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Lubiprostone
Lubiprostone

Artikelnummer: TGM-T6307-100mg

Description: Lubiprostone (RU-0211), an activator of ClC-2 chloride channels, is used in the therapy of idiopathic chronic constipation. Target: Chloride channel. Smiles: CCCCC(F)(F)C(=O)CC[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O. References: Bijvelds MJ, et al. Gastroenterology, 2009, 137(3), 976-1985.
Schlagworte: RU-0211, SPI-0211
Anwendung: ClC-2 activator
CAS 136790-76-6
MW: 390.46 D
ab 46,00 €
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Anti-CLCN2, Internal
Anti-CLCN2, Internal

Artikelnummer: ARG65190.100

Protein function: Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. [The UniProt Consortium]
Schlagworte: Anti-CLCN2, Anti-ClC-2, Anti-Chloride channel protein 2
Anwendung: ELISA, WB
Wirt: Goat
Spezies-Reaktivität: human
822,00 €
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Anti-CLCN2
Anti-CLCN2

Artikelnummer: NSJ-R35412-100UG

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Chloride channel 2 Protein function: Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume, membrane potential stabilization, signal...
Schlagworte: Anti-CLCN2, Anti-ClC-2, Anti-Chloride channel protein 2, CLCN2 Antibody
Anwendung: WB, ELISA (peptide)
Wirt: Goat
Spezies-Reaktivität: human
790,00 €
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Lubiprostone
Lubiprostone

Artikelnummer: Cay10010487-10

Lubiprostone is an activator of chloride channel protein 2 (ClC-2) and a bicyclic derivative of prostaglandin E1 (PGE1, Cay-13010). It induces chloride currents in HEK293 cells expressing recombinant human ClC-2 (EC50 = ~17 nM), but not CFTR, chloride channels. Lubiprostone (1 µM) induces short-circuit currents, a...
Schlagworte: RU-0211, SPI-0211, 16,16-difluoro-11alpha-hydroxy-9,15-dioxo-prostan-1-oic acid
Anwendung: ClC-2 activator
CAS 136790-76-6
MW: 390.5 D
ab 85,00 €
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Anti-CLCN2
Anti-CLCN2

Artikelnummer: ATA-HPA014545.100

Protein function: Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. Involved in the regulation of aldosterone production. The opening of CLCN2 channels at...
Schlagworte: Anti-CLCN2, Anti-ClC-2, Anti-Chloride channel protein 2
Anwendung: ICC, IHC
Wirt: Rabbit
Spezies-Reaktivität: human
ab 358,00 €
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Anti-CLCN2
Anti-CLCN2

Artikelnummer: ATA-HPA024108.100

Protein function: Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. Involved in the regulation of aldosterone production. The opening of CLCN2 channels at...
Schlagworte: Anti-CLCN2, Anti-ClC-2, Anti-Chloride channel protein 2
Anwendung: IHC
Wirt: Rabbit
Spezies-Reaktivität: human
ab 358,00 €
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NEU
Anti-clh-3
Anti-clh-3

Artikelnummer: CSB-PA190466XA01CXY.2

Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
Schlagworte: Anti-Chloride channel protein clh-3, clh-3 Antibody
Anwendung: ELISA, WB
Wirt: Rabbit
Spezies-Reaktivität: Caenorhabditis elegans
ab 1.529,00 €
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NEU
Anti-Clcn2
Anti-Clcn2

Artikelnummer: CSB-PA005481XA01RA.2

Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
Schlagworte: Anti-Clcn2, Anti-ClC-2, Anti-Chloride channel protein 2, Clcn2 Antibody
Anwendung: ELISA, WB
Wirt: Rabbit
Spezies-Reaktivität: Rattus norvegicus (Rat)
ab 1.529,00 €
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NEU
Anti-ClC-a
Anti-ClC-a

Artikelnummer: CSB-PA894220XA01DLU.2

Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
Schlagworte: Anti-ClC-2, Anti-ClC-a, Anti-DmClC-2, Anti-CG31116, Anti-Chloride channel-a, Anti-Chloride channel protein 2, ClC-a Antibody
Anwendung: ELISA, WB
Wirt: Rabbit
Spezies-Reaktivität: Drosophila melanogaster (Fruit fly)
ab 1.529,00 €
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NEU
Nanodisc Human CLCN2 Protein
Nanodisc Human CLCN2 Protein

Artikelnummer: G-HDFP527.10

Protein function: Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. Involved in the regulation of aldosterone production. The opening of CLCN2 channels at...
Schlagworte: ClC-2, CLCN2, Chloride channel protein 2
Exprimiert in: Human cells
Ursprungsart: human
1.486,00 €
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NEU
Nanodisc Human CLCN2-Strep Protein
Nanodisc Human CLCN2-Strep Protein

Artikelnummer: G-HDFP1242.10

Protein function: Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. Involved in the regulation of aldosterone production. The opening of CLCN2 channels at...
Schlagworte: ClC-2, CLCN2, Chloride channel protein 2
Exprimiert in: Human cells
Ursprungsart: human
1.336,00 €
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Human CLCN2 full length protein-synthetic nanodisc
Human CLCN2 full length protein-synthetic nanodisc

Artikelnummer: DIM-FLP100619.10

This gene encodes a voltage-gated chloride channel. The encoded protein is a transmembrane protein that maintains chloride ion homeostasis in various cells. Defects in this gene may be a cause of certain epilepsies. Four transcript variants encoding different isoforms have been found for this gene. [provided by...
Schlagworte: CLCN2, ClC-2, Chloride channel protein 2
Anwendung: Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization
Exprimiert in: Human cells
Ursprungsart: human
MW: 98.5 kD
ab 1.291,00 €
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