Zu "K05034" wurden 31 Artikel gefunden!
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Anti-GABA Transporter 1 / GAT-1 / SLC6A1
Artikelnummer: NSJ-RQ8735
0.5mg/ml if reconstituted with 0.2ml sterile DI water. GABA transporter 1 (GAT1), also known as sodium- and chloride-dependent GABA transporter 1, is a protein that in humans is encoded by the SLC6A1 gene. GABA Transporter 1 uses Na+ and Cl- to create a gradient, which removes or adds GABA to extracellular spaces in...
| Schlagworte: | Anti-SLC6A1, Anti-Solute carrier family 6 member 1, Anti-Sodium- and chloride-dependent GABA transporter 1, GABA... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
SKF 89976A (hydrochloride)
Artikelnummer: Cay42449-10
SKF 89976A is an inhibitor of GABA transporter 1 (GAT1, IC50s = 0. and 0. µM for the human and rat transporters, respectively). It is selective for GAT1 over rat GAT2, human GAT3, and human betaine/GABA transporter 3 (BGT3, IC50s = 550, 944, and 7,210 µM, respectively). SKF 89976A inhibits GABA uptake in rat...
| Schlagworte: | 1-(4,4-diphenyl-3-buten-1-yl)-3-piperidinecarboxylic acid, monohydrochloride |
| Anwendung: | GAT1 (GABA transporter 1) inhibitor |
| CAS | 85375-15-1 |
| MW: | 371.9 D |
ab 60,00 €
Tiagabine (hydrochloride)
Artikelnummer: Cay22926-10
Tiagabine is an inhibitor of GABA transporter 1 (GAT-1, IC50 = 49 nM for GAT-1 expressed in CHO cells). It inhibits seizures induced by DMCM in mice (ED50 = 1.2 mg/kg, i.p.). Tiagabine reduces allodynia in a rodent model of neuropathic pain when used at a dose of 72.8 µmol/kg, and it acts synergistically with...
| Schlagworte: | ABT-569, (3R)-1-[4,4-bis(3-methyl-2-thienyl)-3-buten-1-yl]-3-piperidinecarboxylic acid, monohydrochloride |
| Anwendung: | GABA mimetic antiepileptic |
| CAS | 145821-59-6 |
| MW: | 412 D |
ab 49,00 €
Anti-GABA Transporter 1 (GAT1)
Artikelnummer: 612-401-D56
Anti-GABA Transporter 1 antibody is directed against rat GABA Transporter 1. GABA Transporter 1 antibodies are affinity purified from monospecific antiserum by immunoaffinity purification. Reactivity is expected from the following species based on 100% sequence homology: mouse. Protein function: Terminates the...
| Schlagworte: | Anti-Gabt1, Anti-GAT-1, Anti-Slc6a1, Anti-Solute carrier family 6 member 1, Anti-Sodium- and chloride-dependent GABA... |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | rat, mouse |
877,00 €
Anti-GAT-1 / GABA Transporter 1 / SLC6A1 (N-Terminal Region)
Artikelnummer: NSJ-R32967
0.5mg/ml if reconstituted with 0.2ml sterile DI water. GABA transporter 1 (GAT1), also known as sodium- and chloride-dependent GABA transporter 1, is a protein that in humans is encoded by the SLC6A1 gene. GABA Transporter 1 uses Na+ and Cl- to create a gradient, which removes or adds GABA to extracellular spaces in...
| Schlagworte: | Anti-GAT-1, Anti-SLC6A1, Anti-GABATR, Anti-Solute carrier family 6 member 1, Anti-Sodium- and chloride-dependent GABA... |
| Anwendung: | WB, IHC (paraffin), IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
NNC-711 (hydrochloride)
Artikelnummer: Cay29687-1
NNC-711 is an inhibitor of GABA transporter 1 (GAT-1, IC50 = 0.04 µM for the human transporter). It is selective for GAT-1 over human GAT-3 and BGT-3 (IC50s = 1,700 and 622 µM, respectively), rat GAT-2 (IC50 = 171 µM), and a panel of 21 receptors and ion channels (IC50s = >50 µM for all) in radioligand binding...
| Schlagworte: | NNC 05-711, NO-711, 1-[2-[[(diphenylmethylene)amino]oxy]ethyl]-1,2,5,6-tetrahydro-3-pyridinecarboxylic acid,... |
| Anwendung: | GAT-1 inhibitor |
| CAS | 145645-62-1 |
| MW: | 386.9 D |
ab 49,00 €
Tiagabine-d6 (hydrochloride)
Artikelnummer: Cay30766-1
Tiagabine-d6 is intended for use as an internal standard for the quantification of tiagabine (Cay-22926) by GC- or LC-MS. Tiagabine is an inhibitor of GABA transporter 1 (GAT-1, IC50 = 49 nM for GAT-1 expressed in CHO cells). It inhibits seizures induced by DMCM in mice (ED50 = 1.2 mg/kg, i.p.). Tiagabine reduces...
| Schlagworte: | (3R)-1-[4,4-bis(3-methyl-d3-2-thienyl)-3-buten-1-yl]-3-piperidinecarboxylic acid, monohydrochloride |
| Anwendung: | GC-MS, LC-MS, internal standard, quantification, GABA mimetic antiepileptic |
| CAS | 1217808-68-8 |
| MW: | 418 D |
ab 166,00 €
Anti-SLC6A1
Artikelnummer: ATA-HPA013341.100
Protein function: Terminates the action of GABA by its high affinity sodium- dependent reuptake into presynaptic terminals. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 98% and to rat: 98%
| Schlagworte: | Anti-GAT-1, Anti-SLC6A1, Anti-GABATR, Anti-Solute carrier family 6 member 1, Anti-Sodium- and chloride-dependent GABA... |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 246,00 €
Nipecotic Acid
Artikelnummer: Cay36126-100
Nipecotic acid is an inhibitor of GABA transporters (GAT, IC50s = 2.6, 310, 29, and 16 µM for mouse GAT-1, GAT-2, GAT-3, and GAT-4, respectively). It does not bind GABAA or GABAB receptors (IC50s = >100 µM for both) but does bind the adenosine A3 receptor (IC50 = 0.01 µM). Nipecotic acid inhibits GABA uptake in...
| Schlagworte: | (±)-Nipecotic Acid, (R,S)-Nipecotic Acid, 3-Piperidine Carboxylic Acid, DL-Piperidine 3-Carboxylic Acid,... |
| Anwendung: | GAT inhibitor |
| CAS | 498-95-3 |
| MW: | 129.2 D |
ab 44,00 €
Anti-GABA Transporter 1
Artikelnummer: ELK-EA290.100
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Protein function: Mediates transport of gamma-aminobutyric acid (GABA) together with sodium and chloride and is responsible for...
| Schlagworte: | Anti-GAT-1, Anti-SLC6A1, Anti-GABATR, Anti-Solute carrier family 6 member 1, Anti-Sodium- and chloride-dependent GABA... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
290,00 €
Anti-SLC6A1
Artikelnummer: CSB-PA337896.100
Host Species: Rabbit. Isotype: IgG. Buffer: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific...
| Schlagworte: | Anti-GAT-1, Anti-SLC6A1, Anti-GABATR, Anti-Solute carrier family 6 member 1, Anti-Sodium- and chloride-dependent GABA... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Anti-SLC6A1
Artikelnummer: CSB-PA778804.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SLC6A1. Antigen Species: Human
| Schlagworte: | Anti-GAT-1, Anti-SLC6A1, Anti-GABATR, Anti-Solute carrier family 6 member 1, Anti-Sodium- and chloride-dependent GABA... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €