Zu "K05033" wurden 24 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
PNU 37883 (hydrochloride)
Artikelnummer: Cay44821-1
A KATP channel inhibitor, inhibits SUR2B/Kir6.2 and SUR2B/Kir6.1 (IC50s = 15.2 and 6 µM, respectively) and SUR1/Kir6.2 and SUR2A/Kir6.2 to a lesser extent at 100 µM, inhibits pinacidil-, levcromakalim-, or P1075-induced relaxation of isolated rat middle meningeal arteries at 0.1 and 0.3 µM, increases kallikrein...
| Schlagworte: | PNU 37883A, U-37883A, N-cyclohexyl-N'-tricyclo[3.3.1.1 ]dec-1-yl-4-morpholinecarboximidamide, monohydrochloride |
| Anwendung: | K-ATP channel inhibitor |
| CAS | 57568-80-6 |
| MW: | 381.99 D |
ab 48,00 €
VU0542270
Artikelnummer: Cay43074-10
VU0542270 is an inhibitor of sulfonylurea receptor 2B (SUR2B) linked to ATP-sensitive potassium channel Kir6. (SUR2B/Kir6.1, IC50 = 0. µM). It is selective for SUR2B/Kir6. over ten other inward-rectifier potassium channels (Kirs, IC50s = >30 µM for all). VU0542270 (10 or 100 µM) induces constriction in isolated...
| Schlagworte: | N-[[4-methyl-2-(2-thienyl)-5-thiazolyl]methyl]-N'-2-thienyl-urea |
| Anwendung: | SUR2B/Kir6.1 inhibitor |
| CAS | 1396814-79-1 |
| MW: | 335.46 D |
ab 236,00 €
P1075
Artikelnummer: Cay21849-5
P1075 is a potent activator of sulfonylurea receptor 2-associated ATP-sensitive potassium channels (SUR2-Kir6) with an EC50 value of 45 nM for SUR2B-Kir6 channel activation. It is highly selective for SUR2 over SUR1 isoforms (IC50s = 9-46 nM and 1.02 mM, respectively, in a radioligand binding assay). P1075 increases...
| Schlagworte: | N-cyano-N'-(1,1-dimethylpropyl)-N''-3-pyridinyl-guanidine |
| Anwendung: | Kir6 channel opener |
| CAS | 60559-98-0 |
| MW: | 231.3 D |
ab 73,00 €
Nicorandil
Artikelnummer: Cay18460-50
Nicorandil is an activator of sulfonylurea receptor 2B (SUR2B) linked to ATP-sensitive potassium channel Kir6.2 (EC50 = ~10 µM) and a nitric oxide (NO) donor. It is selective for SUR2B/Kir6.2 over the SUR2A/Kir6.2 channel (EC50 = >500 µM). Nicorandil activates soluble guanylate cyclase in a cell-free assay and...
| Schlagworte: | 2-Nicotinamidoethyl nitrate, SG-75, N-[2-(nitrooxy)ethyl]-3-pyridinecarboxamide |
| Anwendung: | ATP-sensitive potassium channel (SUR1/Kir6.2) opener, nitric oxide donor |
| CAS | 65141-46-0 |
| MW: | 211.2 D |
ab 49,00 €
Repaglinide
Artikelnummer: LKT-R1860.250
Used in treatment of type II diabetes.
| Schlagworte: | Sulfonylurea receptor 1/2 agonist |
| Anwendung: | Antidiabetic [oral hypoglycemic agent] |
| CAS | 135062-02-1 |
| MW: | 452,59 D |
ab 254,00 €
Anti-ABCC9
Artikelnummer: E-AB-16894.120
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a...
| Schlagworte: | Anti-SUR2, Anti-ABCC9, Anti-Sulfonylurea receptor 2, Anti-ATP-binding cassette sub-family C member 9, ABCC9 Polyclonal... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
PPQ-102
Artikelnummer: Cay16275-50
The cystic fibrosis (CF) gene encodes a cAMP-regulated chloride channel, the CF transmembrane conductance regulator (CFTR). PPQ-102 is a cell-permeable pyrimido-pyrrolo-quinoxalinedione that reversibly inhibits CFTR chloride channels with an IC50 value of 90 nM. At 0.5-5 µM, PPQ-102 has been used to reduce the size...
| Schlagworte: | CFTR Inhibitor IV, Cystic Fibrosis Transmembrane Conductance Regulator Inhibitor IV,... |
| Anwendung: | CFTR inhibitor |
| CAS | 931706-15-9 |
| MW: | 438.5 D |
ab 134,00 €
Human ABCC9 (ATP Binding Cassette Transporter C9) ELISA Kit
Artikelnummer: ELK-ELK4728.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human ABCC9. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human ABCC9. Next,...
| Schlagworte: | ABCC9, Sulfonylurea receptor 2, ATP-binding cassette sub-family C member 9 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 374,00 €
Anti-ABCC9
Artikelnummer: CSB-PA043862.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: ABCC9. Antigen Species: Human
| Schlagworte: | Anti-SUR2, Anti-ABCC9, Anti-Sulfonylurea receptor 2, Anti-ATP-binding cassette sub-family C member 9, ABC37 antibody,... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
Anti-ABCC9
Artikelnummer: CSB-PA920347.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: ABCC9. Antigen Species: Human
| Schlagworte: | Anti-SUR2, Anti-ABCC9, Anti-Sulfonylurea receptor 2, Anti-ATP-binding cassette sub-family C member 9, ABC37 antibody,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
P-1075
Artikelnummer: TGM-T16420-100mg
Description: P-1075 is a potent sulfonylurea receptor 2-associated ATP-sensitive potassium channels (SUR2-KIR6) activator (EC50 = 45 nM). P-1075 opens opens mitoKATP channels and may be cardioprotective. Target: Potassium Channel. Smiles: CCC(C)(C)N\C(NC#N)=N\c1cccnc1. References: Schwanstecher M, et al. Potassium...
| Anwendung: | Kir6 channel opener |
| CAS | 60559-98-0 |
| MW: | 231.3 D |
ab 52,00 €
ABCC9 (human), recombinant protein
Artikelnummer: ABS-PP-5648-L.100
Protein function: Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with KCNJ11. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation. [The UniProt Consortium]
| Schlagworte: | ATP-binding cassette sub-family C member 9, Sulfonylurea receptor 2, Recombinant Human ABCC9 Protein |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 43.5 kD |
ab 115,00 €