588-1

(±)-threo-3,4-Dichloromethylphenidate (hydrochloride) (Cay-18588) is an analytical reference material that is structurally categorized as an amphetamine. Its threo-diastereomer, 3,4-CTMP, can inhibit dopamine uptake through the dopamine transporter with an IC50 value of 65 nM in rat striatal tissue. This product is...
Schlagworte: (alphaR,2R)-rel-alpha-(3,4-dichlorophenyl)-2-piperidineacetic acid, methyl ester, monohydrochloride
Anwendung: Analytical reference material, Amphetamine, Dopamine uptake inhibitor
CAS 214149-42-5
MW: 338.7 D
ab 98,00 €
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S,S-hydroxy Bupropion (hydrochloride)
S,S-hydroxy Bupropion (hydrochloride)

Artikelnummer: Cay35718-1

S,S-hydroxy Bupropion is an active metabolite of the antidepressant bupropion. It is formed from bupropion by the cytochrome P450 (CYP) isoform CYP2B6. S,S-hydroxy Bupropion inhibits dopamine and norepinephrine but not serotonin (5-HT) reuptake in HEK293 cells expressing the human transporters (IC50s = 0.63, 0.241,...
Schlagworte: BUPOH, BW 306U, GW 353162A, Radafaxine, (2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethyl-2-morpholinol, monohydrochloride
Anwendung: Bupropion active metabolite, NDRI
CAS 106083-71-0
MW: 292.2 D
ab 39,00 €
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Anti-Dopamine Transporter, C-terminal
Anti-Dopamine Transporter, C-terminal

Artikelnummer: ARG52263.50

Protein function: Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals. [The UniProt Consortium]
Schlagworte: Anti-DAT, Anti-DAT1, Anti-SLC6A3, Anti-DA transporter, Anti-Solute carrier family 6 member 3, Anti-Sodium-dependent...
Anwendung: IHC, WB
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, primates
592,00 €
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Anti-phospho-Dopamine Transporter (Thr53)
Anti-phospho-Dopamine Transporter (Thr53)

Artikelnummer: ARG52265.50

Protein function: Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals. [The UniProt Consortium]
Schlagworte: Anti-phospho-DAT, Anti-phospho-Slc6a3, Anti-phospho-DA transporter, Anti-phospho-Solute carrier family 6 member 3,...
Anwendung: IHC, WB
Wirt: Rabbit
Spezies-Reaktivität: rat
592,00 €
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