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Zu "K05034" wurden 30 Artikel gefunden!
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Artikelnummer: TGM-T7000-100mg
Description: Tiagabine hydrochloride (NO050328 hydrochloride) is the hydrochloride salt form of tiagabine, a nipecotic acid derivative with anticonvulsant property. A selective gamma-aminobutyric acid (GABA) reuptake inhibitor. Target: GABA Receptor. Smiles: Cl.Cc1ccsc1\C(=C\CCN1CCC[C@H](C1)C(O)=O)c1sccc1C....
Schlagworte: | TGB hydrochloride, NO050328 hydrochloride, Gabitril, Gabitril hydrochloride, NO328 hydrochloride |
Anwendung: | Targets solute carrier family 6 (neurotransmitter transporter, GABA) member 1 (SLC6A1, GAT1) |
CAS | 145821-59-6 |
MW: | 412.01 D |
ab 46,00 €
Artikelnummer: TGM-T71206-1mg
Description: Tiagabine-d6 is intended for use as an internal standard for the quantification of tiagabine by GC- or LC-MS. Tiagabine is an inhibitor of GABA transporter 1. It inhibits seizures induced by DMCM in mice. Tiagabine reduces allodynia in a rodent model of neuropathic pain when used at a dose of 72.8...
Anwendung: | GC-MS, LC-MS, internal standard, quantification, GABA mimetic antiepileptic |
CAS | 1217808-68-8 |
MW: | 418.0396 D |
ab 276,00 €
Artikelnummer: CSB-PA337896.100
Host Species: Rabbit. Isotype: IgG. Buffer: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific...
Schlagworte: | Anti-GAT-1, Anti-SLC6A1, Anti-GABATR, Anti-Solute carrier family 6 member 1, Anti-Sodium- and chloride-dependent GABA... |
Anwendung: | ELISA, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Artikelnummer: CSB-PA778804.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SLC6A1. Antigen Species: Human
Schlagworte: | Anti-GAT-1, Anti-SLC6A1, Anti-GABATR, Anti-Solute carrier family 6 member 1, Anti-Sodium- and chloride-dependent GABA... |
Anwendung: | ELISA, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
Artikelnummer: CSB-PA801720.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen....
Schlagworte: | Anti-GAT-1, Anti-SLC6A1, Anti-GABATR, Anti-Solute carrier family 6 member 1, Anti-Sodium- and chloride-dependent GABA... |
Anwendung: | ELISA, WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Artikelnummer: CSB-PA935504.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SLC6A1. Antigen Species: Human
Schlagworte: | Anti-GAT-1, Anti-SLC6A1, Anti-GABATR, Anti-Solute carrier family 6 member 1, Anti-Sodium- and chloride-dependent GABA... |
Anwendung: | ELISA, WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
Artikelnummer: Cay22926-10
Tiagabine is an inhibitor of GABA transporter 1 (GAT-1, IC50 = 49 nM for GAT-1 expressed in CHO cells). It inhibits seizures induced by DMCM in mice (ED50 = 1.2 mg/kg, i.p.). Tiagabine reduces allodynia in a rodent model of neuropathic pain when used at a dose of 72.8 µmol/kg, and it acts synergistically with...
Schlagworte: | ABT-569, (3R)-1-[4,4-bis(3-methyl-2-thienyl)-3-buten-1-yl]-3-piperidinecarboxylic acid, monohydrochloride |
Anwendung: | GABA mimetic antiepileptic |
CAS | 145821-59-6 |
MW: | 412 D |
ab 44,00 €
Artikelnummer: 612-401-D56
Anti-GABA Transporter 1 antibody is directed against rat GABA Transporter 1. GABA Transporter 1 antibodies are affinity purified from monospecific antiserum by immunoaffinity purification. Reactivity is expected from the following species based on 100% sequence homology: mouse. Protein function: Terminates the...
Schlagworte: | Anti-Gabt1, Anti-GAT-1, Anti-Slc6a1, Anti-Solute carrier family 6 member 1, Anti-Sodium- and chloride-dependent GABA... |
Anwendung: | IHC, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | rat, mouse |
863,00 €
Artikelnummer: NSJ-R30811
0.5mg/ml if reconstituted with 0.2ml sterile DI water. SLC6A1 (Solute Carrier family 6(Neurotransmitter transporter, Gaba), Member 1), also called GABATR, GABATHG and GAT-1, encodes a gamma-aminobutyric acid (GABA) transporter, which removes GABA from the synaptic cleft. Zomot et al.(2007) showed that introduction...
Schlagworte: | Anti-GAT-1, Anti-SLC6A1, Anti-GABATR, Anti-Solute carrier family 6 member 1, Anti-Sodium- and chloride-dependent GABA... |
Anwendung: | WB, IHC (paraffin) |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
772,00 €
Artikelnummer: NSJ-R32967
0.5mg/ml if reconstituted with 0.2ml sterile DI water. GABA transporter 1 (GAT1), also known as sodium- and chloride-dependent GABA transporter 1, is a protein that in humans is encoded by the SLC6A1 gene. GABA Transporter 1 uses Na+ and Cl- to create a gradient, which removes or adds GABA to extracellular spaces in...
Schlagworte: | Anti-GAT-1, Anti-SLC6A1, Anti-GABATR, Anti-Solute carrier family 6 member 1, Anti-Sodium- and chloride-dependent GABA... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | mouse, rat |
772,00 €
Artikelnummer: Cay29687-1
NNC-711 is an inhibitor of GABA transporter 1 (GAT-1, IC50 = 0.04 µM for the human transporter). It is selective for GAT-1 over human GAT-3 and BGT-3 (IC50s = 1,700 and 622 µM, respectively), rat GAT-2 (IC50 = 171 µM), and a panel of 21 receptors and ion channels (IC50s = >50 µM for all) in radioligand binding...
Schlagworte: | NNC 05-711, NO-711, 1-[2-[[(diphenylmethylene)amino]oxy]ethyl]-1,2,5,6-tetrahydro-3-pyridinecarboxylic acid,... |
Anwendung: | GAT-1 inhibitor |
CAS | 145645-62-1 |
MW: | 386.9 D |
ab 44,00 €
Artikelnummer: E-AB-66423.120
The protein encoded by this gene is a gamma-aminobutyric acid (GABA) transporter that localizes to the plasma membrane. The encoded protein removes GABA from the synaptic cleft, restoring it to presynaptic terminals. Protein function: Terminates the action of GABA by its high affinity sodium- dependent reuptake into...
Schlagworte: | Anti-GAT-1, Anti-GABATR, Anti-SLC6A1, Anti-Solute carrier family 6 member 1, Anti-Sodium- and chloride-dependent GABA... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 243,00 €