Zu "K05001" wurden 19 Artikel gefunden!
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Repaglinide
Artikelnummer: Cay19387-100
Repaglinide is a metaglitinide antidiabetic agent that blocks ATP-dependent potassium (Kir6) channels in pancreatic beta-cells (Kd = 0.42 nM for the sulphonylurea receptor SUR1 when co-expressed with Kir6.2). In vivo, repaglinide lowers blood glucose in fasted rats and dogs (ED50s = 10 and 28.3 µg/kg, respectively)....
| Schlagworte: | 2-ethoxy-4-[2-[[(1S)-3-methyl-1-[2-(1-piperidinyl)phenyl]butyl]amino]-2-oxoethyl]-benzoic acid |
| Anwendung: | Kir6 blocker |
| CAS | 135062-02-1 |
| MW: | 452.6 D |
ab 146,00 €
Repaglinide-d5
Artikelnummer: Cay26104-1
Repaglinide-d5 is intended for use as an internal standard for the quantification of repaglinide (Cay-19387) by GC- or LC-MS. Repaglinide is a metaglitinide antidiabetic agent that blocks ATP-dependent potassium (Kir6) channels in pancreatic beta-cells (Kd = 0.42 nM for the sulphonylurea receptor SUR1 when...
| Schlagworte: | 2-(ethoxy-1,1,2,2,2-d5)-4-[2-[[(1S)-3-methyl-1-[2-(1-piperidinyl)phenyl]butyl]amino]-2-oxoethyl]-benzoic acid |
| Anwendung: | GC-MS, LC-MS, internal standard, Kir6 blocker |
| CAS | 1217709-85-7 |
| MW: | 457.6 D |
ab 228,00 €
Anti-KCNJ8 / kir6.1, clone S366-60
Artikelnummer: ARG23904.50
Protein function: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external...
| Schlagworte: | Anti-Kcnj8, Anti-uKATP-1, Anti-Inward rectifier K(+) channel Kir6.1, Anti-ATP-sensitive inward rectifier potassium channel... |
| Anwendung: | ICC, IF, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, rat |
584,00 €
Anti-KCNJ8
Artikelnummer: ATA-HPA031066.100
Protein function: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external...
| Schlagworte: | Anti-KCNJ8, Anti-uKATP-1, Anti-Inward rectifier K(+) channel Kir6.1, Anti-ATP-sensitive inward rectifier potassium channel... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 246,00 €
Repaglinide D5
Artikelnummer: TGM-T19548-1mg
Description: Repaglinide D5 is deuterium labeled Repaglinide. Repaglinide is an insulin secretagogue for treatment type-2 diabetes mellitus. Smiles: [2H]C([2H])([2H])C([2H])([2H])Oc1cc(CC(=O)N[C@@H](CC(C)C)c2ccccc2N2CCCCC2)ccc1C(O)=O. References: Wang LC, et al. Characteristics of repaglinide and its mechanism of...
| Schlagworte: | AG-EE 623ZW D5 |
| Anwendung: | GC-MS, LC-MS, internal standard, Kir6 blocker |
| CAS | 1217709-85-7 |
| MW: | 457.62 D |
300,00 €
KCNJ8 (human), recombinant protein
Artikelnummer: ABS-PP-25748-L.100
Protein function: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external...
| Schlagworte: | KCNJ8, uKATP-1, Inward rectifier K(+) channel Kir6.1, ATP-sensitive inward rectifier potassium channel 8, Potassium... |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 12.5 kD |
ab 115,00 €
KCNJ8 (human), recombinant protein
Artikelnummer: ABS-PP-25748.100
Protein function: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external...
| Schlagworte: | KCNJ8, uKATP-1, Inward rectifier K(+) channel Kir6.1, ATP-sensitive inward rectifier potassium channel 8, Potassium... |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 12.5 kD |
ab 90,00 €
Kcnj8, Rat potassium inwardly-rectifying channel,...
Artikelnummer: VRPS-3115
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
| Schlagworte: | Kcnj8, uKATP-1, Inward rectifier K(+) channel Kir6.1, ATP-sensitive inward rectifier potassium channel 8, Potassium... |
| Anwendung: | RNA quantification |
54,00 €
KCNJ8, Human potassium inwardly-rectifying channel,...
Artikelnummer: VHPS-4766
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
| Schlagworte: | KCNJ8, uKATP-1, Inward rectifier K(+) channel Kir6.1, ATP-sensitive inward rectifier potassium channel 8, Potassium... |
| Anwendung: | RNA quantification |
45,00 €
Kcnj8, Mouse potassium inwardly-rectifying channel,...
Artikelnummer: VMPS-3269
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
| Schlagworte: | Kcnj8, uKATP-1, Inward rectifier K(+) channel Kir6.1, ATP-sensitive inward rectifier potassium channel 8, Potassium... |
| Anwendung: | RNA quantification |
45,00 €
Anti-KCNJ8, NT (KCNJ8, ATP-sensitive inward rectifier...
Artikelnummer: 037331.200
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a...
| Schlagworte: | Anti-KCNJ8, Anti-uKATP-1, Anti-Inward rectifier K(+) channel Kir6.1, Anti-ATP-sensitive inward rectifier potassium channel... |
| Anwendung: | ELISA, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
865,00 €
Anti-KCNJ8
Artikelnummer: NSJ-RQ6193
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Potassium inwardly-rectifying channel, subfamily J, member 8, also known as KCNJ8, is a human gene encoding the Kir6.1 protein. Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein...
| Schlagworte: | Anti-KCNJ8, Anti-uKATP-1, Anti-Inward rectifier K(+) channel Kir6.1, Anti-ATP-sensitive inward rectifier potassium channel... |
| Anwendung: | WB, IHC (paraffin), FC, Direct ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €